How to take cycloferon tablets. Cycloferon: instructions for use

Cycloferon is a popular antiviral medicine domestic production which increases the body's resistance. It is a high-molecular activator of the formation of interferon and has the widest spectrum of pharmacological activity.

high therapeutic activity drug is due to the spectrum biological action. Effective in the treatment of diseases viral nature, including influenza, it is also practiced to prescribe cycloferon for some bacterial infections, as an immunostimulant. Traditionally used for immunodeficiencies of varying severity, including HIV infection. It is characterized by an anticarcinogenic effect and suppresses the development of autoimmune reactions, which further expands therapeutic spectrum drug.

Cycloferon has been present on the pharmaceutical market for more than 20 years, has an affordable price in its segment and is the drug of choice for immunodeficiencies, as well as for diseases of a viral nature.

Composition, physical and chemical properties, price

The drug is produced in 3 dosage forms: liniment for local external use, oral tablets and parenteral solution.

pharmachologic effect

Cycloferon has 2 pronounced effects: antiviral and immunomodulatory, as well as anti-inflammatory, antiproliferative (suppresses excessive cell growth) and antitumor effects. In the body, meglumine acridone acetate potentiates the synthesis and accumulation in organs and tissues of significant titers of interferons α and β. Wherein greatest content interferons are observed in structures rich in lymphoid tissue: spleen, lungs, intestinal mucosa, liver.

Cycloferon activates bone marrow stem cells, ensures the formation of granulocytes. Normalizes the ratio of T-suppressors, which suppress the formation of antigens, and T-helpers, which enhance the adaptive immune response. Activates killer cells and T-lymphocytes. This effect is especially important in immunodeficiencies. different nature, because it leads to the correction of the immune status. Penetrates into brain tissue.

Thus, cycloferon:

1. leads to marked improvement in common viral diseases like flu, herpes, enterovirus infection, and with less common pathologies: tick-borne encephalitis, hepatitis, cytomegalovirus and papillomatous infections;
2. normalizes the immune status in HIV-infected people;
3. has an antimicrobial and antichlamydial effect;
4. warning start tumor processes due to antimetastatic and anticarcinogenic effects;
5. suppresses autoimmune reactions, thereby reducing the severity of pain and inflammation in rheumatic diseases and systemic pathologies connective tissue;
6. causes an improvement in the balance of immunity, with topical application characterized by antiproliferative action and rapid elimination inflammation.

Pharmacokinetics

After oral intake after 2-3 hours reaches the maximum plasma concentration. Gradually, the concentration of the drug decreases and after a day, cycloferon is found in the body in a residual amount.

The half-life is 4-5 hours. In therapeutic dosages, no accumulation of meglumine acridone acetate is observed.

Indications

Tablets are prescribed in complex therapy in adults with:

• flu and acute respiratory infections;
• herpes;
• AII of viral etiology;
• neuroinfections, including tick-borne borreliosis and encephalitis, serous meningitis;
• secondary immunodeficiency against the background chronic infections caused by fungi and bacteria;
• hepatitis C and B (chronic);
• HIV infection in stage 2A-3B;

In children, cycloferon tablets are used as part of complex therapy for:

• infections of herpetic etiology;
• hepatitis C and B (both acute and chronic);
• HIV infection in stage 2A-3B;
• viral intestinal infections;
• ARI and influenza, as well as for their prevention.

The solution, as a drug of complex therapy, is indicated for the treatment of adult patients with the following conditions:

• HIV infection in stage 2A-3B;
• hepatitis C, D, A, B;
• systemic connective tissue diseases and rheumatic diseases ( rheumatoid arthritis, SLE);
• neuroinfections, incl. with tick-borne borreliosis and encephalitis, serous meningitis;
• infections caused by cytomegalovirus and herpes virus;
• secondary immunodeficiency due to fungal and bacterial infections, acute and chronic;
• chlamydial infections;
• joint pathologies (degenerative-dystrophic), incl. with deforming osteoarthritis.

In children from 4 years parenteral administration cycloferon is indicated for:

• viral hepatitis C, A, D, GP and B;
• HIV infection (stage 2A-3B);
• herpetic infection.

Liniment cycloferon is a component of complex therapy and is applied topically in adults with:

• herpetic infection;
• nonspecific vaginosis and bacterial vagititis;
• specific urethritis (gonorrheal, candidal, chlamydial, trichomonas), balanoposthitis, as well as nonspecific urethritis.

Contraindications

1. Decompensated cirrhosis of the liver - for tablets and solution;
2. Hypersensitivity to the components of all dosage forms;
3. Children's age up to 4 years (solution and tablets) and up to 18 years (liniment);

Many are interested in whether cycloferon is possible during pregnancy and lactation. The answer is unequivocal - all forms of the drug are contraindicated.

special instructions

It is used with caution for erosions, gastritis, stomach / duodenal ulcers, duodenitis in the acute stage, as well as for severe allergic reactions.

Treatment with a solution and tablets for thyroid dysfunction should be carried out with the participation and control of an endocrinologist.

Does not slow down the reaction rate.

Instructions for use of cycloferon

Tablets, for adults

The drug is taken once a day, half an hour before meals, without crushing and drinking water. The dose depends on the disease and age.

• herpetic infection. At a dose of 2-4 tablets. according to the scheme: on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20th and 23rd days - this is the basic scheme suitable for most pathologies. On the course treatment- 20-40 tab. Start treatment with an exacerbation of the disease;
• ARI and influenza. Adults 2-4 tablets. once / day, 10-20 tab. on the course from the first symptoms. At severe flu a single dose increases to 6 tablets. Prescribe other drugs for symptomatic treatment(antipyretic, etc.);
• Chronic hepatitis C and B. According to 4 tables. according to the basic scheme, then - 4 tab. once in 3-5 days about 3.5 months. The course requires 100-150 tablets. In the treatment of hepatitis C or mixed infection, repeated courses are prescribed, in combination with other antiviral and interferon;
• Intestinal infections (as a component complex treatment): 2 tab. for admission according to the basic scheme until the 8th day, and from the 11th - 4 tablets each;
• Neuroinfections. In a dose of 4 tablets. according to the basic scheme, then - 4 tab. in 5 days. The course of treatment is 2.5 months;
• HIV infection. In a dose of 4 tablets. according to the basic scheme, then at the same dose 1 time in 3-5 days for 2.5 months. After 2-3 weeks, the course is repeated (the course takes 100-150 tablets);
• Immunodeficiencies. 2 tab. according to the basic scheme.

How to take cycloferon in childhood

The drug is taken once a day, half an hour before meals, washed down with water.

• Children 4-6 years old: 1 tablet per appointment;
• Children 7-11 years old: 2 tablets per appointment;
• Children from 12 years old: at the reception, 3 tablets.

The treatment regimen depends on the pathology:

• Acute viral hepatitis C, B: the recommended dose by age is twice in 1 day, then they switch to a three-time dose after 48 hours, and then - 5 doses every 72 hours;
• Chronic viral hepatitis C and B: in the recommended doses by age after 48 hours, per course 50-150 tablets;
• HIV infection: age dose for 1, 2, 4, 6, 8, 11, 14, 17, 20 days, then according to the maintenance regimen once every 3-5 days for about 5 months;
• Herpetic infection: 1, 2, 4, 6, 8, 11, 14 days - at the age dose, then - based on the severity of the pathology;
• Intestinal infections: once a day. in an age dose for 1, 2, 4, 6, 8, 11 days (6-18 tablets per course);
• Influenza and acute respiratory infections: in age doses with a daily interval, 5-9 doses of cycloferon per course of treatment;
• During an unfavorable situation for influenza and other acute respiratory viral infections for their prevention: the age dose, which is taken on the 1st, 2nd, 4th, 6th, 8th day, then 5 more times after 72 hours. Preventive course: 10-30 tablets.

Scheme for the use of cycloferon injections in adults

The solution is administered intravenously or intramuscularly once a day. according to the basic scheme: for 1, 2, 4, 6, 8, 11, 14, 17, 20, 23, 26, 29 days. The dose depends on the pathology.

• Viral hepatitis B, A, D, C. Single dose - 250-500 mg, total total dose of 2.5-5 g per course. In total, 10 injections are prescribed, after 2 weeks. the course is repeated;
• Infections associated with herpes and cytomegalovirus: 10 injections of 250 mg each (total dose per course 2.5 g). It works most effectively when treated at the very beginning of an exacerbation;
• Neuroinfections. 12 injections at a dose of 250-500 mg. Treatment is combined with etiotropic therapy. General dose: 3-6 g. Re-treatment is allowed;
• HIV infection. single dose- 500 mg, 10 injections are administered intramuscularly according to the basic scheme. Supportive treatment prescribed after the course: 500 mg once every 5 days for 2.5 months. 30 days after the end - a repeated therapeutic course;
• Chlamydial infections. 250 mg, 10 injections per course. Re-treatment is carried out after 2 weeks. after the end of the course. In this case, it is recommended to use cycloferon together with antibiotics;
• immunodeficiency states. 250 mg intramuscularly, 10 injections. After 6-12 months. a second course is recommended;
• Systemic pathologies of connective tissue and rheumatic diseases. 5 injections for 4 courses (in 10-14 days), in a single dose of 250 mg. Repeated courses are prescribed by a doctor;
• Diseases musculoskeletal system degenerative-dystrophic character. 250 mg - 2 courses of 5 injections, with an interval of 10-14 days;

Scheme for the use of cycloferon injections in children

The dose of cycloferon solution is calculated individually: 6-10 mg/kg of the child's body weight. Enter intramuscularly or intravenously, once a day.

• Acute hepatitis B, C, A, GP, D and mixed forms: dose based on body weight, which is administered at 1, 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28 days. With a protracted infection after 14 days, repeat according to the same scheme;
• Chronic hepatitis C, B, GP, D. Dose according to body weight, which is administered on days 1, 2, 4, 6, 8, 10, 12, 14, 16, 18, then a maintenance regimen is prescribed for 3 months, 1 injections after 3 days;
• HIV infection. Enter according to the scheme of chronic hepatitis therapy, then: maintenance scheme once every 5 days for 3 months;
• herpetic infection. The weight-based dose is administered on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20th, 23rd day, after which to maintain the effect: 1 injection every 5 days.

Cycloferon scheme - topical application

• herpetic infection. Liniment is applied to the affected area thin layer once a day for 5 days. With genital herpes, daily intraurethral or intravaginal instillations of 5 ml of liniment (1 bottle) are made 1 time per day. 10-15 days. Liniment can be combined with other general and local antiherpetic drugs;
• Candidal, nonspecific urethritis. Make instillations of 5-10 ml of liniment (volume 1-2 vials) into the urethra. The dose varies according to the severity of the lesion.
  • with the development of inflammation in anterior section urethra in men, the cannula of the syringe with liniment is immersed in the outer opening of the canal, then the opening is gently squeezed for 1.5-3 minutes. After some time, the instillation solution is released by gravity. You need to urinate in half an hour (otherwise swelling of the mucous membrane may develop).
  • in case of damage to the seminal glands or the posterior urethra, intraurethral instillations of the liniment are performed using urethral catheter 5-10 ml for 10-14 days in a row, once a day.
  • in the treatment of specific urethritis, the use of antibacterial agents to which the pathogenic flora is sensitive.
• Candidiasis and nonspecific colpitis, bacterial vaginosis, endocervicitis. Assign instillations of liniment into the vagina, 5-10 ml daily, 10-15 days. In order for the liniment not to leak out, the vaginal entrance should be plugged with a small sterile swab for 2-3 hours.
• When diagnosing a combined intraurethral and intravaginal infection, instillations should be used both in the vagina and in the urethra, 5 ml each for 10-15 days. The introduction of impregnated sterile swabs is allowed.

Liniment is combined with vaginal forms drugs (suppositories, tablets), so it can be used in combination with chronic pathology female genital area.

The treatment regimens suggested above are basic and may vary on an individual basis.

Side effects

Perhaps the manifestation of general and local reactions hypersensitivity.

drug interaction

The drug is 100% compatible with other drugs that are traditionally used in the treatment of these diseases, including interferons, chemotherapeutic and symptomatic remedies. An increase in the effects of nucleoside analogues and interferons was noted with joint application with cycloferon.

One of positive effects cycloferon is a decrease in the severity side effects interferon therapy and chemotherapy.

Analogues

Analogues in composition this moment not registered.

The flu is pathological process, the essence of which is the defeat of the body by an acute viral infection. Every year in the autumn-winter period, influenza is actively spreading, resulting in an epidemic. Treatment should be started as soon as the first symptoms are detected.

And although there are many anti-flu drugs today, doctors and patients actively use Cycloferon. Due to its wide spectrum of influence, the drug can be taken both for treatment and for prevention.

Action for colds

Cycloferon is an immunomodulatory drug that belongs to low molecular weight interferon inducers. It is this component that determines the spectrum of influence of Cycloferon on the human body.

With a cold, the drug has the following effect:

After the components of Cycloferon have penetrated the body, they immediately begin to show their influence, suppressing the function that is responsible for the reproduction process. Thanks to its constituent interferon, it is possible to activate the production of antibodies in different bodies and tissues, improve the functioning of stem cells bone marrow and positively affect the formation of white cells in the lymph. It is the white cells that create reliable protection from the penetration of infections.

Oral administration of Cycloferon maximum effect can be obtained in 2-3 hours, and after its concentration is declining.

But there are cases when, after a day, residual components are still found in the blood. When using the drug in the form of injections, the peak effect of the drug occurs 1-2 hours after its administration.

Cycloferon liniment- This is an interferon inducer, presented in the format of a liquid ointment. It is used in the treatment of various infectious pathologies, including those that are sexually transmitted. Ointment Cycloferon has a number of contraindications. You can not use it during pregnancy and lactation, children, as well as people who have hypersensitivity to the active components of the ointment.

On the video, how to take cycloferon in tablets for a cold:

Release form

cycloferon is produced in the form of tablets, ointments and injections. The tablets are biconvex and have yellow shell. And the solution can be used for intravenous or intramuscular injection.

Considering the solution, 1 ml contains 125 mo of meglumine acridone acetate and water. The drug is sold in ampoules of 2 ml, in one carton there are 5 of them.

The composition of one tablet contains 150 ml of meglumine acridone acetate and such additional auxiliary components: polysorbate 80, povidane, propylene glycol, calcium stearate, methacrylic acid copolymer. Sale of tablets in blisters. In one, the number of tablets is 10 pieces.

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And Cycloferon can be seen in the form of an ointment. This medication has a pronounced anti-inflammatory, immunomodulatory and antiviral effect. The composition of the ointment contains muglumine acridone acetate and methylglucamine, as well as a number of additional components.

How to take pills

It is necessary to take Cycloferon for colds and flu according to a certain scheme. It is important to take the drug on the first day of the disease, upon detection of the first symptoms. These include a rise in body temperature, headache, weakness, sore throat, aches.

Take the tablet 30 minutes before meals. If flu and colds are being treated, then the intake is once a day, preferably in the morning.

On the video, how to drink cycloferon with a cold for adults:

For getting positive result You need to follow a few simple guidelines:

1. The first time to drink the drug on the first day of the disease. The number of tablets will be 4 pieces. If observed heat and a severe course of a viral infection, then 6 tablets can be consumed. All of this can be taken in one go.
2. In the next 3 days, take 2-4 tablets.
3. If you want to long-term use, the decision is made by the doctor if necessary.
4. For children, the dosage of the drug is different from the adult. If the patient is not yet 6 years old, then he needs to take 1 tablet per day, but from 6 to 11 years old - 2 tablets, from 11 to 16 years old - 3 tablets.

Together with Cycloferon, you can take antipyretics, antihistamines. In addition, it is important to drink plenty of fluids. Daily rate will be 2 liters. And it's not just water. With a cold, you can drink compotes, teas and fruit drinks.

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There are contraindications. Consult your doctor.

Currently, analogues of the drug are NOT FOR SALE

Preparations containing Meglumine acridonacetate (ATC code not assigned):

Cycloferon - instructions for use. Prescription drug, information intended for healthcare professionals only!

Clinico-pharmacological group:

Antiviral and immunomodulatory drug. Interferon synthesis inducer

pharmachologic effect

Immunomodulator. Meglumine acridonacetate is a low molecular weight interferon inducer, which determines wide range its biological activity (antiviral, immunomodulatory, anti-inflammatory). Interferonogenic activity of the drug at oral administration kept for 3 days.

The main cells-producers of interferon after the administration of the drug are macrophages, T- and B-lymphocytes. The drug induces high titers of interferon in organs and tissues containing lymphoid elements (spleen, liver, lungs), activates bone marrow stem cells, stimulating the formation of granulocytes. Cycloferon® activates T-lymphocytes and natural killer cells, normalizes the balance between subpopulations of T-helpers and T-suppressors. Enhances the activity? -interferons.

Possesses direct antiviral action by inhibiting the reproduction of the virus early dates(1-5 days) infectious process, reducing the infectivity of viral progeny, leading to the formation of defective viral particles. Increases the body's nonspecific resistance against viral and bacterial infections.

Cycloferon® is effective against viruses tick-borne encephalitis, influenza, hepatitis, herpes, cytomegalovirus, human immunodeficiency virus, papillomavirus and other viruses. For acute viral hepatitis Cycloferon® prevents the transition of diseases into a chronic form. At the stage of primary manifestations of HIV infection, it contributes to the stabilization of immunity indicators.

The high efficiency of the drug in the complex therapy of acute and chronic bacterial infections (neuroinfections, chlamydia, bronchitis, pneumonia, postoperative complications, urogenital infections, peptic ulcer) as a component of immunotherapy. Meglumine acridonacetate is highly effective in rheumatic and systemic diseases connective tissue, suppressing autoimmune reactions and providing anti-inflammatory and analgesic effects.

Pharmacokinetics

Tablets

After taking the drug orally at the maximum allowable dose Cmax in blood plasma is reached after 2-3 hours, the concentration gradually decreases by 8 hours, after 24 hours active substance found in trace amounts.

T1 / 2 is 4-5 hours. When using Cycloferon in recommended doses, there are no conditions for its accumulation in the body.

Injection

When administered at the maximum allowable dose, Cmax in blood plasma is reached after 1-2 hours. After 24 hours, the active substance is detected in trace amounts.

Penetrates through the BBB.

T1 / 2 is 4-5 hours. long-term use cumulation in the body is not observed.

Indications for the use of the drug CYKLOFERON®:

For oral administration:

• herpetic infection;
• influenza and acute respiratory infections;
• acute intestinal infections;
• neuroinfections, including serous meningitis, tick-borne borreliosis (Lyme disease);
• HIV infection (stages 2A-2B);
• secondary immunodeficiencies associated with chronic bacterial and fungal infections.

As part of complex therapy in children older than 4 years:

• herpetic infection;
• prevention and treatment of influenza and acute respiratory diseases;
• chronic viral hepatitis B and C;
• acute intestinal infections;
• HIV infection (stage 2A-2B).

For parenteral use:

As part of complex therapy in adults:

• HIV infection (stages 2A-2B);
• neuroinfections: serous meningitis and encephalitis, tick-borne borreliosis (Lyme disease);
• viral hepatitis A, B, C, D;
• herpetic infection;
• cytomegalovirus infection;
• secondary immunodeficiencies associated with acute and chronic bacterial and fungal infections;
• chlamydial infections;
• rheumatic and systemic connective tissue diseases (rheumatoid arthritis, systemic lupus erythematosus);
• degenerative-dystrophic diseases of the joints (including deforming osteoarthritis).

As part of complex therapy in children:

• viral hepatitis A, B, C, D;
• herpetic infection;
• HIV infection (stages 2A-2B).

For outdoor use:

As part of complex therapy in adults:

• herpetic infection of the skin and mucous membranes;
• treatment of urethritis and balanoposthitis of nonspecific and specific (gonorrheal, candidal, chlamydial and trichomonas) etiology;
• treatment of non-specific bacterial vaginitis and vaginosis;
• treatment of chronic periodontitis.

Dosing regimen:

Inside:

Cycloferon® in the form of tablets is taken 1 time per day 30 minutes before meals, without chewing.

For adults with herpetic infection, the drug is prescribed 4 tablets per dose on days 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23. The course of treatment - 40 tablets. Treatment is most effective when the first symptoms of the disease appear.

In the treatment of influenza and acute respiratory diseases, 4 tablets are prescribed per reception for 1, 2, 4, 6, 8 days. The course of treatment - 20 tablets. Treatment should be started at the first symptoms of infection. In severe cases of the disease, 6 tablets are taken at the first dose. If necessary, additional symptomatic therapy(antipyretic, analgesic, expectorant).

In chronic viral hepatitis B and C, the drug is taken 4 tablets per dose on days 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 of treatment and then according to the maintenance regimen, 4 tablets per dose 1 time in 3 days for 6 months while maintaining replicative and cytolytic activity up to 12 months. A combination with interferons and antiviral drugs is recommended.

In the complex therapy of intestinal infections, 2 tablets per dose are used on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th, 17th, 20th and 23rd days. The course of treatment - 20 tablets.

For neuroinfections, 4 tablets per dose are prescribed for 1, 2, 4, 6, 8, 11, 14, 17, 20 and 23 days and then, according to the maintenance regimen, 4 tablets per dose 1 time in 3 days for 2.5 months. The course of treatment - 140 tablets.

In case of HIV infection (stages 2A-2B), the drug is prescribed for 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days, 4 tablets per dose, and then maintenance treatment is carried out, 4 tablets 1 time in 3 days for 2.5 months. The course of treatment - 140 tablets. A second course is carried out after 2-3 weeks. after the end of the previous 2-3 times.

At immunodeficiency states associated with chronic bacterial and fungal infections, 4 tablets are prescribed in the first 5 doses on days 1, 2, 4, 6, 8 and 2 tablets in the next 5 doses on days 11, 14, 17, 20, 23. The course of treatment - 30 tablets.

Cycloferon® children are prescribed according to the following basic scheme: at the age of 4-6 years - 150 mg (1 tablet), at the age of 7-11 years - 300 mg (2 tablets), over 12 years old - 450 mg (3 tablets) per reception 1 time per day. It is advisable to repeat the course 2-3 weeks after the end of the first course.

With herpes infection, they are taken on the 1st, 2nd, 4th, 6th, 8th, 11th, 14th days of treatment. The course of treatment may vary depending on the severity of the condition and the severity clinical symptoms.

For influenza and acute respiratory viral infections, the drug is prescribed in age doses for 1, 2, 4, 6, 8, 11, 14, 17, 20, 23 days and then 1 time in 3 days. The course of treatment is from 5 to 15 doses, depending on the severity of the condition and the severity of the symptoms.

As a means of emergency non-specific prevention of acute respiratory diseases and influenza during the period of increased incidence, the drug is prescribed in the indicated age doses for 1, 2, 4, 6, 8 days, then 5 more times with an interval of 72 hours (3 days).

At chronic forms hepatitis B and / or C, the drug is prescribed in the indicated doses on days 1, 2, 4, 6, 8, 11, 14 and then 1 time in 3 days for 6 months while maintaining replicative and cytolytic activity up to 12 months. A combination with interferons and antiviral drugs is recommended.

In acute intestinal infections, the drug is prescribed for 1, 2, 4, 6, 8, 11 days of treatment 1 time per day. The course of treatment - 6-18 tablets.

With HIV infection (stages 2A-2B), the drug is taken according to the basic scheme for 1, 2, 4, 6, 8, 11, 14, 17, 20 days of therapy, then 1 time in 3 days for 5 months.

Parenteral application:

For adults, Cycloferon® is administered intramuscularly or intravenously 1 time per day according to the basic scheme: every other day. The duration of treatment depends on the disease.

For herpetic and cytomegalovirus infections the drug is prescribed according to the basic scheme - 10 injections of 250 mg. The total dose is 2.5 g. Treatment is most effective at the beginning of an exacerbation of the disease.

In case of neuroinfections, the drug is administered according to the basic scheme. The course of treatment - 12 injections of 250-500 mg in combination with etiotropic therapy. The total dose is 3-6 g. Repeated courses are carried out as needed.

With chlamydial infection, treatment is carried out according to the basic scheme. The course of treatment is 10 injections of 250 mg. The total dose is 2.5 g. The second course is in 10-14 days. It is advisable to combine Cycloferon with antibiotics.

In acute viral hepatitis A, B, C, D and mixed forms the drug is administered according to the basic scheme of 10 injections of 500 mg. The total dose is 5 g. In case of a protracted course, a second course is carried out after 10-14 days.

In chronic viral hepatitis B, C, D and mixed forms, the drug is administered according to the basic scheme of 10 injections of 500 mg, then according to the maintenance scheme 3 times a week. within 3 months as part of complex therapy. Recommended in combination with interferons and chemotherapy. The course is repeated in 10-14 days.

With HIV infection (stage 2A-2B), the drug is prescribed according to the basic scheme of 10 injections of 500 mg each, and then according to the maintenance regimen once every three days for 2.5 months. The course is repeated after 10 days.

In immunodeficiency states, the course of treatment consists of 10 intramuscular injections according to the basic scheme in a single dose of 250 mg. The total dose is 2.5 g. The second course is carried out after 6-12 months.

In case of rheumatic and systemic diseases of the connective tissue, 4 courses of 5 injections are prescribed according to the basic scheme, 250 mg each with a break of 10-14 days. The doctor determines the need for a second course individually.

In degenerative-dystrophic diseases of the joints, 2 courses of 5 injections of 250 mg each are prescribed with a break of 10-14 days according to the basic scheme. The doctor determines the need for a second course individually.

For children, Cycloferon® is prescribed intramuscularly or intravenously 1 time per day. The daily therapeutic dose is 6-10 mg/kg of body weight.

In acute viral hepatitis A, B, C, D and mixed forms, 15 injections of the drug are carried out according to the basic scheme. With a protracted course of infection, the course is repeated after 10-14 days.

In chronic viral hepatitis B, C, D, the drug is administered according to the basic scheme of 10 injections and then according to the maintenance regimen 3 times a week for 3 months as part of complex therapy. Use in combination with interferons and chemotherapy is recommended.

In case of HIV infection (stages 2A-2B), a course of 10 injections is prescribed according to the basic scheme and then according to the maintenance regimen 1 time in 3 days for 3 months. A second course is carried out after 10 days.

With a herpes infection, a course of 10 injections is carried out according to the basic scheme. While maintaining the replicative activity of the virus, the course of treatment is continued according to the maintenance scheme with the introduction of the drug 1 time in 3 days for 4 weeks.

Outdoor use:

In case of herpetic infection, the liniment is applied in a thin layer to the affected area 1-2 for 5 days. With genital herpes - intraurethral (intravaginal) instillations 1 time per day, 5 ml for 10-15 days daily. It is possible to combine liniment with other antiherpetic drugs (both systemic and local).

In the treatment of nonspecific and candidal urethritis, intraurethral instillations are performed in a volume of 5-10 ml, depending on the level of the lesion. urethra. When defeated upper division urethra in men, the cannula of a syringe with liniment is inserted into the external opening of the urethra, then the opening is clamped for 1.5-3 minutes, after which the instillation solution is evacuated by gravity. After 30 minutes, the patient is advised to urinate. Longer exposure may lead to swelling of the urethral mucosa. The course of treatment is 10-14 days. With lesions of the posterior urethra, the area of ​​the seminal glands, intraurethral instillations are used through a catheter in a volume of 5-10 ml of the drug for 10-14 days every other day (for a course of 5-7 instillations).

In the treatment of urethritis of a specific etiology, the combined use of intraurethral instillations of Cycloferon with specific antimicrobial drugs according to traditional schemes.

With balanoposthitis, the glans penis should be treated and foreskin liniment Cycloferon 1 time per day (1/2 bottle or 5 ml) for 10-14 days.

In the treatment of candidal vaginitis, nonspecific vaginitis (endocervicitis) and bacterial vaginosis it is possible to use the drug both in the form of monotherapy and in the course of complex treatment. Apply intravaginal instillations of the drug, 5-10 ml, for 10-15 days, 1-2 times a day. In parallel, in the case of a combined lesion of the vaginal mucosa and urethra, it is advisable to use intravaginal and intraurethral instillations in volume (5 ml daily for 10-14 days). It is possible to use tampons impregnated with liniment.

In chronic forms of diseases, the drug is well combined with the use of official medicines ( vaginal tablets, candles).

For intravaginal use, open the tube, pierce the membrane with a disposable needle with a syringe (volume 5 ml), collect liniment, remove and discard the needle. Enter the filled syringe in the supine position into the vagina and squeeze out the liniment with the help of a piston. If there is a vaginal applicator in the package: pierce the membrane, screw the applicator until it stops on the hole. Squeeze the liniment into the applicator cavity until the entire piston is pushed out. Remove the filled applicator from the hole, insert into the vagina and squeeze out the liniment with the help of a piston. To prevent free evacuation of the drug, the entrance to the vagina is tamponed with a small sterile cotton swab for 2-3 hours.

During treatment chronic periodontitis before applying the liniment, it is desirable to wash the periodontal pockets with an antiseptic, then apply the liniment with a cotton swab in a volume of 1.5 ml (1/3) on the gum by application (do not rub) 1-2 with an interval of 10-12 hours. The duration of therapy is 12-14 days.

For all indications, if necessary, you can repeat the course of treatment with Cycloferon after 14 days.

Side effect

Possibly: allergic reactions.

Contraindications to the use of the drug CYKLOFERON®

• cirrhosis of the liver in the stage of decompensation;
• childhood up to 4 years;
• pregnancy;
• lactation period ( breastfeeding);
• hypersensitivity to the components of the drug.

The use of the drug CYKLOFERON® during pregnancy and lactation

The drug is contraindicated for use during pregnancy and lactation (breastfeeding).

Application for violations of liver function

Contraindicated in cirrhosis of the liver in the stage of decompensation.

special instructions

For diseases thyroid gland the use of Cycloferon should be carried out under the supervision of an endocrinologist.

In the treatment of influenza and SARS, in addition to therapy with Cycloferon, symptomatic therapy should be carried out.

Influence on the ability to drive vehicles and control mechanisms

Cycloferon® does not affect the ability to drive vehicles.

Overdose

To date, no cases of drug overdose have been reported.

drug interaction

Cycloferon® is compatible with all drugs used in the treatment of these diseases (including interferons and chemotherapy drugs).

Cycloferon® enhances the action of interferons and nucleoside analogues.

When used together, Cycloferon® reduces side effects chemotherapy and interferon therapy.

Terms of dispensing from pharmacies

The drug is dispensed by prescription.

Terms and conditions of storage

List B. Enteric-coated tablets should be stored in a dry, dark place at a temperature of 10° to 25°C. Shelf life - 2 years.

Solution for injection should be stored in a dry, dark place at a temperature of 0° to 25°C. Freezing solution for injection during transportation (with negative temperature) does not change properties. Thawed at room temperature, the drug retains its biological and physiochemical properties. If the color of the solution changes and a precipitate forms, the use of the drug is unacceptable. Shelf life - 3 years.

Colds are most often encountered by babies due to reduced immunity. What medicine to use to get the child on his feet as quickly as possible? Many wonderful statements can be heard about the drug "Cycloferon". Instructions for use for children should be studied first. It is also important to consult with your pediatrician. Self-medication is not advisable.

Description of the medicinal product

"Cycloferon" belongs to the category of anti-inflammatory, immunostimulating antiviral agents. The drug is produced in various forms. This is an ointment, injection solution, tablets. The medicine is widely used for prophylaxis during the period of seasonal cold weather. With its help, it is possible to prevent influenza and acute respiratory infections in a child in winter time. As active component any dosage form uses acridonacetic acid. The composition of the tablets additionally includes methylcellulose, calcium stearate. The composition of the solution also uses water for injection, and a salt-forming additive.

The liniment (ointment) "Cycloferon" is also widely used. Children from one year old medication can be used. Propylene glycol, catapol (antiseptic) are used as inactive components.

For the treatment of patients younger age widely used candles "Cycloferon". For a child with ARVI, the drug helps to restore normal health as quickly as possible. Interferon synthesis inductor, acridoneacetic acid, allows you to speed up the healing process. The drug stimulates defensive forces organism, due to which the child already on the next day after the start of therapy behaves more actively, disappear unpleasant symptoms illness.

What else is famous for the drug "Cycloferon"? Instructions for use for children show that the drug is effective against the herpes virus. In addition, the drug can be used as part of the complex therapy of bacterial infections. But treatment in any case should be prescribed by a qualified specialist.

Indications

When can the drug "Cycloferon" be prescribed to children from a year old? The drug is primarily used for complex forms SARS or influenza when present big risk the development of complications. The medication is strong enough. Therefore, if the child's body can overcome the infection on its own, you should not interfere with it. The drug primarily stimulates the immune system. Widely used "Cycloferon" for the prevention of children. How to take medicine in this case? The doctor will tell you the exact dosage.

The drug is often prescribed as part of the complex therapy of various intestinal infections. The medication can be used with various states organisms associated with immune deficiency. This chronic hepatitis, HIV, Lyme disease, chlamydial infections, joint diseases, etc.

For prevention, a remedy can be prescribed to a child if he often suffers from viral colds or herpes infections.

It is worth remembering that the drug "Cycloferon" is not vitamins. In no case should you take a remedy in order to protect your child from colds in winter. Therapy should be prescribed by a specialist. Prevention is carried out only for weakened, often ill younger patients.

Contraindications

It is no coincidence that you should consult a doctor before starting treatment with Cycloferon. Instructions for use for children describe a number dangerous contraindications. non-compliance simple rules may lead to the development of side effects. Under no circumstances should the drug be used in patients with liver failure cirrhosis of the liver. It should also be taken into account that small child individual intolerance to the drug may develop. After the first application, it is necessary to evaluate the reaction of the child.

Almost everyone is suitable for "Cycloferon" injections. Instructions for use prohibits the use of the medicine only for women during pregnancy. No studies have been conducted in this group of patients. The doctor makes a decision on prescribing a medicine for a nursing mother on an individual basis.

Dosage

It is worth using the Cycloferon remedy correctly. The schedule for children is slightly different. dosage for each dosage form described in the instructions. The most popular medicine is in the form of tablets. They are intended for children over 4 years of age. The kid should be able to swallow the pill, washing it down large quantity water. The tablet should be taken 30 minutes before a meal or one hour after a meal. The dosage depends on the diagnosis. If this is prevention, then a single dose per day will be enough.

With a herpes infection, you should also take the Cycloferon remedy correctly. The regimen for children will be as follows: you need to drink one tablet for 1, 2, 4, 6, 8, 11, 14 days. The course of therapy varies depending on the severity of the infection, the sooner you start therapy, the faster you can get a good result.

How to apply "Cycloferon" injections? Instructions for use for children describe that the drug is administered intramuscularly once a day with a dosage of 150 mg. The duration of therapy depends on the diagnosis.

Liniment "Cycloferon" is advisable to use for herpetic infection. The drug is applied in a thin layer directly to the affected areas. Be sure to evaluate the sensitivity of the patient to the active ingredient. Before starting therapy, a little ointment is recommended to be applied to inner part wrist. If after 10 minutes there is no redness or itching, the medication can be applied to other areas.

If the medicine is used incorrectly, overdose symptoms may occur. it headache, decrease blood pressure, nausea, diarrhea. Often such signs are observed when using drugs in the form of tablets. If the child's health status worsens after the start of therapy, it is worth canceling the medication and seeking additional advice from a pediatrician. What to do so that the drug "Cycloferon" does not harm? Doses for children should be discussed with the attending physician. Even for prevention, it is not worth giving medicine to a child without knowing the features of its use.

special instructions

If a child older than 4 years of age suffers from diseases gastrointestinal tract, it is necessary to give him "Cycloferon" in tablets with caution. A small patient may experience an exacerbation of the disease. You should also consult with an endocrinologist if the child suffers from thyroid disease.

If the treatment is carried out according to a certain scheme and at the same time one dose was missed, a double dosage can be taken again. Interval between separate techniques in this case can be ignored. If within a few days the therapeutic effect is not visible, it is recommended to re-contact a specialist.

How to avoid side effects? It is important to adhere to the dosage described in the instructions. How to drink "Cycloferon" for children is indicated above. The most common side effects include allergic reactions.

drug interaction

How to give "Cycloferon" to a child along with other medicines? Instructions for use indicate that the drug is compatible with all medicines that are used for influenza, SARS, intestinal infections, herpes. Moreover, "Cycloferon" reduces side effects from chemotherapy, as well as interferon therapy. However, this does not mean that any medication can be used without consulting a doctor. It is necessary to discuss the method of therapy of a child with a pediatrician.

Indeed, the drug "Cycloferon" can be called universal. Instructions for use for children confirm this. The medicine is used for many diseases. But to find it, unfortunately, is not possible in every pharmacy. How to choose a quality replacement? You can choose from the medicines described below.

"Anaferon"

This drug also belongs to the category of immunomodulatory. With it, you can quickly overcome a cold, cope with acute respiratory infections and flu. The composition includes antibodies to human interferon gamma. Lactose and magnesium stearate are used as auxiliary components. The drug is available in the form of flat-cylindrical tablets. An analogue of "Cycloferon" for children can also be used for prevention. The medicine helps to activate the immune system. The medication is also used in the treatment of intestinal infections.

The plus is that the drug "Anaferon" can be prescribed from the first days of a child's life. The tablet has a pleasant taste and dissolves easily in the mouth. It needs to be dissipated. If it is necessary to give the drug to an infant, the tablet must first be dissolved in in large numbers water.

The dosage depends on the diagnosis. Treatment of influenza or other acute viral infections carried out using three tablets per day. It is recommended to take them half an hour before meals. If prophylaxis is needed, it is enough to take one tablet before lunch. The course of therapy is determined individually. In most cases, 3-7 days is sufficient.

"Amixin"

This drug is also widely used in colds at babies. The active ingredient is thylaxin, which also perfectly stimulates the defenses of the child's body. The most popular are tablets coated with film sheath. The following elements are used as auxiliary components: potato starch, titanium dioxide, macrogol, polysorbate, quinoline yellow dye. "Amiksin" - effective antiviral agent. The medicine is also widely used in the complex therapy of bacterial infections. However, without consulting a doctor, it should not be given to a child either.

Tilaxin is a substance that stimulates the production of interferon. As a preventive measure, Amiksin tablets, like Cycloferon, can be given to frequently ill children. After oral administration, the drug is rapidly absorbed from the gastrointestinal tract. Therapeutic effect can be seen the very next day after the start of treatment. The drug can also be prescribed as part of the complex therapy of pulmonary tuberculosis.

How is this analogue of Cycloferon taken? Unlike the original, the Amiksin remedy must be drunk after meals. To stimulate the body's defenses, you need to take one tablet per week. Heading dose - 750 mg (6 tablets).

The advantage is that "Amixin" has practically no contraindications. It is not used only during pregnancy and lactation in women. In rare cases, individual intolerance to the components develops.

"Arbidol"

What else can replace the remedy "Cycloferon"? Candles for children "Arbidol" are no less popular, have the same indications. The medicine is also available in the form of capsules. Active ingredient- umifenovir, which stimulates the production of interferon. That is, the drug "Arbidol" also belongs to the category of immunomodulating. The tool easily copes with viruses, helps to restore the body's defenses after suffering bacterial diseases. The drug is used as part of the complex therapy of acute intestinal infections.

How to take the medicine? The medication in the form of suppositories or capsules is given to children, regardless of food intake, 4 times a day. Babies under 6 years of age are prescribed 50 mg, older children - 100 mg each. The course of therapy is determined individually depending on the diagnosis.

Self-medication can be harmful to your health.
It is necessary to consult a doctor, and also read the instructions before use.

Cycloferon: instructions for use

Compound

active substance: meglumine acridone acetate in terms of acridoneacetic acid 150 mg; Excipients: povidone, calcium stearate, hypromellose, polysorbate 80, methacrylic acid and ethyl acrylate copolymer (1:1), propylene glycol.

Description

biconvex tablets yellow color coated with enteric coating.

pharmachologic effect

Cycloferon is a low molecular weight interferon inductor, which determines a wide range of its biological activity (antiviral, immunomodulatory, anti-inflammatory, etc.).

Cycloferon is effective against viruses - herpes-influenza - and - other - pathogens - acute respiratory diseases. It has a direct antiviral effect, suppressing the reproduction of the virus in the early stages (1-5 days) of the infectious process, reducing the infectivity of the viral offspring, leading to the formation of defective viral particles. Increases the body's nonspecific resistance against viral and bacterial infections.

Pharmacokinetics

When you receive daily dose maximum concentration in blood plasma is reached after 2-3 hours, gradually decreases by the 8th hour, and after 24 hours Cycloferon is found in trace amounts. The half-life of the drug is 4-5 hours, so its use in recommended doses does not create conditions for cumulation in the body. Excreted by the kidneys unchanged.

In patients with impaired renal and hepatic function, as well as in elderly patients, a change in the dosing regimen is not required.

Indications for use

adults in complex therapy:

Influenza and acute respiratory diseases;

Herpetic infection.

In children from four years of age in complex therapy:

Influenza and acute respiratory diseases;

Herpetic infection.

In children from the age of four to prevent influenza and acute respiratory infections.

Contraindications

Pregnancy, breastfeeding, children under 4 years of age (due to imperfect swallowing), individual intolerance to the components of the drug, decompensated liver cirrhosis.

Dosage and administration

Inside once a day 30 minutes before meals, without chewing, drinking a glass of water, in age dosages:

children 4-6 years old: 150 mg (1 tablet) per dose; children 7-11 years old: 300-450 mg (2-3 tablets) per dose; adults and children over 12 years old: 450-600 mg (3-4 tablets) per dose.

It is advisable to repeat the course 2-3 weeks after the end of the first one.

In adults:

1. In the treatment of influenza and acute respiratory diseases, the drug is taken on days 1,2,4,6,8 (course of treatment - 20 tablets). Treatment should be started at the first symptoms of the disease. At severe course flu in the first stump take six tablets. If necessary, symptomatic therapy is additionally carried out (antipyretic, analgesic, expectorant drugs). I

2. In case of herpetic infection, the drug is taken on days 1, 2, 4, 6, 8, II, 14, 17, 20, 23 (treatment course - 40 tablets). Treatment is most effective when the first symptoms of the disease appear.

For children over the age of four:

1. For influenza and acute respiratory diseases, the drug is taken in age doses for 1, 2, "

4, 6, 8, 11, 14, 17, 20, 23 days. The course of treatment is from 5 to 10 doses, depending on the severity of the condition and the severity of clinical symptoms.

1. In case of herpetic infection, the drug is taken on the 1st, 2nd, 4th, 6th, 8th, 2nd, 14th days of treatment. The course of treatment may vary depending on the severity of the condition and the severity of clinical symptoms.

2. For emergency non-specific prophylaxis of influenza and acute respiratory diseases (with direct contact with patients with influenza or acute respiratory infections of other etiologies, during an influenza epidemic), the drug is taken on days 1, 2, 4, 6, 8. Then carry out a break of 72 hours (three days) and continue the course for 11,! 4, 17.20, 23 days. The general course is from 5 to 10 receptions.

If the next dose of the drug is missed, then as soon as possible, without taking into account the time interval and doubling the dosage, continue the course according to the started scheme.

Side effect

Allergic reactions.

Overdose

Precautionary measures

In diseases of the digestive system in the acute stage (erosion, stomach ulcers and / or duodenum, gastritis and duodenitis) and a history of allergic reactions, be sure to consult your doctor before taking the drug.