ACC - description, use, dosage and contraindications. ACC: instructions for use, contraindications, indications, side effects, dosage for children syrup, granules, effervescent tablets

ACC is a drug for the treatment of diseases respiratory tract accompanied by viscous, difficult-to-separate sputum. Available from different dosage in the form of effervescent tablets or granules for oral solution. It is prescribed both for the treatment of acute diseases, and for the prevention of chronic conditions of bronchitis and cystic fibrosis. The drug has contraindications, as well as warnings about careful use in various concomitant diseases.

• - glass cup;
• - pure water.

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How to take ACC for children and adults

How to take ACC in order for the drug to work correctly depends on the state of health, weight, age of the patient and other factors that the attending physician pays attention to when recommending the drug. When prescribing a single and daily dosage of ACC, the presence of a disease that requires the use of a drug that thins sputum is important. When a dry cough that occurs during acute respiratory viral infections or acute respiratory infections greatly reduces the quality of life and it is required to quickly transfer it to the wet category, it is recommended to take a mucolytic drug for several days. With cystic fibrosis and chronic forms of bronchopulmonary diseases, the drug can last up to six months. Patients prone to allergic reactions, and conditionally healthy people should take different forms of ACC.

The drug is stored at room temperature not higher than 30 °, and the finished solution can be kept at a temperature of 2 ° to 8 ° for no more than 12 days in a closed refrigerator.

When should the medicine be taken?

The drug has the property of diluting viscous sputum and can be used in the following cases:

1. The ACC drug will be useful for the treatment of acute and chronic bronchitis, pneumonia and other bronchopulmonary diseases associated with difficulty in sputum discharge.
2. The drug is used in the development of acute and chronic sinusitis and exudative otitis media. The active substance is able to thin the viscous mucus that has accumulated in the sinuses, which, after the opportunistic microflora is attached to it, becomes a source of infection. Infected mucus causes inflammation not only in the maxillary sinus, but also causes acute purulent otitis media in the middle ear. Medicinal ACC agent helps to quickly clear the nasal passages from infection.
3. The drug can be used as an antidote for poisoning with aldehydes, paracetamol and phenols.
4. The medicine is not life threatening and is traditionally used in pediatrics. ACC is prescribed for children with cystic fibrosis from the first days of life. With this genetic disease, the drug can be taken for several months without interruption.

Forms of the drug

ACC uses the active substance acetylcysteine, from which the drug got its trade name. It is an amino acid derivative that has a mucus thinning effect. This active substance significantly reduces the viscosity of bronchial secretions. The drug is started after consultation with the doctor.

Acetylcysteine ​​can be given to infants only under the constant supervision of a pediatrician and solely for health reasons. For ease of use, the manufacturer produces the following forms:

1. ACC for children is sold in the form of a powder, which is used to prepare a treatment solution. This form is used for internal reception infants and children under 2 years of age. It does not contain any additives other than the active ingredient. Remedy packaged in 30 g in a 75 ml bottle or 60 g in a 150 ml bottle. The appointment that determines the choice of dose is made by the pediatrician.
2. The drug ACC 100 or 200 for adults is available in the form of effervescent tablets, packaged in 20 pieces. In this form of the drug there are a large number of ingredients to which patients may have individual intolerance.
3. For treatment viral diseases, accompanied by the formation of a viscous secret, to which, after some time, is added conditionally pathogenic microflora, it is best to use ACC hot drink 200 mg. This type of medicine is sold in sachets. They contain a powder that is used to make a hot drink. You need to drink such a drug only hot.
4. ACC 100, like ACC 200, can be in powder form and packaged in double sachets, which are recommended for oral administration to both children and adults. Children under 2 years old are given ACC 100. In this form, in the form of special supplements, there is a minimum amount of supplements. Powder is the most suitable form for all patients prone to allergic reactions.

Drug for the treatment of adults

ACC Long are 600 mg effervescent tablets. They are intended for the treatment of adults who are more comfortable taking the drug once a day. This dosage form can be given to adolescents who have reached 14 years of age. Tablets are sold in a tube with a special lid that prevents moisture from getting inside.

Tablets effervescent ACC Long 600 mg are a popular drug for the treatment of acute respiratory viral infections. In a pharmacy package, there may be 10 or 20 pieces. These are flat-cylindrical tablets with a blackberry odor, which, after dissolving in cool water, form a colorless transparent drug solution with a slight smell of sulfur.

The active substance in each tablet of ACC Long is 600 mg, which is the daily dose of an adult. Of the excipients, the tablet contains the following:

• citric acid;
• sodium bicarbonate;
• sodium carbonate;
• mannitol;
• lactose;
• ascorbic acid;
• sodium cyclamate;
• sodium saccharinate dihydrate;
• sodium citrate dihydrate;
• blackberry flavor "B".

If one of the components is allergic, then the drug is not recommended. ACC Long effervescent tablets are dissolved in cool boiled water in an amount of at least 100 ml. During treatment, it is necessary to provide the patient with a plentiful warm drink. Fluid entering the body large doses, will increase the activity of the sputum thinner.

Long-acting ACC Long tablets are most often used for short-term colds.

Duration of admission should not exceed 7 days.

In chronic bronchitis, the drug can be used long time after the recommendation of the attending physician.

How should the medicine be taken?

ACC in any form is taken one and a half hours after a meal. A dry pharmaceutical preparation is dissolved in 100 ml of cold liquid and drunk. For children and adults, the doses of the drug are different. The disease must be taken into account.

For long-term use in cystic fibrosis in children daily dose depends on the weight of the patient and is determined as follows:

1. For infants weighing less than 10 kg with this genetic disease, ACC for children is recommended.
2. With a weight of 10 to 20 kg, ACC 100 can be used.
3. With a body weight of 20 kg or more, ACC 200 sachets can be used.

For other diseases of the upper and lower respiratory tract, accompanied by the formation of a viscous secret, the daily dose prescribed by the attending physician is divided in equal parts into morning and evening intake:

Treatment of acute diseases with ACC 100 or 200 can last 5-7 days. In the presence of chronic diseases, the drug can be prescribed for long term up to half a year.

What are the side effects of the drug?

Acetylcysteine ​​​​is relatively safe, but in children with an overdose it can cause an increase in secretion and dyspeptic disorders.

When these signs appear, therapy is prescribed taking into account the symptoms that have appeared.

At active substance there are side effects that can worsen the health of an adult or a child. When they appear, you need to stop taking the medicine. About backlash body on the active substance or the additives used in it, it is necessary to inform the attending physician so that he cancels the prescribed remedy and replaces it with another one. The main side effects can be the following:

1. Allergic reactions that occur some time after taking a dose of the drug and manifest as bronchospasm in patients suffering from bronchial hyperreactivity.
2. A rash and itching of the skin may appear a few hours after ingestion.
3. With prolonged use, patients may begin various symptoms from the gastrointestinal tract. The patient may complain of stomatitis, nausea and heartburn. In some cases, vomiting occurs after taking the medicine or diarrhea.
4. Long-term use sometimes contributes to the deterioration of health from the side of the central nervous system. The patient may experience tinnitus and headache.
5. From the side of the cardiovascular system, pressure may rise and heart palpitations may be felt.
6. The drug is not prescribed for hypersensitivity to acetylcysteine ​​or excipients.
7. Fructose intolerance is a contraindication for taking ACC.
8. Acetylcysteine ​​is contraindicated in pulmonary hemorrhage.
9. Pediatricians should not prescribe the drug for hepatitis and kidney failure.

The drug is canceled when a dry cough turns into a wet one, and sputum begins to move away on its own. Abuse of the drug leads to a violation of the natural processes occurring in the bronchi. Most often, the self-cleaning procedure of the respiratory organs is violated.

gidomed.ru

How to use ACC for cough

The drug "ACC" (in Russian more often called ACC), is prescribed for cough in the treatment of colds various types. In addition, the drug is prescribed in the presence of allergic cough spasms, has several forms of release and dosage options, the choice of which depends on the age and weight of the patient. The longest duration of action is distinguished by ACC Long, the effect of which lasts for 12 hours. The last variation of the drug is taken only twice a day.

What kind of cough should I take ACC, dry or wet?

Cough spasms in their types can be both productive, in which sputum is secreted, and dry, most often manifested at the initial stage. colds. Initially, the drug is positioned by manufacturers as a remedy for a wet cough, which helps to remove sputum from the respiratory system and makes breathing easier. However, ACC also helps with dry cough, bringing it to the productive stage.

AT medical practice It is customary to prescribe this medicine in various forms for the following ailments:

It should be borne in mind that the clinical benefit of this drug is possible only if it is used to treat ailments included in the list of those listed above. Thus, you should not try to stop the cough spasm with the help of ACC on your own. If the drug does not give any effect, then most likely the disease does not belong to the profile of its action.

How does the medicine work?

The drug "ACC" is considered an excellent way to deal with sputum that occurs in the cavity of the tract of the respiratory region, lungs and bronchi due to various kinds of infectious lesions. At the same time, sputum, trying to get out for natural reasons, provokes a cough, and often this substance turns out to be too viscous and dense, which leads to its too strong adhesion to the bronchi. With the help of "ACC" it is possible not only to fully establish, but also to advance the process of sputum discharge from the respiratory organs and its removal to the outside.

The main component of the drug is a derivative of cysteine, this amino acid directly affects the structure of sputum, changing its consistency. Mucus increases in its condition, easily detaches from the bronchi and is naturally excreted from the cavity of the respiratory tract. In connection with the removal of sputum, a healing process occurs, and the protective reactions of the mucous membranes are restored.

It is noteworthy that the action of "ACC" is aimed at eliminating not only the usual mucous sputum, but also the one in which purulent formations have already appeared. The drug is often used in conjunction with antibacterial drugs, since it facilitates the penetration of the latter into the mucous membrane of the respiratory system. It is important to observe the two-hour interval between medications. Apart from active action on sputum, cough medicine has antioxidant properties, respectively, acetylcysteine ​​greatly facilitates the course of any viral infection.

In fact, the drug eliminates the manifestation of symptoms characteristic of a severe flu, while simultaneously fighting cough spasms.

Instructions for use of tablets and powder ACC (ass) from dry cough

The correct dosage of the drug is calculated based on the type of ailment for which therapy is carried out, the age and weight of the patient. In addition, the dosages of "ACC" for dry cough for children and adults are different. When treating such a serious illness as cystic fibrosis, the daily dose of the drug is not more than 800 mg, provided that the patient's weight exceeds 30 kg. The duration of therapy can be very long and amount to at least 3-6 months. Treatment should be carried out only under the supervision of a doctor and taking into account the use of a complex of drugs.

For the treatment of dry-type cough spasm in other diseases of the respiratory tract for people over the age of 14, a dosage of 400 to 600 mg of the drug is indicated in the form of tablets or powder consistency at a time. If there is too acute course illness, then taking drugs under the supervision of a doctor lasts at least a week. With a chronic illness, dry cough with the help of tablets or ACC powder can be treated for about six months.

According to the instructions for use, unless otherwise prescribed by the doctor, the drug is taken immediately after meals as an expectorant. The method of taking the medicine is as follows: powder or a certain number of tablets are dissolved in ½ glass of water or tea and drunk immediately.

The medication for children is carried out according to a different scheme, and here important point is the type of drug with respect to the dosage of the active ingredient in it:

1. "ACC 100" is allowed from birth for the treatment of dry cough in infants. The dosage at the age of 2 years is 50 mg three times a day, then the dosage is increased to 100 mg in four doses, and after six years this medication should be taken at a dosage of 600 mg per day, which should be divided into three doses.
2. "ACC 200" is allowed only at the age of a child whose mark has exceeded 6 years, and the use of the drug is allowed only in the form of a solution. Do not use more than two sachets of powder dissolved in water during the course. For adolescents aged 14 years and over, the number of sachets is brought to three, which equals adult dosage.
3. "ACC Long" is allowed only after 14 years, the daily dosage of this type of drug should not exceed 600 mg, and the patient should receive it at one time. The tablet dissolves in water and is taken immediately after a meal inside. The duration of storage of the solution does not exceed half an hour, otherwise the tablet needs to be re-dissolved for a new solution.

Children's cough syrup Ass

For the treatment of cough in children, manufacturers produce a special form of the drug "ACC" in the form of a syrup, the reception and tolerance of which is much lighter than the solution obtained on the basis of tablets or powder. The medicine in this form is also convenient in that it is ready for use and does not require additional dilution steps.

The calculation of the dosage of the syrup is carried out using a measuring cup, and it itself depends on the age and, accordingly, the weight of the child. In particular, 5 ml of the drug is equal to one quarter of a cup.

If the age of the child lies in the aisles from 2 to 6 years, then 5 ml should be taken no more than three times a day. After 7 years, the number of doses increases to 3-4, or it is permissible to use 10 ml at a time, but twice a day. After 15 years, the daily dose is 10 ml 3 times a day. The composition of the drug also has a special syringe for the convenience of calculating the dosage. Its use is very convenient for the treatment of very young children.

Contraindications and side effects

Like any medicine, ACC cough has its own contraindications, failure to comply with which can lead to side effects. According to the instructions developed by the drug manufacturers, it is forbidden to take it in the following cases:

• coughing up bloody mucus;
• bleeding in the lungs;
• fructose intolerance at the genetic level;
• individual intolerance to the main component of the drug and other substances in its composition;
• kidney failure, various diseases liver, especially hepatitis;
• the presence of a peptic ulcer.

As side effects when taking this drug, it is customary to consider such phenomena as various allergic reactions, heart palpitations, heartburn, general violation work from the gastrointestinal tract, which manifests itself in the form of diarrhea and vomiting, headaches and tinnitus.

Allergic reactions are characteristic in the presence of individual intolerance to substances in the composition of the drug, in this case, immediate discontinuation of the drug is required due to the risk of Quincke's edema. In other cases, the study of the medicine did not lead to the identification of any situations in which its use would endanger human life. If any signs of side effects appear, you should immediately stop taking the drug and consult a doctor to adjust the treatment regimen.

The drug "ACC" is successfully used to treat various ailments accompanied by dry and productive cough. The drug and its dosage should be prescribed only by a doctor after the diagnosis.

yadishu.com

ACC instructions for use and description of the drug

ACC is a well-known pharmaceutical preparation based on acetylcysteine ​​as an active ingredient.

From the history of the discovery of acetylcysteine

The honor of the first creation of a mucolytic drug based on acetylcysteine ​​belongs to Professor Ferrari, who worked in the middle of the last century for the Italian pharmaceutical company Zambon. So the first drug was created - Fluimucil. Until now, modern improved forms of this drug can be purchased at pharmacies.

Preparations of the "ACC" group are generics. They are issued after the expiration of the prohibition of the patent holder, are considered analogues. However, there are differences in the composition, which the firm has the right to hide. Produced in Germany and Slovenia.

The effect of acetylcysteine ​​on the human body

In the 50s of the last century, it was noticed that acetylcysteine, Chemical substance close in structure to the protein-cysteine, has the ability to break the bond of mucopolysaccharide molecules that make up the secret of the bronchi, epithelial cells of the paranasal sinuses. This property has been successfully applied in pathological conditions to:

• make more liquid sputum (including purulent) in the bronchi and thick mucus in paranasal sinuses ah nose;
• stimulate increased mucus production;
• activate immune cells (anti-inflammatory effect);
• promote the removal of inflammatory sputum and the cleansing of the bronchi, the removal of mucus from the sinuses through the nose.

Modern studies have shown the ability of acetylcysteine ​​to stimulate the production of phagocytes (killer cells), to destroy free radicals. This achieves the effect of removing liver intoxication with other drugs, an antioxidant effect.

When taken orally, acetylcysteine ​​is rapidly absorbed by the body, the maximum concentration in the blood is reached after 1.5-2 hours. Most of it is excreted through the kidneys with urine, a small amount is removed with feces.

The drug can be used not only inside for the treatment of children and adults. The ampoule form of a 20% solution of 5 ml is indicated for inhalation twice a day, 2 or 5 ml.

For intramuscular and inhalation routes of administration, Fluimucil is prescribed.

Forms of release, differences in composition

In the pharmacy chain, ACC is offered in the form of tablets, flavored granules, syrup for children. The choice of form depends on the age of the patient. It is necessary to study the instructions for the use of analogues. There are convenient dosages of ACC for children 100 mg each, for adults 200 mg each, ACC long 600 mg each. Depending on preference, you can choose a lemon or orange flavor flavor.

When you open a package with granules, a slight sulfurous smell appears, so flavoring additives allow you to get rid of it.

To make it more convenient to navigate, you need, without looking at the annotation of the drug, look at the name indicated on the package. Near the letters is the number "100, 200, 600", indicating the content of the active substance in one tablet or bag of granules. For the treatment of children, it is convenient to buy ACC 100, for adults ACC 200, ACC 600 are suitable.

ACC forms for children

For children, the drug is released in three dosage forms.

• Granules with orange flavor in bottles of 30 and 60 g, boiled water is added to the bottle before use. cold water to the measured line, the bottle is closed and shaken well, a syrup is obtained, it is allowed to store up to 12 hours. The package includes a measuring spoon. The syrup is prescribed depending on the age of the child:

from two to six years - one spoon two to three times a day;

from six to 14 years - one spoon three to four times a day;

adolescents and adults can drink two tablespoons of syrup three times a day.

• Packets with granules ACC 100 or ACC 200 with orange flavor. One packet dissolves in half a glass of water, tea or juice.
• Effervescent tablets. Before taking, they dissolve as well as packets. The solution should be drunk within two hours after preparation.

Adult Treatment

ACC in granules is available in different dosages and differs in flavors:

ACC 100 and ACC 200 3 g each in sachets, except for the dosage of acetylcysteine ​​indicated on the package and in the instructions, contains sucrose and orange flavor;

ACC 200 and ACC 600 also have a honey-lemon flavor in 3g packets. ACC 600 is conveniently taken once a day.

ACC long is prescribed only for adults, it is valid for 12 hours.

The total average daily dose for adolescents and adults is 600 mg. It can be increased by the attending physician. The type of treatment, duration and required dosage are selected by the doctor depending on the severity of the disease, the presence of concomitant chronic diseases.

The general rule for treatment with any analogues is to drink the drug after meals, at the same time it is necessary to consume more liquid (up to two liters per day for an adult), prepare solutions only in glassware.

Indications for use

ACC is used in the treatment of pathological conditions associated with the retention of thick sputum or mucus. These symptoms are seen with:

• chronic and acute bronchitis,
• laryngotracheitis,
• sinusitis of the paranasal sinuses,
• rhinitis
• pneumonia,
• bronchial asthma,
• cystic fibrosis ( hereditary disease).

Also prescribed for the prevention of pneumonia in bedridden patients.

Like all analogs created on the basis of acetylcysteine, ACC in the instructions for use has indications of a weakening of the action of some antibiotics, antitussive drugs, but an increase in drugs containing nitro compounds (used in the treatment coronary disease hearts).

For children under two years old, the remedy is prescribed only for health reasons. Not recommended for the treatment of cough in pregnant women and during lactation.

Caution should be exercised when taking the drug chronic diseases kidneys and liver, peptic ulcer stomach, blood diseases.

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Update: October 2018

ACC (Acetylcysteine) is a drug with an expectorant and mucolytic effect, which is prescribed to thin the viscous secretion of the bronchi in diseases of the respiratory system that occur with the formation of thick, difficult to discharge sputum.

The history of the invention of the drug fell on the middle of the last century. It was then that Professor Ferrari, who worked in the Italian pharmaceutical company"Zambon", found the similarity of acetylcysteine ​​with the protein cysteine, which has the ability to break the mucopolysaccharide molecules that make up the bronchopulmonary secret. The first drug based on acetylcysteine ​​was called Fluimucil.

Farmgroup: mucolytic drug.

Composition, physical and chemical properties, price

ACC is available in the form of tablets (effervescent, soluble), granules and powder for oral administration with different dosages of the active substance. Another one dosage form is a solution for injection (intravenous and intramuscular).

pharmachologic effect

The mucolytic effect of the drug is provided active substance acetylcysteine, which is a derivative of cysteine ​​(an amino acid). The acetylcysteine ​​molecule has sulfhydryl groups in its structure, which contributes to the disruption of the disulfide bonds of mucopolysaccharides in the sputum, which provide the viscosity of the secret. As a result, sputum softens and is easier to separate from the walls of the bronchi.

The drug has a direct effect on the density and rheological properties of sputum, maintaining proper activity even with purulent impurities in the bronchial secret. With the prophylactic use of acetylcysteine, patients with cystic fibrosis and chronic bronchitis note a decrease in the number and severity of exacerbations.

Another effect of acetylcysteine ​​is an antioxidant pneumoprotective effect, which is realized by binding and neutralizing chemical radicals by sulfhydryl groups. The drug accelerates the synthesis of glutathione, an intracellular protection factor against a number of cytotoxic substances and oxidative toxins of internal and external origin, which allows the use of ACC in case of paracetamol overdose.

Pharmacokinetics

Rapidly and completely absorbed, being metabolized in the liver. In the course of metabolic reactions, the pharmacologically active cysteine ​​and a number of other mixed disulfides are formed. Bioavailability is only about 10%. Maximum concentration achieved in the blood 1-3 hours after ingestion. Communication with fiery proteins reaches 50%. Acetylcysteine ​​is excreted by the kidneys as inactive metabolites. The very fast half-life of about 1 hour is due to the biotransformation of the substance in the liver. With liver dysfunction, this period increases to 8 hours.

Indications for use

Diseases of the respiratory system, in which difficult-to-separate, viscous sputum is formed:

• laryngotracheitis;
• bronchitis (acute and chronic);
• bronchiectasis;
• pneumonia;
• obstructive bronchitis;
• lung abscesses;
• bronchiolitis;
• bronchial asthma;
• cystic fibrosis.

Sinusitis (chronic and acute).
Otitis media.

Contraindications for taking ACC

• Exacerbation of GU and duodenum;
• Pulmonary bleeding, hemoptysis;
• Pregnancy and lactation, ACC is prohibited during pregnancy at any time;
• Individual intolerance;

The instructions for the use of ACC for children indicate that treatment is possible strictly according to medical prescription, it is contraindicated:

• Children's age up to 2 years (except for granules for the preparation of the drug in a vial and injections).
• Children's age up to 6 years (granules 200 mg);
• Children's age up to 14 years (granules 600 mg).

It is prescribed with caution to people with pathological varicose veins in the esophagus, at the risk of bleeding from the lungs, bronchial asthma, insufficiency of the liver and kidneys.

Dosage

ACC effervescent tablets 100 and 200 mg

The tablet should be dissolved in water (100 ml) and taken immediately after preparation. In exceptional cases, it is permissible to store the solution for a maximum of 2 hours. Take after a meal, additionally drinking water.

• Children 2-5 years old: One 100 mg tablet or half a 200 mg tablet three times or twice a day (200-300 mg per day).
• Children 6-14 years: One 100 mg tablet or half a 200 mg tablet three times a day. 2nd scheme: two tablets of 100 mg or one tablet of 200 mg twice a day (300-400 mg per day).
• Adolescents from 14 liters and adults: one tablet of 200 mg twice or thrice a day (400-600 mg per day).

In cases of cystic fibrosis, the dose and regimen are different.

• Children 2-6 liters: one 100 mg tablet or half a 200 mg tablet four times a day (200 mg per day).
• Children over 6 liters: two 100 mg tablets or one 200 mg tablet three times a day (600 mg per day).

Patients weighing more than 30 kg are given a daily dose of 800 mg, evenly distributed over doses.

Granules

The instructions for use of ACC powder indicate the method of preparation of the dosage form. Half a sachet or sachet is dissolved in juice, chilled tea or water and the composition is drunk after meals. For syrup drinking water add to the vial up to the mark and shake.

• Children under 2 liters: 50 mg (half a measuring spoon) twice or thrice a day (100-150 mg per day). Strictly prescribed by a doctor!
• Children 2-5 liters: One scoop (100 mg) 2-3 times a day (200-300 mg per day).
• Children 6-14 years: One scoop (100 mg) three times a day (300-400 mg per day).
• Adolescents over 14 years of age and adults: Two scoops (200 mg) twice or thrice daily (400-600 mg per day).

The regimen for cystic fibrosis is similar to tablets.

Syrup

• The syrup is taken after a meal, measuring out the proper amount with a syringe or a glass. 10 ml syrup = half cup or 2 full syringes. It should be taken with water to increase the mucolytic effect.
• Children 2-5 liters: 5 ml of syrup 2-3 times a day (200-300 mg per day);
• Children 6-14 liters: 5 ml of syrup 3 times a day or 10 ml twice a day (300-400 mg per day);
• Children over 14 liters, adults: 10 ml of syrup 2-3 times a day (400-600 mg per day).

For cystic fibrosis:

• Children 2-6 liters: 5 ml of syrup 4 times a day (400 mg per day);
• Children over 6 liters: 10 ml of syrup 3 times a day (600 mg per day).

Injection

It is intended for intravenous or intramuscular administration only in a hospital setting.

• IM: injected deep into the muscle. In / in: diluted with 0.9% NaCl in a ratio of 1: 1, slow administration.
• Children 1-6 liters: 10 mg of solution per 1 kg of body weight.
• Children 6-14 liters: 150 mg (one and a half ml) 1 or 2 r per day.
• Children over 14 liters and adults: 300 mg (3 ml) 1-2 r per day.

Reception duration. Short-term colds: 5-7 days. More severe diseases - for a long time, as directed by a doctor.

Side effects when taking ACC

• CNS: rarely - noise in the head, headache.
• Digestive tract: diarrhea, stomatitis, vomiting, nausea, heartburn.
• CCC: drop in blood pressure, tachycardia.
• Allergies: bronchospasm, which is possible with hyperreactivity of the bronchial system, urticaria and skin rash.
• Occasionally, pulmonary bleeding may develop in people with hypersensitivity to the drug.

special instructions

• The drug should be diluted only in glassware. Upon contact with metals, sulfides are formed.
• Patients with asthma and obstructive bronchitis should be monitored for bronchial patency.
• With the development of any side effects, the drug is stopped.
• Patients with diabetes glucose content should be taken into account: in 100 mg of ACC - 0.006 XE.
• Does not affect the ability to drive a car and work with complex mechanisms.
• Be wary appoint in the pathology of the kidneys, liver.

drug interaction

• It is not recommended to combine acetylcysteine ​​and cough medicines, as this is dangerous by suppressing the cough reflex and sputum stagnation.
• At simultaneous application with nitroglycerin, the vasodilating effect of the latter is enhanced.
• ACC reduces the adsorption of penicillins, cephalosporins and tetracyclines, so antibiotics are prescribed 2 hours after taking the mucolytic.

Analogues

Vicks Active (140-280 rubles)	Fluimucil (150-250 rubles)	Acetylcysteine	Rinofluimucil (nasal) 250 rub.

It is with the help of coughing that the body tries to cleanse itself of mucus and the harmful microbes that are in it in a large number. The faster the body is freed from mucus, the faster the improvement and recovery will come, then the cough will recede. It often happens that the mucus has a very viscous and thick structure, a person coughs, but it does not come out, it bubbles somewhere deep inside. That's when the drug ACC comes to the rescue. MirSovetov decided to tell his readers more about him. You will learn how the drug works, to whom it is recommended and in what cases. Get to know side effects and you will be warned about the diseases and circumstances under which this medicine should not be used.

General information about the medicinal product

This medicine is last years considered one of the best means, helping with coughing, although he has a list of contraindications, conventions and restrictions in the appointment. Given the veneration, fame and positive results, pharmacologists are constantly developing new dosage forms that are more convenient for patients to use. Therapists and pediatricians prescribe it to almost every third of their patients who have complained of an annoying cough. The active ingredient in the drug is acetylcysteine, and this formed the basis of the abbreviation name - ACC. it chemical compound- a derivative of the well-known amino acid - cysteine. Getting into the sick body of a person who is already tired of coughing, it can work wonders. In most cases, in such patients, very thick and viscous mucus (sputum) stagnates in the airways, preventing the air flow from circulating, constantly irritating the mucous membranes, thereby causing bouts of prolonged coughing. Moreover, such a humid environment serves as a good basis for the further reproduction of pathogenic microorganisms. A vicious circle, as a result of which the disease takes on a protracted character. The worsening symptoms are more and more disturbing, especially at night, for the patient and his relatives. It is in such cases that acetylcysteine, which is classified as a mucolytic and expectorant, is suitable for treatment. This group drugs has the ability to thin the mucous exudate and facilitate its evacuation from the respiratory tract. In addition to ACC, the group of mucolytics includes Bromhexine, Ambroxol, a syrup obtained from licorice root.

How does the medicine work?

Acetylcysteine ​​acts on thick mucus at the molecular level. In this case, the bonds between sulfur atoms are destroyed (they are also called disulfide bridges). It is these bonds that give sputum increased viscosity. Thanks to ACC, the secret becomes more liquid and fluid, it is easier for him to leave the lungs and airways. ACC particles destroy the integrity of viscous components called mucopolysaccharides. Now the sputum is able to move outward along the bronchial tree to the side oral cavity. Cough at first becomes more wet, productive, a person spits out sputum. Gradually, the cough disappears, having fulfilled the function assigned to it by nature. Acetylcysteine ​​also has an antioxidant property, having a beneficial effect on local inflammatory process flowing in the bronchi.

When is ACC appointed?

The drug is indicated for all diseases, which are characterized by pathological accumulation of thick exudate (sputum) in the lungs, bronchi and other parts of the respiratory system:

• bronchiectasis;
• obstructive, chronic and acute bronchitis;
• COPD (as doctors call chronic obstructive pulmonary disease for short);
• bronchiolitis, pneumonia;
• in acute and chronic stage;
• , tracheitis, ;
• exudative otitis;
• (MirSovetov recently told his readers about this disease).

Dosage

In the pharmacy, you can find ACC in the form of sachets with granular powder, effervescent tablets, injection solutions (intramuscular, intravenous and drip infusions). Numbers are also indicated on the packages next to the name: 600, 100, 200 - this is the number of milligrams of the active substance in one sachet or effervescent tablet. For example, ACC 100 means that the sachet contains 100 mg of acetylcysteine. If there is an inscription "LONG", then this means that the dose of acetylcysteine ​​in a tablet is 600 mg, this amount is taken once a day, the drug has a prolonged (extended) effect. An effervescent tablet or the contents of a sachet (granular powder) must be dissolved in 100 ml of water before taking. Children are allowed to use fruit juice, milk instead of water. The liquid may be warm, but not hot. It is better to take ACC after a meal. On the days of treatment, try to drink more liquids, mineral waters (for example, Borjomi) - all this helps to enhance the therapeutic effect of acetylcysteine. And now for the dosage:

1. Adults and adolescents who have already reached the age of 14 should take from 400 to 600 mg of the drug per day. The dose should be divided into two or three doses. If you bought the drug at 600 mg, then you need to drink it once.
2. If a child is from 6 to 14 years old, then he is given 100 mg of medicine three times a day.
3. For children from 2 to 5 years old, ACC is given 100 mg twice a day, in rare cases it is taken three times.
4. Babies under two years of age are allowed to drink ACC only as prescribed by a pediatrician, then the dose can be 50 mg two or three times a day.

Doctors usually recommend drinking the drug for five or seven days with a cold. With bronchitis, the course is longer. But with cystic fibrosis, the doctor individually decides how the patient should take ACC, it all depends on the severity of the condition and the form of the disease.

Are there side effects?

Undesirable effects while taking ACC occur, but are rare. And yet MirSovetov will call them:

• , vomiting, stool disorders (in the form of diarrhea);
• blood pressure may drop for a short time;
• dizziness, tinnitus;
• increased heart rate;
• urticaria, itchy rash, bronchospasm (in predisposed people).

When should the drug not be used?

The manufacturer warns that acetylcysteine ​​is contraindicated in the following cases:

• with pulmonary bleeding and hemoptysis;
• if the ulcer in the gastrointestinal tract has become aggravated;
• in case of individual intolerance and hypersensitivity of a person to the components of the drug.

Caution should be taken when taking the drug for those who suffer from serious disorders of the kidneys, adrenal glands or liver, bronchial asthma with hypersecretion.

There is very little data on how ACC affects the fetus and pregnant woman, so it is better to avoid taking the drug during pregnancy and during breastfeeding newborn.

special instructions

If you are taking nitroglycerin, then you should remember that ACC enhances its vasodilating effect.

It is incompatible to take ACC simultaneously with antibiotics, representatives of the groups of semi-synthetic penicillins, tetracyclines, aminoglycosides and cephalosporins. Therefore, when buying an antibiotic prescribed by a doctor, be sure to ask the pharmacist at the pharmacy which group this antibiotic belongs to. If this is a representative of the above groups, then 2 hours must pass between taking this remedy and ACC, then no conflict between the drugs will occur.

When buying, also pay attention to the fact that the bag may say that it is used to make a hot drink. Such granules must be dissolved in a hot liquid.

It is necessary to dissolve ACC in a glass dish, avoid contact of the medicine with metal, a wooden stick or a small porcelain spoon is suitable for stirring.

These are the properties of the popular medicine ACC. If you follow all the recommendations and doses, taking into account special instructions, it will improve the excretion of sputum and help get rid of a bothersome cough.

Among the mucolytic drugs prescribed for coughing, the ACC medicine manufactured by Sandoz is in great demand. Can it be used in the treatment of children and at what age is it permissible to give ACC to babies? What is the best dosage form for childhood? How to dilute a tablet or granules? These and other questions about the use of such a medicine are of concern to every mother if the doctor has prescribed this drug to her coughing child.

Release form

The ACC preparation is presented in the following forms:

1. Effervescent tablets. They are flat round shape, blackberry smell and white color, and the content of the active ingredient in each soluble tablet is 100 or 200 mg. Tablets with 600 mg of the active compound are also produced, called ACC long. One tube includes 10-20 tablets.
2. syrup. The packaging of such an ACC is represented by a glass bottle filled with 100 ml of a transparent, colorless, viscous liquid with a cherry aroma. 1 ml of syrup contains 20 mg of the active ingredient.
3. Packets with granules. The weight of one sachet is 3 grams, and one pack includes 20 sachets, inside of which there is a white homogeneous granular powder. A drink made from it can taste like orange or lemon with honey. The content of the active ingredient in the package is 100 mg or 200 mg.
4. Solution. Such a medicine, called ACC injection, is represented by a clear liquid without any color, poured into 3 ml ampoules. One ampoule contains 300 mg of active ingredient. One package includes 5 ampoules.

The main ingredient of any form of ACC, which provides the drug healing effect is acetylcysteine. Excipients in different types of medicines differ:

• Effervescent tablets contain citric and ascorbic acid, bicarbonate, saccharinate, citrate and sodium carbonate. Also in this form is milk sugar and mannitol, and the blackberry flavor gives a pleasant smell to the tablet and the solution prepared from it.
• Auxiliary ingredients of the ACC powder form are sucrose and ascorbic acid. Also, this medicine contains saccharin, and the presence of flavoring makes the drink prepared from the granules orange or lemon-honey.
• Additional substances in the syrup are represented by water, methyl parahydroxy benzoate, disodium edetate, as well as hydroxide, carmellose, benzoate and sodium saccharinate. The smell of this medicine gives cherry flavor.
• In addition to the active substance, the ACC solution contains sterile water and disodium edetate. Also, this liquid form contains ascorbic acid and sodium hydroxide.

Operating principle

After entering the human body, acetylcysteine ​​begins to directly affect the sputum formed in the respiratory tract. In particular, this compound alters the rheology of mucus by breaking bonds in mucopolysaccharides found in bronchial secretions. This thins the mucus and reduces its viscosity. The effectiveness of the remedy does not fall, even if pus is mixed with mucus.

Acetylcysteine ​​also has some antioxidant activity. It is noted that this substance stimulates the synthesis of glutathione, and is also able to neutralize the radicals formed during oxidative processes. This action of ACC strengthens the protection of the cells of the respiratory tract mucosa, and also helps to reduce the inflammatory process.

Indications

The reason for the use of ACC is any disease of the respiratory system, in which inside bronchial tree accumulated too viscous secret.

The drug is prescribed for:

• Laryngitis.
• Bronchitis.
• Pneumonia.
• Laryngotracheitis.
• Chronic pulmonary pathologies, including those with obstructive disease.
• bronchiolitis.
• bronchiectasis.
• Development in the lung abscess.

ENT doctors prescribe such a medication for otitis media, rhinitis or sinusitis. Helps ACC and cystic fibrosis.

At what age can you give?

Instructions for use allow the appointment of ACC for children who are 2 years old. For young patients aged two to 5 years, a medicine called ACC 100 is intended, since the dosage of the active substance in it is the lowest. Preparations ACC 200 and ACC injection are prescribed for children six years of age and older. Medication with maximum dosage acetylcysteine ​​(ACC long) is recommended from the age of 14.

Contraindications

Annotation to ACC preparations prohibits their use in such cases:

• If a child has an intolerance to some component of the drug, for example, acetylcysteine ​​or lactose, which is in the composition of the tablets.
• If the lung disease is complicated by bleeding and traces of blood are found in the sputum.
• If the patient has a peptic ulcer.
• If the child suffers from a lack of certain enzymes (lactase, sucrase) or impaired carbohydrate metabolism.

Without consulting a doctor, ACC should not be given to children with bronchial asthma, arterial hypertension, kidney disease, liver pathologies, adrenal dysfunction, and diabetes mellitus. With such diseases, the pediatrician first evaluates the indications, and then selects the desired form of ACC and correct dosage drug.

Side effects

Like many other drugs, ACC can cause allergies. From taking such a medication, hives, swelling of the skin, itching, rashes, and even anaphylactic shock may occur.

Other side actions of ACC there are:

• Shortness of breath or the appearance of bronchospasm. Such a reaction child's body on acetylcysteine ​​is often found in bronchial asthma. If a child has an increased cough after taking ACC, you should immediately consult a doctor.
• Heartburn, loose stools, discomfort in the stomach and other symptoms that are called dyspepsia.
• Increased body temperature, headache, noises in the ear, bleeding. Such negative effects ACC treatment are very rare.

Instructions for use How to take

• The use of ACC is recommended after meals.
• An effervescent tablet in the right dose should be lowered into a glass of water, wait for dissolution, and then offer the medicine to the child. For dissolution, only water and glassware are used.
• The contents of the ACC portion sachets are dissolved in half a glass of liquid. At the same time, the granules can be diluted with both water and another drink, for example, juice or cooled tea.
• It is undesirable to leave the suspension prepared from a tablet or ACC powder for a long time. If it is not possible to drink the medicinal solution immediately, it is permissible to store at room temperature for no longer than two hours.
• For dosage of syrup, it is advised to use a measuring cup or syringe, which is placed in the medicine package.
• The last intake of ACC should not be later than 18 hours, since more late application can negatively affect sleep.
• To therapeutic effect the drug came faster, an additional intake of a large volume of liquid is recommended.
• How many days to take the medicine, the doctor decides for each child individually. In acute illness, the duration of use is most often 5-7 days.
• ACC injections are done in the hospital 1-2 times a day. The drug is injected either deep into the muscle or slowly into the vein (within 5 minutes), mixing the contents of the ampoule with saline or glucose in a ratio of 1 to 1.

Dosage

The daily dose of ACC, regardless of the form of release for the child different ages will be like this:

This dose is divided into 2 doses for children under 14 years of age, and a child over 14 years of age can be given the drug either once a day or divided into 2-3 doses.

single dose different forms ACC for a child older than 2 years to 6 years of age is usually 100 mg of acetylcysteine.

A child of this age is prescribed one of these drugs:

A single dosage for children older than 6 years to 14 years of age will be 150-200 mg of acetylcysteine. Often, the drug is prescribed in a dosage of 200 mg per dose.

Depending on the form of ACC, this will be the following amount of medicine:

At the age of 14 years and older, the daily dose of ACC may be:

single dosage injection form ACC is half an ampoule for children 6-14 years old and a whole ampoule for a child over 14 years old. In the presence of vital indications, the drug can also be administered to children under 6 years of age at a dosage of 10 mg of the active substance per 1 kg of the baby's weight.

ACC solution in ampoules can also be used for inhalation in a nebulizer. For one procedure, take 3 ml of medication and mix with 3 ml of saline. Such manipulation is allowed when coughing in children over 12 years old.

Overdose

Taking too much ACC leads to vomiting, severe nausea or loose stools. To help with an overdose, the doctor prescribes symptomatic treatment.

Interaction with other drugs

• Mixing in one glass of ACC and any other drugs is not recommended.
• The use of sorbents, for example, activated carbon, will reduce the effectiveness of acetylcysteine ​​treatment.
• Categorically it is impossible to give children ACC and drugs that suppress the cough reflex. This combination of medications can cause congestion of mucus in the airways.
• If you combine ACC and drugs from the bronchodilator group, then cough treatment will be more effective.
• Acetylcysteine ​​may worsen the effect of antibiotic therapy if cephalosporins or penicillin drugs are used, and therefore a break of 2 hours or more should be taken between such drugs.
• The simultaneous administration of ACC and vasodilator drugs leads to greater vasodilation.

Terms of sale

To purchase any form of ACC, except for injection, you do not need to present a prescription. To purchase ACC Inject, you will need a prescription from a doctor.

On average, the cost of a pack of 20 ACC 100 tablets or one bottle of syrup is about 240 rubles. The price of ACC in bags is approximately 120-130 rubles per package. For ten tablets of ACC long, you need to pay about 300 rubles.

Storage conditions and shelf life

Keep ampoules, granules or tablets in a dry place out of reach for a small child. Storage temperature should not exceed 25 degrees Celsius. When removing a tablet from a tube, the package must be immediately closed tightly.

The shelf life of the drug, depending on the form, is:

• For tablets - 3 years.
• For bags with granules - 4 years.
• For syrup - 2 years (not opened).
• For ampoules with a solution - 3 years.

When the bottle of ACC syrup is opened, the medicine should be stored no longer than 18 days.

On the use of ACC for wet cough in children, there are mostly positive reviews. Moms confirm that the drug is very effective in thinning a very viscous secret and helping to cough up, thereby speeding up recovery. Side effects from ACC are rarely noted, and the taste of the finished medicine is considered pleasant by most children.

Analogues

Any analog, which also contains acetylcysteine, is capable of replacing ACC. Such a drug may be Fluimucil, N-AC-Ratiopharm, Acetylcysteine ​​or Acestine. With a runny nose, you can use the drug Rinofluimucil, which also includes acetylcysteine. The medicine is released in the form of a spray, which is convenient to inject the medicine into the nose.

• Lazolvan. The active substance of such an expectorant is ambroxol. The advantages of Lazolvan are big variety dosage forms and the possibility of use from birth.
• Erespal. The basis of this drug is fenspiride, which has antihistamine action. Reception Erespal relieves bronchospasm and helps in the fight against inflammation, so this medicine is in demand for dry and barking cough. In syrup, it is prescribed from the age of two, and in tablets - not earlier than 18 years.
• Fluditec. Such a mucolytic contains carbocysteine ​​and is available in syrup with two dosages. The smaller one (20mg/ml) allows the use of the medicine from 2 years of age, and the larger one (50mg/ml) is allowed from the age of 15.
• Gedelix. This plant-based remedy has an expectorant effect. The drug is made from ivy leaves in syrup and drops. It can be given to children who are 2 years old.
• Mukaltin. This expectorant medicine in tablets is prescribed for children older than a year.
• Ascoril. Such multicomponent drug contains salbutamol and bromhexine, which are supplemented with guaifenesin. Its reception dilutes the secret of the bronchi and has an expectorant effect. This medicine in syrup is prescribed for children from 1 year old, and the tablet form - from the age of six.

Cough is one of the symptoms that occurs in diseases of the respiratory tract. It serves as a natural defense mechanism organism.

In fact, this is the process of cleansing the respiratory organs of mucus, the amount of which increases during the illness.

When a child coughs, parents worry about him. There are many remedies for this symptom. If it is a wet cough that worries you, ACC for children helps a lot. It is popular, affordable and safe. Due to the variety of forms, it is suitable for the treatment of children and adults of any age, with a number of diseases. Consider in this article: what and how this medicine treats, its release forms, ACC instructions for children, analogues and reviews.

What does acetylcysteine ​​treat?

The medicine is intended for the treatment of wet cough. The active ingredient in this medicine is acetylcysteine. It liquefies mucus, causing it to be withdrawn from respiratory tract and prevents inflammation.

Phlegm is a large amount of mucus produced during an illness. It's called a secret. The secret provides airway protection, cleansing and fights bacteria.

The ACC instruction prescribes the use of the drug in children with the following diseases:

• various bronchitis;
• bronchiectasis;
• cystic fibrosis;
• tracheitis;
• laryngitis;
• various sinusitis;
• pneumonia;
• otitis.

Mechanism of action

Once in the respiratory tract, acetylcysteine ​​changes the structure of the secret. This substance breaks the bonds of mucopolysaccharides, which makes the mucus more liquid.

Acetylcysteine ​​is an antioxidant. It activates the release of glutathione, otherwise known as the "mother of all antioxidants". The radicals formed during oxidation are neutralized by acetylcysteine.

After taking this medicine, the removal of sputum from the respiratory tract is simplified. Air begins to circulate freely in the respiratory organs. The cough becomes easy and effective.

Method of use for cough

There are several forms of the drug:

1. In syrup. It is viscous, transparent with a cherry flavor. Produced in a dark glass bottle with a white cap and a dense membrane. Added a protective ring against opening by children. The kit includes a measuring syringe with a volume of 2.5, 5 ml and a metered cup for 2.5, 5, 10 ml. 1 ml contains 20 mg of the main substance.
2. In white round and flat tablets, soluble in water. The main component in each of them is contained in a volume of 100 mg or 200 mg. ACC long contains 600 mg of the main element.
3. Powder bags. One package contains 20 bags of white powder. May have an orange or lemon flavor. The sachet contains 100 mg, 200 mg or 600 mg of the main substance.
4. In the form of a solution. This species is available in ampoules and is used for injection. One contains 300 mg of the main component.

Instructions for use for children

Although the drug is over-the-counter and safe, it must be prescribed by a doctor. Only a professional is able to accurately determine the patient's condition and choose the right type and dose. Consider important questions that are covered in the instructions for use of ACC for children.

At what age can a child be given?

From what age can children's ACC be used - it is written in the instructions. The medicine is intended for patients from the age of two. For babies aged 2 to 5 years, ACC 100 is suitable, because the content of the main component in it is minimal.

With the help of ACC 200 and ACC injection, patients are treated from the age of 6 years. ACC long is prescribed to patients from 14 years of age, since the content of acetylcysteine ​​in it is the highest.

Is it possible for children under one year old?

Reception of ACC for children under the age of one year is prescribed only under medical supervision in the hospital. respiratory organs and pectoral muscles in babies are poorly developed. They are unable to cough up large amounts of mucus.

How to use?

The following rules speak about how to take children's ACC:

• put effervescent tablets in a glass with water and stir, then give the patient the medicine to drink;
• granular powder must be dissolved in a half-filled glass of water;
• the finished medicine from pops or granules must be drunk for two hours, otherwise it loses its properties;
• in order to correctly measure the desired dose of syrup, it is better to use the supplied syringe or cup;
• ACC is not recommended for a child 4 hours before bedtime, so effective excretion sputum requires active coughing, which is either impossible in a dream, or will prevent the child from sleeping;
• it is recommended to drink more water during treatment with this drug;
• in acute diseases, the doctor should prescribe the duration of the drug;
• by injection, the drug is administered in the hospital intramuscularly or into a vein 1-2 times a day.

Dosage

When taking ACC for children, the following dosage is used:

1. Children from 2 to 6 years old - 200-300 mg of the main component. For taking the drug at this age, the dose is divided into 2-3 times. It is prescribed in this form and amount of the drug:

• 1 pop ACC 100;
• 1 sachet ACC 100;
• syrup 5 ml.

1. Patients from 6 to 14 years old - 300-400 mg. The dose of ACC for cough for children of this age is 150–200 mg of the main component. In various forms, the dose is as follows:

• 2 packages of ACC 100;
• 1 sachet ACC 200;
• 1 pop ACC 200;
• 2 pops ACC 100;
• syrup 10 ml.

1. Patients over 14 years old - 400-600 mg. There are 3 ways to use ACC for children of this age - 1-3 doses per day. AT various types the drug is taken based on the following rules:

• 2–3 packages of ACC 200;
• 4–6 sachets of ACC 100;
• 2–3 pops ACC 200;
• 4–6 pops ACC 100;
• syrup 20–30 ml.

These are standard doses of medication. In case of especially acute and serious diseases, an increase in dosage is allowed.

Before meals or after?

Taking ACC before meals is not recommended for children - the medicine should be taken after meals. Immediately after the end of a meal or for some time after it. This requirement is explained by the aggressive nature of acetylcysteine ​​in relation to the digestive system.

Important information for parents

Before giving ACC to children for coughing, parents should be aware of the contraindications:

• can not be used for ulcers;
• with intolerance to the main component or lactose;
• with bleeding from illness.

It is necessary to consult a doctor about taking the drug for such diseases:

• diseases of the kidneys and adrenal glands;
• liver disease;
• asthma;
• arterial hypertension.

Do not mix the drug with others, especially with cough suppressants and with some antibiotics.

What reviews does the drug receive?

Mostly there are laudatory reviews about ACC. For children and themselves, parents purchase this drug and write, most often they say that the remedy really helps with a number of diseases - bronchitis, pneumonia, sinusitis and others. In particular:

• cough is relieved and stops after a short time (when using ACC as part of antibiotic therapy);
• disappear pain in the chest and in all respiratory organs;
• some use the drug to relieve coughing when smoking.

Children and adults drink it with pleasure, as there are flavoring additives in the medicine. Often they write that the medicine is similar in taste to lemonade, compote, mineral water with additives or tea. Side effects occur sometimes, but they can be caused by non-compliance with the rules for taking the drug, the recommendations of doctors. For example, they learn how to properly prepare azz for children: before meals or after, forgetting that it should be given to patients only after meals.

ACC powder 100 mg

This type of ACC is good for children. The granules contain the following substances:

• acetylcysteine;
• sucrose;
• vitamin C;
• saccharin;
• orange flavor.

Children's syrup

Children's ACC in the form of a syrup is intended for the treatment of children over the age of two years. Has the following composition:

• acetylcysteine;
• water;
• 10% aqueous solution;
• sodium carmellose;
• sodium saccharin;
• methyl parahydroxybenzoate;
• edetate disodium;
• cherry flavor.

To use the syringe, you need to perform the following sequence of actions:

• read the instructions and remove the cover as indicated in it;
• insert the plug from the syringe into the container until it clicks;
• insert the syringe tightly into the vial;
• turn the container over and draw the desired amount of liquid;
• remove the syringe from the vial;
• slowly put the syrup into the child's mouth;
• don't forget to rinse the syringe.

Effervescent tablets 100 mg

ACC for children in tablets is also intended for the treatment of patients over the age of two years. They have the following composition:

• acetylcysteine;
• bicarbonate;
• sodium carbonate;
• vitamin C;
• lemon acid;
• sodium citrate;
• sodium saccharin;
• mannitol;
• lactose.

Analogues

ACC for children has several analogues. These include the following medications:

• Fluimucil. It is produced in Switzerland. Similar in composition to its content of the main active ingredient. Available in three forms: powder, solution for injection and effervescent tablets. Has flavors.
• Acetylcysteine. It is produced in the form of a white powder with a yellow tint and in the form of pops. It is also used for wet cough from diseases such as bronchitis, tracheitis, pneumonia, cystic fibrosis and others.
• Vicks Active Expectomed. Produced in the form of round and flat pops in white. Has a lemon flavor.
• Lazolvan. The main component of this medicine is ambroxol. Advantages of the drug: variety and the ability to prescribe it to children from the first years of life.

Useful video

How to quickly cure a cough in a child? See useful information in the next video:

Conclusion

1. The drug considered in the article must be used for treatment correctly: follow all the rules according to the instructions, treat the child only after consulting a doctor. Only then will the drug serve as a wonderful remedy for a wet cough.
2. It is not necessary to treat a child without professional diagnostics of doctors and prescribing a certain course. Be aware that side effects are possible.

ACC syrup for children is one of the drugs of choice for acute and chronic bronchopulmonary diseases in young patients. The medicine helps to improve the process of sputum discharge.

Despite the fact that the remedy is mainly effective in infectious respiratory diseases, it is used in complex therapy some congenital pathologies.

How is it different from others? How to take? To answer questions, you should familiarize yourself with the properties of the drug in more detail.

Pharmacological action According to the mechanism of influence on the bronchial secretion, children's ACC syrup belongs to mucolytics. It destroys the disulfide bonds between the protein molecules of the mucus, making it less viscous and "sticky" (adhesive) in relation to the respiratory mucosa.

Has an antioxidant effect. Increases the resistance of cells to damaging reactions of free radical oxidation, characteristic of severe inflammation.

Another rather important property is not indicated in the official instructions. Acetylcysteine ​​blocks the toxic effect of paracetamol. It plays the role of an antidote for overdose of this medicine.

The active substance is acetylcysteine. It has been known in medical practice since the 1960s. 1 ml of the drug contains 20 mg of the active ingredient.

Produced in the form of syrup with a cherry flavor. To increase the shelf life, it is placed in dark glass bottles.

Does not contain ethyl alcohol and dyes. In the pharmacy you can buy volumes of 100 ml or 200 ml.

The bottle has a system of protection against opening by children. For convenient dosing, a graduated measuring cap (10 ml) and a syringe (5 ml) are included. Each of them is labeled to determine the volume.

What are the features?

Cough syrup for children ACC differs from some mucolytics. Therapeutic effect it develops faster than ambroxol (Lazolvan, Ambrobene).

This is due to the direct splitting effect on sputum, which has already formed. Ambroxol has a greater effect on the process of mucus formation, so the mucolytic effect develops somewhat more slowly.

It is impossible to say that acetylcysteine ​​is more effective than ambroxol. The converse statement is also incorrect. For each specific situation, a different mucolytic is preferred.

The main goal is to reduce the viscosity of the mucous secretion. Therefore, acetylcysteine ​​solution helps with coughs with thick, difficult to separate sputum. Effectively liquefies even pus.

Reduces nocturnal cough in a child with bronchitis. But you should remember the general rule for mucolytics: they should not be given after 18.00. If consumed just before bedtime, thinning sputum, on the contrary, will cause a coughing fit.

With rhinopharyngitis, ACC will not remove the cough from the "snot" in a child on its own. Even if it is possible to reduce the viscosity of the mucus, its production in the nasopharynx will not stop. Without complex treatment it will continue to flow down and irritate the respiratory mucosa.
Source: nasmorkam.net to content?

ACC in syrup for children: for what diseases?

• Bronchitis. Effective in chronic and acute inflammation. It can be prescribed for obstructive bronchitis, accompanied by blockage of the bronchi due to swelling of their mucous membrane.
• Inflammatory diseases of the larynx and trachea. We are talking about laryngitis, laryngotracheitis.
• Pneumonia is an inflammation of the lungs.
• Cystic fibrosis is a hereditary disease that affects all glands external secretion and the formation of thick, viscous sputum.
• Lung abscess - limited area purulent inflammation in organ tissue.
• Diseases with changes in the structure of the walls of the bronchi. With bronchial asthma, COPD (chronic obstructive pulmonary disease). It is indicated for bronchiectasis - deformation, expansion of the walls of the respiratory tract with chronic suppuration in them. In the treatment of bronchiolitis - inflammation of the terminal branches of the bronchial tree.

The official instructions for the use of the drug indicate that it is prescribed not only for pulmonary diseases. For example, an oral solution is suitable for the complex treatment of sinusitis: it thins the mucus in the paranasal sinuses, helping to cleanse them.

The drug has found use in the treatment of inflammation of the middle ear. It prevents blockage of the auditory tube with mucus.

Do not use in case of hypersensitivity to any of the components of the drug. It is not recommended to take during exacerbation of gastric and duodenal ulcers. It is not prescribed in the presence of hemoptysis, signs of pulmonary bleeding.

Pregnancy and breastfeeding

Despite the label "for children", the medicine is often tried by adults. It should not be taken during gestation. The doctor may prescribe the drug, but only after the balance of benefits and risks. During treatment, you can not breastfeed.

Carefully

Particular attention should be paid to the use against the background of pathologies. digestive system: peptic ulcer of the stomach and duodenum, varicose veins of the esophagus, liver failure. Strict control of a specialist is necessary for pathologies of the kidneys and adrenal glands, arterial hypertension.

Acetylcysteine ​​affects the metabolism of histamine (an inflammatory mediator). Therefore, if it is intolerant, a long treatment course is not recommended.

Bronchial asthma is included in the list of indications, but with caution. If, after use, signs of suffocation suddenly appear, a severe paroxysmal cough in a child, the syrup should be canceled and a doctor should be consulted to correct therapy.

Possible side effects

Like other medicines, it can cause allergies. In isolated cases, it causes anaphylactic shock.

Individual list side effects extensive, but they occur infrequently or even very rarely. Possible consequences:

• Skin changes. May be disturbed by itching, rashes, urticaria. Quincke's edema is possible. There is a danger of toxic epidermal necrolysis - the death of the cells of the outer layer of the skin. Occurs very rarely.
• Disorders in the work of the cardiovascular system. Very rare (against concomitant pathology) may bleed. Infrequently, arterial hypotension occurs.

• Disorder of the respiratory tract. Rare side effects include shortness of breath and bronchospasm.
• Gastrointestinal disorders. Nausea, up to vomiting, may occur. Infrequently worried about abdominal pain, loose stools.
• Hearing loss. Sometimes there is noise in the ears.
• General violations. Infrequently worried about headache, hyperthermia, swelling of the face. Platelet aggregation may decrease (additional risk of bleeding).

The presence of any of the side effects is the basis for contacting a treating specialist. If necessary, he will adjust the dosage or replace the medication.

The number and frequency of administration depend on individual indications. Dosage for children is determined by age.

As a mucolytic, patients from 14 years of age are prescribed 10 ml up to 2-3 times a day. The maximum daily dose is 400-600 mg of the active substance.

Children 6-14 years old are shown 5 ml per day three times. For convenience, the dosage can be changed: for example, 10 ml in the morning and in the evening. The maximum daily amount of the active ingredient should not exceed 300-400 mg.

From 2 to 5 years, 5 ml is prescribed 2-3 times a day. The average daily amount should be 200-300 mg.

In cystic fibrosis, they try to prescribe as much as possible daily doses. Children from 6 years of age are shown 10 ml three times, or 600 mg per day. From 2 to 6 years: 4 times 5 ml, or up to 400 mg per day.

Can it be used up to 2 years?

The dosage prescribed for a one-year-old patient is not indicated in the annotation due to the presence of contraindications. Self appointment such a patient is fraught with suffocation, aggravation of the overlap of the bronchi with mucus. This is due to age-related imperfection in the development of the respiratory tract.

More than 34 international studies have been conducted involving more than 2000 children from 2 months. ACC was well tolerated, with its administration, no increase in the phenomenon of "swamping of the lungs" was recorded. But the comparison was not with a placebo (dummy drug), but with mucolytics.

This means that against the background of the action of the syrup, the risk of stagnation of liquid sputum in the lungs in children under 1-2 years of age remains. It's just that the percentage is not higher than that of other mucolytics. The remedy at this age is given only with the permission of the doctor and under his close supervision.

Instruction baby syrup ACC contains general recommendations. The final treatment regimen is approved by the attending physician.

How many days to give ACC syrup?

At respiratory infections, on average, it takes 5-7 days. Maximum effect achieved within 3 days. In cystic fibrosis, it is used for a long time, in order to prevent exacerbations.

Take before meals or after?

Should be drunk after meals. Additional fluid intake increases the mucolytic effect.

ACC syrup or powder: which is better?

You can buy granules in individual sachets of 100 mg. This dosage form is approved by the Russian Union of Pediatricians. The dosing principles are identical, so there are no differences in terms of the amount of active substance.

Some parents are uncomfortable with measuring cups and syringes: they are afraid to make a mistake with the volume, accidentally spill the solution. Granules in bags will greatly simplify the task. In a number of situations, on the contrary, if the child does not yet know how to use a mug, it is easier to drink it from a syringe.

What to choose? There is no single answer. Syrup and granules are not inferior to each other in terms of effectiveness. It is better to give preference to the form that the child likes and is most convenient for swallowing.

There was no intoxication when using 500 mg/kg of body weight. In case of an overdose, nausea, vomiting, diarrhea are possible. Antidote is not required, treatment is symptomatic.

ACC syrup for children, if necessary, can be replaced by synonyms with the same active ingredient. There are relatively cheap options, but in general the cost is approximately the same. Examples:

• Fluimucil. With identical dosage of the active substance. Used from 2 years old. For the treatment of ENT diseases, a combined spray Rinofluimucil was created.
• Acetylcysteine ​​from MARBIOPHARM. Produced in granules with a citrus flavor.
• Acetylcysteine ​​Canon. It is produced in the form of a powder (100/200 mg in one sachet), granules (200/600 mg), tablets (200 mg).
• Acetylcysteine ​​TEVA. Effervescent tablets of 200 and 600 mg.

The selection of analogues with another active substance should be handled by a doctor. Not in every case, replacement with another mucolytic is equivalent.

Preference is given to preparations based on ambroxol. Showed the effectiveness of the cheap syrup of the same name and a little more expensive analogues(Lazolvan, Ambrohexal). According to the annotations, the pediatrician has the right to prescribe them to children under 2 years old.

Carbocysteine ​​is considered as an alternative. The cost of medicines based on it (for example, Fluditec) is somewhat higher.

drug interaction

Do not take with cough suppressants. Inhibition of the reflex contraction of the bronchi leads to stagnation of sputum.

Should not be used in conjunction with oral antibiotics. Interaction leads to a decrease in their effectiveness. The difference between the time of entry into the body should be at least 2 hours (exceptions include cefixime and loracarbef).

With nitrates, as well as other substances with a vasodilatory effect, an increase in the vasodilating effect is possible. This can lead to a marked decrease in blood pressure.

Although the vial is tamper-evident, it should be kept out of the reach of children. The optimum storage temperature is up to 25 °C inclusive.

Before opening the package, it is suitable for consumption within 2 years. After the first violation of tightness, it is stored no more than 10 days. Is in pharmacy sales without recipe.

ACC is firmly entrenched in pediatric practice due to its effectiveness and safety. It is officially included in the list of vital and essential medicines.

Before taking, you should consult with your doctor. If you drink the medicine "blindly", you can reduce the symptoms dangerous disease and skip its progression. This is especially worth remembering when a child is sick.

Unfortunately, my daughter got sick in the summer. And we had a trip to the lake. Naturally, my husband and I would have stayed at home to treat her, however, since we all wanted to rest, we set about intensive treatment. I asked the doctor for powerful drugs that would harmlessly cure our girl in a short time. We were prescribed a treatment complex, which included ACC syrup. This is a drug specifically for children. It's hard to believe, but we recovered in 4 days. On the 5th day from that moment the trip took place. Alla, 30 years old

Our son gets sick almost every autumn. Only this time I completely forgot to stock up on medicines, so I had to run to the pharmacy and take what was already in stock. The pharmacist recommended this product to us. I looked at the instructions on the spot, checked everything and bought a miracle syrup. Unfortunately, it turned out to be not tasty and ended quickly, but at least the price was normal. We did not fully recover, we were still cured by folk methods. Irina, 44 years old

The tool is inexpensive. It is an analogue of another more expensive drug. So in the therapeutic effect, it seems that this medicine justified its cost. Although the reviews are mostly good. Usually he drinks syrups with pleasure, but for some reason he refused this mixture, he had to force it. And the effect didn't last long. We had to take 30 ml per day, i.e. three times 10 ml. And the bottle contains 100 ml of a viscous liquid. On the 4th day, I had to go to the pharmacy for a new remedy, only for another. We did not like this syrup. Love, 31 years old

I really love this syrup. It's nice, efficient, and inexpensive. The baby and I are used to it. No allergies, no disgust, nothing so bad, the drug does not cause. At least we have. When we have problems with sputum discharge, this drug comes to the rescue and always copes with its task with a bang. The child was given three times a day, one measuring cap after meals. The last time was treated for a week, everything is fine. It happens that we get better in three days. Valentina, 29 years old

Unfortunately, after opening, you can store no more than 18 days. Of course, basically, it ends in a week. Its 100 ml is barely enough for a few days. However, it happens that everything passes in a couple of days, and then it’s a pity to throw away an almost full bottle. For me, this is a minus. The rest seems to be good. I saw the effect when my child began to wheeze less already on the second day of taking the syrup. The price is acceptable. The taste is pleasant, the consistency is good, etc. Manufacturers should solve the problem with the form of release and its shelf life. Tatyana, 34 years old

Cough - common symptom many diseases in children, including common cold, bronchitis, tracheitis, pneumonia and so on. Modern drugs from a cough will help to cope with it, remove sputum and speed up the healing process. To one of these modern drugs that can be used in pediatric age category, include a drug called ACC. This mucolytic is available in convenient forms for children of different ages: effervescent tablets, granules for making syrup, in powder.

Pharmacological effect drug ACC based on the action of acetylcysteine, which is part of the agent, which effectively affects the viscous accumulated sputum, changing its properties and removing it from the respiratory tract of the child, and also has an anti-inflammatory effect directly in the focus of inflammation.

Indications for use of ACC

Indications for the appointment of ACC are pathological conditions accompanied by a dry cough or with sputum. These conditions include: tracheitis, laryngitis, acute period and in chronic forms, acute bronchitis or exacerbation chronic form bronchitis, pneumonia (acute inflammation of the lung tissue), asthma, lung abscess, bronchiectasis and cystic fibrosis.

In addition, ACC is used for acute inflammation of the paranasal sinuses and inflammation of the inner ear, since mucus is also formed in these pathologies. upper divisions respiratory tract. ACC is quite effective and is used in children with dry cough.

At what age can children be given the drug?

ACC is allowed to be used with infancy, after 10 days of life in the form of a syrup, which is pre-prepared from granules in a dosage corresponding to age, if ACC at that age was prescribed by a pediatrician. Children 2 years of age and older may use ACC medicines in the form of effervescent tablets.

How to properly breed and take ACC for a child

Syrup granules

In infants and children under two years of age, the drug is taken as a syrup on the recommendation of a pediatrician, half a measuring spoon three times a day.

The syrup is made from granules by adding room temperature water to a special mark that can be found on the bottle.

Powder for hot solution

In order to prepare a hot drink, you need to ACC powder add hot water at the rate of one sachet per glass of water, then the solution is mixed and taken hot after eating.

This solution can be stored for 3 hours. But it is advisable to drink it immediately after preparation.

How to give effervescent tablets

A child already over the age of two years, but under six years of age, is recommended to take ACC in the form of effervescent tablets at an age dosage of 100 mg three times a day or two effervescent tablets at the same dosage, but already twice a day.

Effervescent tablets must be dipped in about half a glass of water, they dissolve, and the already obtained solution is used after eating and completely dissolving these tablets. Prepared this way ACC solution can be consumed for about two hours, but it is advisable to drink it immediately after preparation.

For children over six years of age, the dosage is two pops or two sachets of ACC with granules up to three times a day. These granules can be dissolved not only in ordinary water, but also in tea or juice.

Contraindications and side effects

ACC is generally well tolerated by children. However, they may appear unwanted effects. Of the side effects, an allergic reaction is noted in the form of urticaria, an itchy rash or Quincke's edema, fever, low blood pressure, increased heart rate, ringing, pain in the head can be heard in the ears. Quite rarely, but the appearance of dyspnea, bronchospasm is possible, especially in patients with a history of bronchial asthma. On the part of the digestive tract, a feeling of nausea, vomiting, heartburn, loose stools, the appearance of nonspecific pain in the abdomen, manifestations of stomatitis - inflammation of the oral cavity are possible. It is possible to develop bleeding while taking ACC, which is associated with a hypersensitivity reaction. Skin side effects in the form of Lyell's syndrome have been reported. The development of cases of anaphylactic shock has been rarely reported.

If any side effects, reactions, or changes in the mucous membranes or skin appear while taking ACC, you should immediately consult a doctor.

When using an excess dose of the drug, vomiting, nausea, abdominal pain, and loose stools may occur. It is necessary to inform the doctor immediately if such symptoms appear.

Drug analogues

Similar ACCs will be such cough remedies as acestin, acetylcysteine, Vix Active ExpectoMed, mukobene, mukomist, mukonex, fluimucil. In all these preparations, the main substance, as well as in ACC, is acetylcysteine.

This drug helps to fight cough with viscous sputum, which is difficult to liquefy and excreted.

The drug is prescribed to combat chronic bronchitis, patients with cystic fibrosis, as well as otitis media or sinusitis. Helps ACC and heavy smokers with lung changes. For some diseases, long-term use is expected. If we treat an acute process, it is usually prescribed for 7 days.

All ailments from which ACC is attributed are associated with acute process or vice versa with a chronic cough. And if you have a cough, you need to see a doctor. And ACC should only be taken with a doctor's prescription., he also determines the appropriateness of the appointment and how long to take, and if necessary, prolong the medication. Or you may not be prescribed it at all, because you have a different kind of cough.

All parameters show that such a drug should not be prescribed to oneself. In the case of cough, you can try herbal treatment, but observation does not exclude this.

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