Viferon candles 1 instructions for use. Candles for children Viferon: instructions for use, composition, indications and analogues

Children often suffer from colds and acute viral infections, especially in the first years of life. This is because their immune system has not yet developed, making them vulnerable to viral and bacterial attacks. Pathogenic microbes enter the body, actively multiply, and worsen the child’s condition. In such cases, complex treatment using immunomodulators is necessary.

Viferon is a drug with a pronounced antiviral and antibacterial effect. The medication stimulates the body's defenses, speeds up recovery and prevents complications. Can Viferon be used by a child for the treatment and prevention of diseases of viral and bacterial origin? More on this later.

Description of dosage forms

Most suitable for children pharmaceutical form– these are rectal suppositories 150,000 IU. For adults, the drug is produced with a concentration active component 500,000 and 1,000,000 IU. These are torpedo-shaped candles, white or yellowish in color. Suppositories with a diameter of about 1 cm and a soft consistency are easily inserted into anus.

  • interferon α-2b;
  • α-tocopherol acetate;
  • vitamin C;
  • sodium salt of ascorbic acid;
  • Twin 80;
  • disodium salt of ethylenediaminetetraacetic acid;
  • cocoa butter;
  • cooking fat.

In addition, the drug is produced in the form of ointment and gel, which have the following composition:

Viferon ointment:

  • interferon α-2;
  • tocopherol acetate;
  • anhydrous form of lanolin;
  • petrolatum;
  • peach oil;
  • distilled water.

  • interferon α-2b;
  • α-tocopherol acetate;
  • methionine;
  • additive E210;
  • food additive E330;
  • technical drill;
  • sodium chloride;
  • human albumin solution (10%);
  • glycerol;
  • carmellose sodium;
  • ethyl alcohol (95%);
  • distilled water.

The drug in gel form looks like a homogeneous mass of gray-white hue, and the ointment is a homogeneous substance with the aroma of lanolin.

Properties of Viferon

Interferon α-2b (main component) is synthetic analogue human interferon natural origin. These proteins respond to the invasion of harmful microorganisms.

The protein compound has the following properties:

  • Interferon binds to receptors on the membrane of the virus and inhibits its reproduction inside the infected cell.
  • The substance stimulates functional activity immune system. In addition, interferon improves the functioning of cellular and humoral immunity. The protein compound enhances the production of secretory IgA (immunoglobulin A) and normalizes the concentration of immunoglobulin E, which detects diseases of an allergic nature.
  • Interferon has an antiproliferative effect. The substance inhibits excessive cell proliferation at the site of infection. In addition, Viferon suppositories have an antitumor effect.
  • Interferon stimulates phagocytic activity. As a result, macrophages (immune cells) absorb pathogens more quickly.
  • The substance stimulates the cytotoxic activity of white blood cells(leukocytes) in relation to infected cells.

Ascorbic acid enhances medicinal properties interferon. In addition, it inhibits the oxidation of organic compounds, stabilizes cell membranes, and promotes the restoration of damaged tissues.

Suppositories take effect 15 minutes after use. The components penetrate the bloodstream, stimulate the immune system, and eliminate inflammation.

Indications

As the instructions say, Viferon suppositories are used to treat diseases of viral and bacterial origin:

  • Respiratory diseases viral nature, including influenza severe form or complicated infection of bacterial origin due to decreased immunity.
  • Infectious and inflammatory diseases (inflammation of the mucous membranes of the brain and spinal cord viral or bacterial origin, bacterial sepsis). Intrauterine diseases caused by cytomegaloviruses, enteroviruses, chlamydia, ureaplasma and herpes viruses. The medication is used as part of complex treatment.
  • Hepatitis B, C, D, E of viral origin with chronic course. The drug is taken in combination.
  • Infections genitourinary organs V chronic form. Chlamydial infection, ureaplasmosis, bacterial vaginosis, thrush, etc.
  • Herpes on the skin or internal membranes with a chronic recurrent or severe course.

In addition, suppositories improve the functional activity of the immune system during chronic diseases of bacterial origin.

Directions for use and dosage

As already mentioned, Viferon suppositories for children are used rectally, that is, they are inserted into the rectum. Before using the drug to treat a child, you need to familiarize yourself with the technology for administering a suppository:

  1. Wash your hands with antibacterial soap.
  2. Remove the suppository with interferon concentration 150,000 from the blister.
  3. Turn the child on his side or lay him on his back, bend his knees.
  4. Gently insert the suppository with the pointed tip into the anus. The permissible insertion depth is 2 cm. Press with your little finger on the blunt side of the candle. Before insertion, you can treat the perianal area (the area around the anus) with Vaseline or baby cream. However, this point can be skipped, since the candle already contains fatty substances, which heat up upon contact with the skin, and therefore do not cause discomfort.
  5. Squeeze your buttocks for a couple of minutes to prevent the suppository from slipping out.

Daily dosage of the drug for children of different ages:

  • from 0 to 12 months - 1 suppository twice with an interval of 12 hours. If the baby is premature, the interval between administrations is 8 hours. The therapeutic course lasts 5 days; if necessary, the pediatrician will extend the treatment. At viral hepatitis Children under 6 months are administered about 500,000 IU of interferon per 24 hours.
  • from 1 to 7 years – 1 suppository twice, treatment lasts 5 days.
  • from 8 to 12 years, suppositories with an interferon concentration of 500,000 IU are used. The daily dose is 1 suppository twice for 5 days.

Before using the drug, you need to visit a pediatrician who will establish a diagnosis, determine the dose, frequency and duration of use of Viferon.

Viferon for the prevention of infections of viral origin guarantees excellent result. The dose of the drug is determined by the doctor depending on the age of the patient.

special instructions

Patients tolerate suppositories well; they should not be used only in case of hypersensitivity to the components of the drug.

If there are contraindications, adverse reactions in the form of allergies:

  • rash;
  • nettle fever.

There is no information about severe allergic reactions such as angioedema or anaphylaxis.

Before using the medicine, it is recommended to carefully study the instructions. There are several points that require special attention:

  • Components of the drug when joint use do not enter into chemical reactions with medications of other pharmacological groups.
  • At simultaneous use Viferon and antibacterial drugs for the treatment of infections of bacterial origin first enhances therapeutic effect others.
  • If an allergy occurs, you should stop taking the drug. After that negative reactions will disappear 3 days after cancellation.
  • Suppositories are allowed for use by newborns. In addition, the drug in this form is compatible with pregnancy and lactation. However, the doctor must monitor the condition of a special group of patients.
  • The medication does not affect the patient’s memory and attention, and does not interfere with psychomotor reactions.

The drug is available without a prescription.

Similar drugs

If there is hypersensitivity to the components of the drug, Viferon can be replaced with drugs with a similar active substance and mechanism of action:

  • Laferobion based on interferon α-2b is also produced in the form of rectal suppositories. The drug is used to treat respiratory diseases of viral origin and influenza. The medication stimulates the immune system and eliminates pathogens.
  • Alfarequin contains a similar active ingredient. Rectal suppositories are used to treat infections of viral and bacterial origin. The medicine is intended for newborns from 3 months.
  • Alfaron is manufactured in the form of a lyophilisate for the preparation of an intranasal solution. The medication is prescribed for the treatment of influenza in children from birth.

Thus, Viferon is a universal complex drug for the prevention and treatment of viral and bacterial infections. The medicine causes side effects only if you are allergic to its components. Before using the medicine to treat children, you should consult your pediatrician.

This drug is effective for viral infections. It is prescribed to children, adults, and pregnant women. To prevent negative consequences from taking Viferon, it is better to study the instructions before starting treatment.

In pharmacies you can find ointment, gel and rectal suppositories Viferon. Perhaps you have not used preparations in the form of suppositories before, especially rectal ones; suppositories have this name due to the fact that their area of ​​application is the rectum (from the Latin rectum). It is where the drug is absorbed from the mucosa and then enters the blood.

Viferon suppositories mainly consist of an active component - human recombinant interferon alpha-2, this is the name of a synthetic protein that is obtained in the laboratory by geneticists. He's exactly the same as human interferon produced by an organism that is immune reaction for a bacterial or viral infection. The instructions for use of Viferon suppositories state that the effect of the drug is based on the joint work of artificial interferon together with natural interferon and the activation of the production of the latter.

Interferon alpha-2 has the greatest antiviral effectiveness, it differs from similar immunomodulatory drugs in its good effectiveness against influenza, herpes, hepatitis and similar diseases. Diseases that appear due to the presence of atypical bacteria or protozoa respond well to treatment with interferon; ureaplasmosis, chlamydia, gardnerellosis, and trichomoniasis are successfully treated with drugs containing this protein.

The use of interferon is also effective against infections caused by fungi, such as candidiasis and mycoplasmosis. As you know, Arbidol, Kagocel, Anaferon also contain interferon, in particular, many effective medicines have been created on its basis.

It is worth noting that Viferon contains substances that enhance its effectiveness and eliminate possible side effects. For example, the ointment contains vitamin E, and the composition of the gel, in addition to tocopherol acetate, is represented by benzoin and citric acid, a methionine solution containing alcohol and a substance that has no less effective immunomodulatory properties than interferon - human serum albumin.

note

The candles are highly effective and have a strong antioxidant effect thanks to vitamin E and ascorbic acid. Also, any dosage form, regardless of whether it is a suppository or an ointment, contains additional components, full composition which are described in detail in the instructions for the drug.

It should be noted that before starting treatment, you should learn in detail about the composition of the drug (this applies not only to Viferon), especially if you have an allergy, because if you are intolerant to any component contained in the suppositories, you cannot use this form of the drug.

Do not use suppositories if the body has shown individual sensitivity to the substances contained in the drug. In particular, such a reaction can occur with ascorbic acid and alpha-tocoverol acetate. During pregnancy, no earlier than 14 weeks, Viferon suppositories are allowed to be used. The instructions for use do not contain information about contraindications of the drug during breastfeeding.

This drug is distinguished by its safety, thanks to which its use is allowed even for newborns. During treatment, adverse reactions may develop, such as, however, after stopping use for three days, the rash will disappear. If any reactions occur after starting treatment, a mandatory consultation with a doctor is necessary. In any case, it should be noted that such adverse reactions are not life-threatening, stop within 3 days and do not require additional therapy.

Viferon suppositories for adults: in what cases are they prescribed?

This drug is also called human recombinant interferon, which is its international name. He is rectal suppositories yellowish color having a diameter of no more than 1 cm. Produced with an interferon content identical to that produced by the human body.

Its action is based on working together with natural interferon, as well as stimulating its production. Ascorbic acid and vitamin E, also included in the drug, activate immunomodulatory and antiviral effect Thus, the body's immune response to bacterial infection is stimulated. Ascorbic acid and alpha-tocopherol acetate also have high antioxidant, anti-inflammatory and regenerating effects . Viferon suppositories for adults stop development inflammatory processes , also cell membranes resume their full function. With these substances, interferon acts more effectively, prompting the body to fight on its own.

note

When treatment with Viferon occurs in conjunction with antibacterial therapy, the latter can be prescribed in a smaller dose, which reduces Negative consequences treatment on the human body. When Viferon is used for a long time, the formation of antibodies that neutralize its effect is not observed.

In what cases is Viferon prescribed? This drug can be used regardless of age; treatment with Viferon is prescribed even to newborns and premature babies.

It is effective for children with the following diseases:

  • ARVI, colds with or without bacterial complications;
  • pneumonia of various etymologies;
  • infectious diseases in newborns;
  • viral hepatitis;
  • as preventative measure from acute respiratory viral infections, acute respiratory infections, influenza for children prone to frequent illnesses;
  • as a fortification protective forces when the body is weakened by an infection.

The instructions describe in detail the use of the drug, the dosage and duration of treatment are prescribed by the attending physician. Viferon suppositories are produced with different amounts of interferon, so you can choose them for a child of any age with the right dosage in 1 candle, this also eliminates excess required dose, you just need to carefully choose the drug when purchasing in order to strictly follow the doctor’s prescription.

It is advisable to maintain equal intervals between the use of candles. For the treatment of influenza, ARVI, acute respiratory infections, it is recommended to use 1 suppository rectally twice a day for a five-day course of treatment. In other cases, treatment can last longer - 10-60 days, depending on the course of the disease. Also, the effect of treatment is influenced by compliance with the rules for using the drug, in particular in newborns.

Technology for introducing suppositories:

  • The procedure is carried out wearing sterile gloves or cleanly washed (disinfected) hands.
  • For the baby lying on his stomach or side, insert the suppository deeply into the anal area.
  • Continue to lie without changing position for at least 10 minutes until the drug is completely dissolved.
  • For older children, suppositories should be administered after bowel movements.

Pregnancy. Adult dosage Viferon 4 is not used for pregnant women when gynecological and other diseases occur, expectant mother a small dosage of the drug is required, usually for adolescents (1,000,000 IU) or children's (50,000 IU). But even in this case, there are certain restrictions for pregnant women; Viferon is prescribed no earlier than 14 weeks and only during breastfeeding suppositories are prescribed without any fear. In principle, even during pregnancy planning, it would be more correct to treat all diseases, treatment will be more effective, because when choosing required drug there will be no restrictions.

Viferon suppositories used in the rectum only provide general action, Unlike vaginal preparation Genferon, which carries out treatment locally. Of course, it is useless for viral infections, but urogenital diseases are better treated with Genferon.

It relieves pain due to the fact that it contains benzocaine and the amino acid taurine, in particular, the use of benzocaine is contraindicated during pregnancy. Drugs containing it can be prescribed exclusively in the second half of the term, and then the expected benefit must exceed possible harm for the baby.

note

It is very important to strictly follow the doctor’s prescription and not change it yourself without prior consultation, especially since Genferon and Viferon are not equally safe for pregnant women. Only the attending physician knows which drug you need.

As is known, even drugs administered rectally enter the bloodstream, but side effects Viferon suppositories are not as extensive as those of subcutaneous, intramuscular and intravenous drugs containing interferon. If this mechanism is not clear to you, you can search Additional information about the absorption of substances by the intestines, however, it becomes obvious that the use of Viferon in the form of rectal suppositories is much less likely to have negative consequences, even less local ointments and gels.

To be fair, it should be noted that treatment with Viferon, like any drug, may not be possible without side effects. By the way, Russian manufacturers the list of possible consequences is indicated in great detail in the attached instructions, so you should read it carefully before starting treatment.

Rectal suppositories Viferon and their use for the treatment of children

Most often, mothers of newborns and pregnant women are looking for additional information about taking the drug, there is nothing strange in this: Viferon rectal suppositories are usually prescribed for the treatment of infants from respiratory and herpetic infections, atypical pneumonia and similar diseases posing a direct threat to the life of a newborn baby.

Viferon is often prescribed by gynecologists- it successfully cures vaginal infections fungal, bacterial or viral in nature, and infectious diseases, such as: flu, acute respiratory infections and others. The prescription of this drug by gynecologists, neonatologists and pediatricians in itself serves as a convincing argument that it has low toxicity, in addition, there are no serious side effects from its use.

The action of the suppositories occurs locally, the components of the drug are absorbed in the rectum and then enter the blood. Therefore, it is necessary that the interferon contained in the drug be in the exact dosage.

Manufacturers took care of this by releasing Viferon in the form of candles with different dosage active substance:

  • Infants and children under one year of age are prescribed Viferon 1 (contains 150 thousand IU).
  • At the age of 1-7 years, Viferon 2 (500 thousand IU) is used.
  • For children 7-12 years old, the dosage of Viferon 3 is suitable.
  • For teenagers and adults Viferon 4 (3 million IU).

It is imperative to strictly follow the dosage prescribed by the doctor, and also use the drug as indicated in the instructions for it in strict accordance with age. It is strictly forbidden to use a large dosage of suppositories to treat a newborn, but a low dosage for older children will also be ineffective. As a rule, all negative reviews about the low effectiveness of the drug are associated with the use of a dose that is not appropriate for the child’s age.

Viferon suppositories for prostatitis, features of their use for treatment

The prostate is the second heart of a man, men are especially sensitive to the state of its health, but from time to time problems occur with this gland, and therefore the treatment of inflammatory diseases of this important body should be taken extremely seriously.

For a long time in a complex drug therapy prostatitis, rectal suppositories Viferon are used, which fight viruses and encourage the immune system to more active work. Antiviral effect is ensured due to the fact that interferon destroys RNA and DNA, which are the basis of life and replication of viruses that invade and damage cells.

Stimulation of the immune system occurs because interferon activates T and B lymphocytes and increases the phagocytic activity of cells immune defense- macrophages. Also, Viferon suppositories for prostatitis normalize the level of immunoglobulin E, and consequently, the body’s overall immune response against pathogenic microorganisms increases.

Viferon rectal suppositories contain vitamins E and C, known as antioxidants, due to this the anti-inflammatory effect of the drug is significantly enhanced, and it also protects the lipid layer cell membranes from peroxidation.

The drug enhances the ability of tissues to regenerate, this confirms the validity of prescribing Viferon suppositories for various forms inflammatory diseases of the prostate gland. Viferon suppositories for prostatitis work well in combination with other medications, especially antibiotics wide range actions, and therefore can be used in complex treatment prostatitis.

1-2 suppositories are administered per day with an interval of 12 hours. The course of treatment is 5 days.

IN pharmacy chain There are preparations similar to these suppositories, they are identical in composition, pharmacological action and therapeutic effect.

Sometimes the difference is only a different commercial name, for example:

  • Laferobion.
  • Laferon.
  • Interferon.
  • Genferon.
  • Lipoferon.

The price of rectal suppositories Viferon is quite high due to its uniqueness technological process during its production, but when it comes to health, especially the health of such an important organ as the prostate, then price is the last thing to think about.

I would like to warn patients against the danger of buying a drug that is 2 times cheaper than the current price. There is a high probability of purchasing a counterfeit, and this will not help your recovery and can cause harm.

Suppositories rectal Viferon sold in pharmacies without a doctor's prescription. However, despite the safety of use, it is recommended to consult a doctor, specialist, after full examination, establish the correct diagnosis and timely prescribe individual treatment.

Most men of different age groups noted a decrease pain syndrome, improvement in urination on days 2-4 from the start of using suppositories.

According to reviews of mothers who used suppositories for treatment colds in children, more than mild course diseases, faster recovery and absence of complications of the disease; the earlier treatment was started, the better the result.

In conclusion, it should be noted that in addition to its use in the treatment of prostatitis, Viferon is widely used in pediatric and general therapeutic practice. Candles can also be used in complex therapy severe infections, sepsis, meningitis, fungal infections, chlamydia, mycoplasmosis, all forms of chronic viral hepatitis.

"Viferon" refers to antiviral drugs, a relatively new series of drugs. Instructions for using Viferon suppositories for children contain little information about long-term consequences his reception. This is due to the fact that medicine does not yet have enough data to evaluate. However, it is important for parents to understand how harmless the drug is, which is prescribed even to babies under one year old.

The main problem with viral infections is that there are antibiotics against bacteria, but nothing has been developed against viruses. If bacteria, protozoa and even fungi are individual microorganisms, then a virus is a fragment foreign DNA, which:

  • “adds” itself to the DNA of its own body cells;
  • due to this, it becomes unrecognizable to immune cells;
  • “hides” behind a cell membrane that is impenetrable to them.

Until now, all these features have made viruses virtually invulnerable to immune defenses and drugs. It is assumed that the appearance antiviral drugs reversed this trend. But there is no reliable data yet on whether this is actually the case.

How does the medicine work?

"Viferon" is a drug that contains recombinant (synthesized by methods genetic engineering) immune agents interferons. It is released in the form:

  • gel;
  • ointments;
  • rectal suppositories.

Interferons are proteins synthesized by a cell in response to a virus infecting the body. Their molecules are located on the surface of cell membranes and “catch” viruses trying to penetrate them.

These proteins come in several types (depending on which cells secrete them), and serve as a mechanism of cellular self-defense against invading foreign DNA. With normally functioning immunity, in the first few days after infection the number of interferons on the surface of cells increases sharply, remains high for another one to two weeks, gradually decreasing to normal.

Preparations containing interferons presumably provide the same effect. This allows:

  • quickly increase cell resistance to viral infection;
  • increase it even if your own immunity fails;
  • ensure prevention by starting to take the drug before the suspected infection.

Why caution is needed

The principles of the immune system, like the brain, have been studied by science only 10-15%. Hence the impossibility of predicting how he will respond to “assistance” with interferons in difficult cases. For example, if the patient suffers from immunodeficiency, allergies, or other immune disorders. In addition, the long-term side effects of the drug itself are not entirely clear; they have not yet been observed.

There is also a purely medical opinion that suppositories, tablets and ointments/gels/creams based on interferons are placebos. Not a single whole protein molecule can penetrate the skin or intestinal walls into the blood. The skin will not let it in under any circumstances, and when digested (if you take it in tablets), it will break down into amino acids, losing its special structure and purpose. It turns out that it makes sense to take interferons only in the form of injections...

When is it prescribed?

As always, when a new drug appears, parents have a question about why Viferon suppositories are prescribed to children. It is now clear that Viferon candles are needed for a child as antiviral agent, and indications for their use are viral (not bacterial or fungal) infections, as well as diseases that cause immunodeficiency:

  • ARVI;
  • flu;
  • viral hepatitis;
  • HIV and AIDS;
  • exacerbation of herpes;
  • diabetes;
  • pneumonia;
  • rotavirus infection;
  • chickenpox.

It is also believed that Viferon can be prescribed for chlamydia and trichomoniasis (both infections are caused by protozoa), recurrent candidiasis (fungal infection). It is often prescribed for sore throat, runny nose and other manifestations of acute respiratory infections.

The constant expansion of the circle of his appointments is facilitated by the fame that has attached to him effective means to reduce temperature. In addition, parents (and doctors too) are encouraged to do this by how quickly Viferon suppositories act. Really, high temperature they take off, on average, within the next half hour, and this effect lasts about a day. And other symptoms of the pathology subside within an hour or two. However, reviews from doctors about the results of using Viferon antipyretic suppositories for infant quite reserved.

Possible risks

The instructions for using Viferon suppositories for children indicate only one contraindication - that they should not be used if there is an individual intolerance to any components in their composition.

Among the side effects of Viferon for an infant, only temporary allergic reactions, mainly in the form of urticaria, are described. And cases of overdose, according to official information, have not yet been identified. Such a limited list negative effects may equally likely be due to:

  • the drug has not yet been studied well;
  • it really does not penetrate the body in this form;
  • it's safe.

However, Viferon, like any other product developed less than ten years ago, should not be considered safe just because the instructions for it do not indicate the opposite. Therefore, it should not be used to treat mild infections, as well as completely “non-core” cases - for example, fever during teething.

Instructions for use and analogues of "Viferon" for children

Viferon rectal suppositories may contain different numbers of interferon molecules. Their minimum content in one suppository is 1,000,000 IU, the maximum is 500,000 IU. The only question is how to administer Viferon suppositories to a baby, especially an infant. The dosage of Viferon suppositories for small children is different in each case.

For viral and mixed pathologies of the upper respiratory tract

The appointments are:

  • children under seven years of age and slightly premature - one suppository of 150,000 IU every 12 hours for five days;
  • children over seven years old -“adult” suppositories with a dosage of interferon 500,000 IU, according to the same scheme;
  • very premature babies - antiviral suppositories"Viferon" for children under one year of age is administered one dose (150,000 IU) every eight hours for five days in a row.

This is followed by a five-day break, and if the symptoms of the disease persist, the course can be repeated.

For systemic and generalized infections (including intrauterine)

The drug is used in the following doses:

  • meningitis - involves two courses of treatment for five days at a dosage of 150,000/500,000 IU every 8-12 hours (depending on the age of the child);
  • herpes - requires the appointment of two or three such courses;
  • fungal infections - two or three courses in combination with antifungal drugs.

The schedule of their treatment with Viferon in various age groups completely identical to that specified in the previous paragraph. But given the scale and complexity of the process, such infections almost always require a repeat course.

For viral hepatitis

They are treated with Viferon at any age for at least six months. In this case, the drug is administered every 12 hours. During the first ten days this is done daily, then every other day, in the dosage:

  • children under six months of age - 300,000 IU per day;
  • children aged six months to one year – 500,000 IU per day;
  • children aged from one to seven years – at the rate of 3,000,000 IU of active substance per m2 of body area per day;
  • children aged seven years and older – at the rate of 5,000,000 IU of active substance per m2 of body area per day.

Analogs

Currently, there are already enough interferon-based drugs in Russia, and their range is constantly being updated with new modifications. Among the analogues that are closest in composition and method of use:

  • "Alfarekin" - suppositories made in Ukraine;
  • "Vitaferon" - suppositories made in Ukraine;
  • "Laferobion" - suppositories made in Ukraine;
  • "Laferon" - suppositories made in Ukraine;
  • “Viferon-Feron” – suppositories produced in the Russian Federation;
  • "Genferon" - suppositories produced in the Russian Federation.

At the same time, you should not expect a significant difference in price from analogues of Viferon candles for a child compared to the original.

Print

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If you have questions about the use of Viferon suppositories during pregnancy, see the article.
If you do not understand how to properly administer Viferon rectal suppositories, see the article.
Viferon price: in Moscow, Ukraine, Belarus.
ABOUT correct selection For dosages of Viferon suppositories in questions and answers, read the article

Information on how to properly store Viferon candles in the form of questions and answers can be found in the article

Trade name of the drug

Viferon®

Manufacturer

Feron LLC, Russia

International nonproprietary name

Interferon human recombinant alpha-2

Dosage form

Rectal suppositories

Release form

Suppositories (150,000 IU, 500,000 IU, 1000,000 IU, 3,000,000 IU) weighing from 0.95 g to 1.05 g, 10 pieces each in PVC/paper strip packaging or weighing from 1.00 g to 1.10 g, 10 pieces in PVC/PVC blister packaging. 1 or 2 blister packs with instructions for use in a cardboard pack

Description

The suppository is bullet-shaped, yellowish-white in color, and has a uniform consistency. Inhomogeneity of color in the form of marbling and the presence of a funnel-shaped depression on the cut are allowed. The diameter of the suppository is no more than 10 mm.

Pharmacotherapeutic group

Immunomodulatory and antiviral agent.

Active substance

1 suppository VIFERON 150,000 IU contains the active substance - human recombinant interferon alpha-2 150,000 IU;
1 suppository VIFERON 500,000 IU contains the active substance - human recombinant interferon alpha-2 500,000 IU
1 suppository VIFERON 1000000 IU contains the active substance - human recombinant interferon alpha-2 1000000 IU
1 suppository VIFERON 3,000,000 IU contains the active substance - human recombinant interferon alpha-2 3,000,000 IU

Excipients

Ascorbic acid 0.015 g, alpha tocopherol acetate 0.055 g, base cocoa butter or solid fat

pharmachologic effect

Human recombinant interferon alpha-2 has pronounced antiviral, immunomodulatory and antiproliferative properties. The complex composition of the drug determines the presence of a number additional effects: in the presence of ascorbic acid and alpha-tocopherol acetate, the antiviral activity of human recombinant alpha-2 interferon increases, its immunomodulatory effect on T- and B-lymphocytes is enhanced, the level of immunoglobulin E is normalized, and the functioning of the endogenous interferon system is restored. In addition, ascorbic acid and alpha-tocopherol acetate, being highly active antioxidants, have anti-inflammatory, membrane stabilizing, and regenerating properties. It has been established that when using VIFERON there are no side effects that occur when parenteral administration interferon preparations, and antibodies that neutralize the antiviral activity of interferon are not formed.

Pharmacokinetics

After rectal administration after 12 hours, a decrease in serum concentration is observed, which necessitates its repeated administration.

Indications for use

In the complex therapy of various infectious and inflammatory diseases in children, including newborns and premature infants:

  • acute respiratory viral infections(flu, ARVI, including complicated bacterial infection),
  • pneumonia (bacterial, viral, chlamydial),
  • meningitis (bacterial, viral),
  • sepsis,
  • intrauterine infection (chlamydia, herpes, cytomegaly, enterovirus infection, candidiasis, including visceral, mycoplasmosis);
In complex therapy chronic viral hepatitis B, C, D in children and adults, including in combination with the use of plasmapheresis and hemosorption,
for chronic viral hepatitis of pronounced activity and complicated by cirrhosis of the liver;
in complex therapy in adults, including pregnant women, with urogenital infection(chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, human papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis),
primary or recurrent herpetic infection skin and mucous membranes, localized form, lung and moderate course, including the urogenital form;
in complex therapy, including those complicated by bacterial infection in adults.

Dosage regimen

Suppositories containing human recombinant alpha-2 interferon as an active substance in the indicated dosages (150,000 IU, 500,000 IU, 1,000,000 IU, 3,000,000 IU) are used rectally.
In the complex therapy of various infectious and inflammatory diseases in newborns, including premature: newborns, including premature infants with gestational age more than 34 weeks VIFERON is prescribed 150,000 IU* daily, 1 suppository 2 times a day every 12 hours. The course of treatment is 5 days.
Premature newborns with gestational age less than 34 weeks VIFERON is prescribed 150,000 IU daily, 1 suppository 3 times a day after 8 hours. The course of treatment is 5 days.
Recommended number of courses for various infectious diseases - inflammatory diseases at children, including newborns and premature babies:

  • influenza, ARVI, including those complicated by bacterial infection - 1-2 courses;
  • pneumonia(bacterial, viral, chlamydial) – 1-2 courses,
  • sepsis– 2-3 courses,
  • meningitis– 1-2 courses,
  • herpetic infection– 2 courses,
  • enterovirus infection– 1-2 courses,
  • cytomegalovirus infection – 2-3 courses,
  • mycoplasmosis, candidiasis, including visceral, – 2-3 courses.
The break between courses is 5 days. By clinical indications therapy can be continued.

In complex therapy chronic viral hepatitis B, C, D in children and adults: for children with chronic viral hepatitis, the drug is prescribed in the following age-specific dosages: up to 6 months 300,000-500,000 IU per day; from 6 to 12 months– 500,000 IU per day. Aged from 1 year to 7 years– 3,000,000 IU per 1 m2 of body surface area per day. Aged over 7 years old– 5,000,000 IU per 1 m2 of body surface area per day. for each specific patient is produced by multiplying the recommended of this age dosage per body surface area calculated according to nomogram to calculate body surface area by height and weight according to Garford, Terry and Rourke, divide into 2 administrations, round up to the dosage of the corresponding suppository. The drug is used 2 times a day every 12 hours for the first 10 days daily, further three times a week every other day for 6-12 months.
The duration of treatment is determined clinical effectiveness And laboratory indicators. Children with chronic viral hepatitis of severe activity and liver cirrhosis before the plasmapheresis and/or hemosorption the use of the drug is indicated for 14 days daily, 1 suppository 2 times a day every 12 hours(for children under 7 years old VIFERON 150,000 IU, for children over 7 years old - VIFERON 500,000 IU).
Adults with chronic viral hepatitis VIFERON 3,000,000 IU is prescribed, 1 suppository 2 times a day every 12 hours for 10 days daily, then three times a week every other day for 6-12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.
In complex therapy adults, including pregnant women, With urogenital infection(chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis), with primary or recurrent herpetic infection skin and mucous membranes (localized form, mild and moderate course, including the urogenital form).
For adults, with the above infections, except herpes, Viferon is prescribed 500000 IU By 1 suppository 2 times a day every 12 hours. Course 5-10 days. According to clinical indications, therapy can be continued with breaks between courses of 5 days.
At herpetic infection VIFERON is prescribed 1000000 IU 1 suppository 2 times a day every 12 hours. The course of treatment is 10 days or more for recurrent infections. It is recommended to begin treatment immediately when the first signs of damage to the skin and mucous membranes appear (itching, burning, redness). When treating recurrent herpes, it is advisable to start treatment at prodromal period or at the very beginning of signs of relapse.
U pregnant women with urogenital infection, including herpetic, in the second trimester of pregnancy (starting from the 14th week) - Viferon 500,000 IU 1 suppository every 12 hours (2 times a day) for 10 days, then 1 suppository every 12 hours (2 times a day) twice a week - 10 days. Then, after 4 weeks, preventive courses of the drug Viferon are carried out 150,000 IU 1 suppository every 12 hours for 5 days, the preventive course is repeated every 4 weeks. If necessary, it is possible to carry out treatment course before childbirth.

Separate article. In complex therapy influenza and other acute respiratory infections viral diseases , including those complicated by bacterial infection in adults. VIFERON is used 500000 IU 1 suppository 2 times a day every 12 hours. The course of treatment is 5-10 days.

Contraindications

Increased sensitivity to any of the components of the drug

Pregnancy and lactation

The drug is approved for use from the 14th week of pregnancy. There are no restrictions for use during lactation.

Side effect

In rare cases, it is possible to develop allergic reactions(skin rashes, itching). These phenomena are reversible and disappear 72 hours after stopping the drug.

special instructions

Can be used in the composition combination therapy With antibacterial drugs, GKS, immunosuppressive drugs, interferon inducers.

Overdose

No data provided

Drug interactions

VIFERON, rectal suppositories, is compatible and goes well with all medications used in the treatment of the above diseases (antibiotics, chemotherapy drugs, glucocorticosteroids)

Best before date

2 years. Do not use the drug after the expiration date

Storage conditions

In a dark place, at a temperature from 2 to 8° C. Transportation and storage in accordance with SP 3.3.2.1248-03 at a temperature from 2 to 8º C. Store out of the reach of children

Conditions for dispensing from pharmacies

Without a doctor's prescription

approximate price

Russia: 150,000 IU 5.3-7 $, 500,000 IU 7.9-9.5 $, 1,000,000 IU 10.9-13.8 $, 3,000,000 IU 18.7-21.1 $
Belarus: 150,000 IU 10-14.3 $, 500,000 IU 13.9-19.4 $

Release form: Solid dosage forms. Rectal suppositories.



General characteristics. Compound:

Active substance: 150,000 IU, 500,000 IU, 1,000,000 IU or 3,000,000 IU human recombinant interferon alpha-2b.

Excipients: alpha-tocopherol acetate, ascorbic acid, sodium ascorbate, disodium edetate dihydrate, polysorbate-80, cocoa butter base and confectionery fat.


Pharmacological properties:

Pharmacodynamics. Human recombinant interferon alpha-2b has immunomodulatory, antiviral, and antiproliferative properties. The immunomodulatory properties of interferon, such as increased phagocytic activity of macrophages and increased specific cytotoxicity of lymphocytes to target cells, determine its indirect antibacterial activity.

In the presence of ascorbic acid and alpha-tocopherol acetate, the specific antiviral activity of interferon increases, its immunomodulatory effect is enhanced, which makes it possible to increase the effectiveness of the body's own immune response to pathogenic microorganisms. When using the drug, the level of secretory immunoglobulins of class A increases, the level of immunoglobulin E normalizes, and the functioning of the endogenous interferon system is restored. Ascorbic acid and alpha-tocopherol acetate, being highly active antioxidants, have anti-inflammatory, membrane stabilizing, and regenerating properties. It has been established that when using Viferon there are no side effects that occur with parenteral administration of interferon preparations, no antibodies are formed that neutralize the antiviral activity of interferon.

The use of the drug allows you to reduce the therapeutic doses of antibacterial and hormonal drugs, as well as reduce the toxic effects of this therapy.

Cocoa butter contains phospholipids, which make it possible not to use synthetic toxic emulsifiers in production, but the presence of polyunsaturated fatty acids facilitates the administration and dissolution of the drug.

Indications for use:

— acute respiratory viral infections, including those complicated by a bacterial infection (bacterial, viral, chlamydial) in children and adults as part of complex therapy;
- infectious and inflammatory diseases of newborns, including premature babies: (bacterial, viral), (chlamydia, herpes, candidiasis, including visceral, mycoplasmosis) as part of complex therapy;
— chronic viral hepatitis B, C, D in children and adults as part of complex therapy, including in combination with the use of chronic viral hepatitis of pronounced activity, complicated by cirrhosis of the liver;
- infectious and inflammatory diseases of the urogenital tract (chlamydia, cytomegalovirus infection, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults as part of complex therapy;
- primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild to moderate course, including the urogenital form in adults.


Important! Get acquainted with the treatment, ,

Directions for use and dosage:

The drug is administered rectally. 1 suppository contains human recombinant interferon alpha-2b as an active substance in the indicated dosages (150,000 IU, 500,000 IU, 1,000,000 IU, 3,000,000 IU).

Acute respiratory viral infections, including influenza, including those complicated by bacterial infection, pneumonia (bacterial, viral, chlamydial) in children and adults as part of complex therapy.Recommended dose for adults, including pregnant women and children over 7 years old VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 5 days. According to clinical indications, therapy can be continued.

Children under 7 years of age, including newborns and premature infants with a gestational age of more than 34 weeks, are recommended to use the drugVIFERON® 150,000 IU, 1 suppository 2 times a day every 12 hours every day for 5 days. According to clinical indications, therapy can be continued. The break between courses is 5 days.

Premature newborns with a gestational age of less than 34 weeks are recommended to use the drug VIFERON® 150,000 IU1 suppository 3 times a day after 8 hours every day for 5 days.According to clinical indications, therapy can be continued. The break between courses is 5 days.

Infectious and inflammatory diseases of newborns, including premature babies: meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, cytomegalovirus infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis) as part of complex therapy.The recommended dose for newborns, including premature babies with a gestational age of more than 34 weeks, is VIFERON® 150,000 IU daily, 1 suppository 2 times a day after 12 hours. The course of treatment is 5 days.

Premature newborns with a gestational age of less than 34 weeks are recommended to use the drug VIFERON® 150,000 IU daily, 1 suppository 3 times a day after 8 hours. The course of treatment is 5 days.

Recommended number of courses for various infectious and inflammatory diseases: sepsis - 2-3 courses, meningitis - 1-2 courses, herpes infection - 2 courses, enterovirus infection - 1-2 courses, cytomegalovirus infection - 2-3 courses, mycoplasmosis, candidiasis, including visceral - 2-3 courses. The break between courses is 5 days. According to clinical indications, therapy can be continued.

Chronic viral hepatitis B, C, D in children and adults as part of complex therapy, including in combination with the use of plasmapheresis and hemosorption for chronic viral hepatitis of pronounced activity, complicated by cirrhosis of the liver.The recommended dose for adults is VIFERON® 3,000,000 IU, 1 suppository 2 times a day every 12 hours every day for 10 days, then three times a week every other day for 6-12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.

For children aged 1 to 7 years, 3,000,000 IU per 1 m2 of body surface area per day is recommended.

The drug is used 2 times a day every 12 hours for the first 10 days, then three times a week every other day for 6-12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.

Calculation daily dose The drug for each patient is made by multiplying the recommended dose for a given age by the body surface area calculated using the nomogram for calculating body surface area by height and weight according to Garford, Terry and Rourke. The calculation of a single dose is carried out by dividing the calculated daily dose into 2 administrations, the resulting value is rounded up to the dosage of the suppository.

In case of chronic viral hepatitis of pronounced activity and cirrhosis of the liver, before plasmapheresis and/or hemosorption, it is recommended to use VIFERON® 150,000 IU for children under 7 years of age, VIFERON® 500,000 IU for children over 7 years of age, 1 suppository 2 times a day every 12 hours. within 14 days.

Infectious and inflammatory diseases of the urogenital tract (chlamydia, cytomegalovirus infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults, including pregnant women as part of complex therapy.The recommended dose for adults is VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 5-10 days. According to clinical indications, therapy can be continued.

2 times a day after 12 hours every day for 10 days, then for 9 days 3 times with an interval of 3 days (on the fourth day) 1 suppository 2 times a day after 12 hours. Then every 4 weeks until delivery VIFERON® 150,000 IU1 suppository 2 times a day every 12 hours every day for 5 days.

If necessary, before delivery (from the 38th week of gestation), the use of the drug VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 10 days.

Primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild to moderate course, including the urogenital form in adults, including pregnant women.The recommended dose for adults is VIFERON® 1,000,000 IU, 1 suppository 2 times a day every 12 hours every day for 10 days or more for recurrent infections. According to clinical indications, therapy can be continued. It is recommended to begin treatment immediately when the first signs of damage to the skin and mucous membranes appear (itching, burning, redness).

When treating recurrent herpes, it is advisable to begin treatment in the prodromal period or at the very beginning of signs of relapse.

Pregnant women from the second trimester of pregnancy (starting from the 14th week of gestation) are recommended to use the drug VIFERON® 500,000 IU, 1 suppository2 times a day after 12 hours every day for 10 days, then for 9 days 3 times with an interval of 3 days (on the fourth day) 1 suppository 2 times a day after 12 hours. Then every 4 weeks until delivery VIFERON® 150,000 IU, 1 suppository 2 times a day after 12 hours every day for 5 days. If necessary, before delivery (from the 38th week of gestation), the use of the drug VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 10 days.

Dosage regimen

Gestation week*

Application diagram

From the 14th week of gestation VIFERON® 500,000 IU, 1 suppository 2 times a day for 10 days. Next VIFERON® 500,000 IU, 1 suppository 2 times a day after 3 days, 3 times for 9 days.

Step 1.
C + C (morning/evening)
VIFERON® 500,000 IU

Step 2.
C + C (morning/evening)
VIFERON® 150,000 IU

20, 24

28, 32

36, 40

From the 38th week of gestation until delivery VIFERON® 500,000 IU, 1 suppository 2 times a day for 10 days.

C + C (morning/evening)
VIFERON® 500,000 IU

Features of application:

Effect on ability to drive vehicles and engage in other activities. Not installed.

Use during pregnancy and breastfeeding: The drug is approved for use from the 14th week of pregnancy. There are no restrictions for use during breastfeeding.

Side effects:

In rare cases, allergic reactions (skin rashes, itching) may develop. These phenomena are reversible and disappear 72 hours after stopping the drug.

Interaction with other drugs:

VIFERON®, rectal suppositories, is compatible and goes well with all medications used in the treatment of the above diseases (antibiotics, chemotherapy drugs, glucocorticosteroids).

Contraindications:

Hypersensitivity to any of the components of the drug.

Overdose:

Not installed.

Storage conditions:

At a temperature of 2 to 8 ° C, in a place protected from light. Keep out of the reach of children. Shelf life - 2 years. Do not use the drug after the expiration date.

Vacation conditions:

Over the counter

Package:

Rectal suppositories 150,000 IU, 500,000 IU, 1,000,000 IU, 3,000,000 IU. 5 or 10 suppositories in PVC/PVC blister packs. 1 blister pack of 10 suppositories or 2 blister packs of 5 suppositories with instructions for use in a cardboard pack.