Calcium chloride method of application. Calcium chloride - a time-tested drug

Composition and form of release of the drug

Solution for intravenous administration colorless, transparent.

Excipients: water for injection - up to 1 ml.

5 ml - colorless glass ampoules (5) - blister packs (1) - cardboard packs.
5 ml - colorless glass ampoules (5) - blister packs (2) - cardboard packs.
5 ml - colorless glass ampoules (5) - blister packs (1) complete with ampoule scarifier or ampoule knife - cardboard packs.
5 ml - colorless glass ampoules (5) - blister packs (2) complete with ampoule scarifier or ampoule knife - cardboard packs.
5 ml - colorless glass ampoules (5) - cardboard trays (1) - cardboard packs.
5 ml - colorless glass ampoules (5) - cardboard trays (2) - cardboard packs.
5 ml - colorless glass ampoules (5) - cardboard trays (1) complete with ampoule scarifier or ampoule knife - cardboard packs.
5 ml - colorless glass ampoules (5) - cardboard trays (2) complete with ampoule scarifier or ampoule knife - cardboard packs.
10 ml - colorless glass ampoules (5) - blister packs (1) - cardboard packs.
10 ml - colorless glass ampoules (5) - blister packs (2) - cardboard packs.
10 ml - colorless glass ampoules (5) - blister packs (1) complete with ampoule scarifier or ampoule knife - cardboard packs.
10 ml - colorless glass ampoules (5) - blister packs (2) complete with ampoule scarifier or ampoule knife - cardboard packs.
10 ml - colorless glass ampoules (5) - cardboard trays (1) - cardboard packs.
10 ml - colorless glass ampoules (5) - cardboard trays (2) - cardboard packs.
10 ml - colorless glass ampoules (5) - cardboard trays (1) complete with ampoule scarifier or ampoule knife - cardboard packs.
10 ml - colorless glass ampoules (5) - cardboard trays (2) complete with ampoule scarifier or ampoule knife - cardboard packs.

pharmachologic effect

Calcium is a macronutrient involved in the formation bone tissue, the process of blood coagulation, is necessary to maintain stable cardiac activity, transmission processes nerve impulses. Improves muscle contraction in muscular dystrophy, myasthenia gravis, reduces vascular permeability. When administered intravenously, calcium stimulates the sympathetic nervous system and increased adrenal secretion; has a moderate diuretic effect.

When a calcium chloride solution interacts with magnesium salts, oxalic and fluoric acids, insoluble compounds are formed, which makes it possible to use a calcium chloride solution as an antidote.

Indications

As an additional remedy in the treatment of allergic diseases (incl. serum sickness, urticaria, angioedema, ) and allergic reactions for medicines. As an additional hemostatic agent for pulmonary, gastrointestinal, nasal, uterine bleeding. As an antidote for poisoning with magnesium salts, oxalic acid and its soluble salts, as well as soluble salts of fluoric acid.

Contraindications

Dosage

With / in the introduction single dose is 0.5-1 mg. When taken orally, a single dose is 0.25-1.5 g. The frequency and duration of use depend on the indications and the clinical situation.

Side effects

Maybe: bradycardia; with rapid introduction - ventricular fibrillation; with a / in the introduction - a feeling of heat in the mouth, and then throughout the body.

drug interaction

Calcium chloride is incompatible with salts of lead, silver, monovalent mercury due to the formation of insoluble chlorides heavy metals and with sodium barbital, tk. in this case, a sparingly soluble calcium salt of barbital is formed.

Calcium chloride at simultaneous application reduces action. Under the influence of cholestyramine, calcium absorption from the gastrointestinal tract is reduced. With simultaneous use with quinidine, it is possible to slow intraventricular conduction and increase the toxicity of quinidine. During treatment with cardiac glycosides parenteral administration calcium chloride is not recommended due to increased cardiotoxicity.

special instructions

Do not enter s / c and / m. If calcium chloride gets under the skin or in muscle tissues severe irritation develops with the formation of foci of necrosis.

Chloride, having a liquid substance, is well absorbed into bloodstream. Therapeutic action the drug begins almost immediately after the drug enters the bloodstream. This is its main value.

The content of chloride allows you to remove the intoxication of the body various origins. The mechanism of action of the drug is as follows:

  • Adrenaline is intensely produced;
  • The nervous system is stimulated;
  • Inflammatory processes are reduced;
  • The edema is removed.
  • Pollinosis or allergies to pollen and flowering;
  • allergic dermatitis;
  • Allergies to drugs;
  • Allergies to vaccinations;
  • serum sickness;
  • Quincke's edema;
  • Allergies to protein.

Calcium chloride it will also be useful for children with allergies. But, because of its bitter taste, children refuse to take it. When urgent need, the children's dose is prescribed and controlled only by the attending physician, since the drug, like any drug, has contraindications.

Calcium chloride for allergies: instructions

Despite the fact that the drug does not belong to the main anti-allergic treatments, it is used in complex therapy. Although the form of its release in the form of injectable capsules, you can also drink calcium chloride with allergies. In this case, the contents of the injection are poured into a tablespoon and taken orally with plain water. Calcium chloride inside with allergies is taken only if it is prescribed by a doctor. When using, be sure to observe the indicated dosage and time of use of the drug.

Intravenous injections of drugs are able to remove in a matter of minutes acute attacks severe allergies, in particular Quincke's edema. The timely introduction of chloride saved more than one human life from its own suffocation.

Intravenously, the drug is administered very slowly, on average 1 ml. within 1 min. In the first minutes after the start of administration, the patient begins to have a fever in the mouth and mucous membranes of the genital organs. This is a natural effect that is characteristic this drug. The symptoms of fever pass quickly and do not leave behind any complications.

The safest and no less effective method the use of calcium chloride - electrophoresis procedures with this drug. Substances of chloride under the influence of electric current penetrate the skin into the body, contributing to effective removal inflammation and swelling.

What are the contraindications of calcium chloride?

It is contraindicated to administer the drug intramuscularly or subcutaneously. Such negligence can end sadly for soft tissues. As a result, necrosis occurs, and then an abscess.

In no case should calcium chloride be used by patients with atherosclerosis, thrombophlebitis, as well as those who have higher level calcium.

Side effects when internal application can also be: pain syndrome in the stomach and heartburn.

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What is calcium chloride

Calcium Chloride has chemical formula CaCl2. To understand what calcium chloride is and how it works, you need to consider the properties. It has an orthorhombic crystalline molecular shape. The substance turns into a hexahydrate - solid in structure, then becomes liquid. Calcium chloride is obtained under technical conditions in the production of soda or berthollet salt. Second Recipe: Interaction of hydrochloric acid and calcium carbonate or hydroxide. The powder dissolves in acetone or lower alcohols, absorbs water, cooling it.

Calcium chloride - instructions for use

The tool is widely used in medicine. The release form is a colorless liquid in ampoules. Indications prescribe its use intravenously, orally, or by electrophoresis. The use of calcium chloride, according to the instructions, is beneficial for certain ailments:

  • with allergies and complications associated with a reaction to other medicines;
  • deficiency of calcium in the body;
  • with bronchial asthma;
  • hay fever;
  • toxic pulmonary edema and other inflammatory processes;
  • radiation sickness;
  • with eczema;
  • hepatitis;
  • jade;
  • with psoriasis;
  • renders diuretic effect, like ammonium chloride;
  • with bleeding of various origins (to increase clotting);
  • to relieve symptoms of poisoning;
  • for local application electrophoresis is used with this substance, which has an astringent, anti-inflammatory, firming and soothing effect.

You can find the remedy at free access at any pharmacy. However, it is strictly forbidden to administer the drug inside without a doctor's prescription and supervision, as this can cause significant harm to health. At home, the drug is allowed to be used for the manufacture cosmetic products: masks, scrubs, add to shampoos or balms.

Calcium chloride intravenously

The drug can be administered by injection or dropper. For the use of calcium chloride intravenously, the prescribed amount of the drug from the ampoule should be diluted with 100-200 ml of glucose or sodium chloride solution (0.9%). Before introducing the resulting liquid into the blood, you need to warm it up to a temperature human body. The procedure should be slow, an increase in speed can cause damage to blood vessels, cardiac arrest.

The injection process can be characterized by a decrease in pressure, nausea, a taste of chalk, fever (therefore, the procedure is called a “hot injection”), fainting, and arrhythmia. If the patient begins to feel pain or redness appears on the skin, the use of the drug should be stopped immediately. After the procedure, the patient needs a twenty-minute rest under the supervision of a doctor.

calcium chloride intramuscularly

On the shelves of pharmacies it is impossible to find a solution of this injection. This fact is explained by the fact that it is strictly forbidden to administer calcium chloride intramuscularly or subcutaneously. Such a procedure can lead to the following consequences:

  • the strongest irritation;
  • necrosis and tissue death at the injection site.

Calcium chloride for oral administration

Some categories of citizens, for example, children, are not recommended for intravenous administration. For such people, calcium chloride for oral administration is suitable. Adults should take 1 tbsp. l. twice a day after meals. Children are prescribed the use of calcium chloride inside for 1-2 tsp. after meal. When hit in digestive system the drug can cause heartburn and pain in the epigastric region.

Peeling with calcium chloride at home

it medical device in liquid form, it is used in cosmetology to get rid of impurities and dead skin cells, acne. Facial cleansing with calcium chloride at home - step by step instructions:

  1. The first step should be to cleanse your face of makeup.
  2. On cleaned skin apply foam from baby soap which does not contain fragrances and other harmful additives.
  3. Take a small container, pour the contents of the calcium chloride ampoule inside. Gradually apply the product with your fingers on the face. Rub lightly until lumps form. Do not treat areas around the eyes and lips.
  4. After small lumps have formed, continue for a short time light massage movements until a creak appears.
  5. To remove the remaining product from the face, use a napkin, then wash with warm water.
  6. At the end of the procedure, treat your face with a moisturizer.

Calcium chloride for hair

If you have problems with hair, experts recommend saturating habitual means useful substances or make masks with them. You can buy the necessary medicines at the pharmacy. Calcium chloride for hair is great helper at strong fallout, strengthens them and stimulates growth. The medicine should be used separately from other vitamin medicines. You can use it by adding a large number of in shampoo and balm or homemade masks. Conduct medical procedure required twice a week, a course of 15-20 sessions.

A simple mask using this drug:

  1. Take a small bowl, lay out 1 tbsp. l. balm or hair mask that you are used to using.
  2. Pour an ampoule of calcium chloride inside, stir the ingredients until smooth.
  3. Apply the substance to wet and clean hair, put on a plastic cap, wrap a towel on top. Leave to act for 30-40 minutes.
  4. Wash off with warm water.

Calcium chloride - contraindications

It is better to coordinate any use of the drug with a doctor, since the medicine can be harmful. Calcium chloride - contraindications:

  • severe atherosclerosis;
  • the child should not be administered intravenously;
  • tendency to form blood clots;
  • the calcium content in the blood is higher than normal;
  • if you are using a peeling preparation, you should not sunbathe for a couple of days after the procedure.

The price of calcium chloride

Clear solution for intravenous injections can be purchased in Moscow pharmacies or bought in the online store according to the catalog without leaving home. Prices for medicines do not differ significantly. The indicator depends on the volume of ampoules and the manufacturer. However, before you order online, make sure you don't have to pay shipping costs. The approximate price for calcium chloride is shown in the table.

Video: calcium chloride peeling at home

Reviews

Alena, 27 years old

What is calcium chloride, I learned after an unsuccessful visit to the dentist. At home, I discovered that gums goes blood. How to stop it, asked the doctor. The doctor advised me to buy this drug because it affects blood clotting. I managed to buy it inexpensively, and I had to drink only 1 spoon to stop the bleeding.

Rimma, 40 years old

I have suffered from oily skin and enlarged pores since I was a teenager. A soap scrub with a 10% solution of this medicine helps me put myself in order. Learned about this Hollywood way cleaning on the review of a friend. The procedure is much cheaper, because the composition has an affordable price, and I am very pleased with the result.

Alexey, 32 years old

I first saw this name in a review about the treatment of pneumonia. Having fallen ill himself, he tried to use it on the advice of a doctor. I was given injections into a vein. The cough went away quickly - in a few days. The specialist explained that the properties of the remedy perfectly help to eliminate inflammation. I was surprised by its price. Today you rarely see medicines under 50 rubles.

sovets.net

Composition and form of release

A drug with a tonic, anti-allergic, anti-inflammatory effect is a clear liquid for intravenous administration or oral administration. The drug solution is in ampoules, the concentration is 10%, the volume of the drug in each container is 5 or 10 ml. Excipient- water for injections. The carton contains 10 ampoules.

Action

Subject to the rules of use, the drug gives a noticeable therapeutic effect:

  • metabolic processes are normalized;
  • reduces the risk of seizures against the background of calcium deficiency;
  • the permeability of cells and the vascular wall decreases;
  • the patient recovers more quickly after a serious illness;
  • a moderate diuretic effect is manifested;
  • the sensitivity of the body to the influence of stimuli decreases;
  • inflammatory processes develop less frequently;
  • it is more difficult for infectious agents to act in the body;
  • The adrenal glands secrete more epinephrines.

Learn about first aid anaphylactic shock and further treatment.

Effective treatments for eyelid allergies are described here.

At complex treatment allergic diseases are manifested positive action drug:

  • rashes of a different nature disappear;
  • tissue swelling decreases;
  • the flow of adrenaline into the blood increases, the work of the nervous system is stimulated;
  • the condition is normalized with allergies of varying severity.

About half the volume active substance binds to blood plasma. Residues of the drug are excreted through the intestines (80%) and in the urine (less than 20%).

Calcium chloride: indications for use

The drug is recommended as part of the complex therapy of many allergic diseases. Required condition- a combination of calcium chloride and modern antihistamines: Loratadine, Claritin, Erius, Fenistil, Cetirizine. "Hot injections" and the use of the solution inside have a positive effect on the condition of allergy sufferers.

Indications for appointment medicinal solution:

  • allergies to antibiotics and other medicines of various kinds;
  • hay fever;
  • angioedema;
  • allergic dermatoses;
  • urticaria of a different nature;
  • acute response to the administration of serum proteins.

  • calcium deficiency in food;
  • hypocalcemia;
  • osteomalacia;
  • bleeding of a different nature;
  • conditions in which the level of Ca drops sharply;
  • nephritis;
  • hepatitis;
  • breastfeeding period (on the recommendation of a gynecologist and therapist);
  • toxic effects of oxalic and fluoric acids, magnesium salts;
  • pulmonary tuberculosis;
  • period of menopause.

Contraindications

The drug is not suitable for patients with the following diseases:

  • atherosclerosis (severe stage);
  • urolithiasis disease;
  • thrombosis;
  • pregnancy;
  • excessive sensitivity to the active substance;
  • high concentration of calcium ions in the blood;
  • renal failure (chronic form);
  • sarcoidosis.

You should not take calcium chloride against the background of the inclusion of cardiac glycosides in the list of therapeutic agents. The result of a combination of two types of drugs is a cardiotoxic effect.

The main types of intake during therapy:

  • intravenously (stream or drip);
  • oral intake;
  • during electrophoresis.

Children are allowed only one method of use - the use of a medicinal solution inside. All forms are suitable for adults: the choice of method is carried out by the attending physician.

  • intravenous administration. The procedure is popularly known as hot shot» calcium chloride. To dilute the composition, sodium chloride, a solution of glucose (dextrose) are used. The injections are done by a health worker. Features of the introduction of calcium chloride: it is important to inject the drug into the vein slowly, no more than 1.5 ml per minute. For one procedure, the volume of the drug should not exceed 3 ampoules. Violation of the rules negatively affects the heart, up to its stop. After the procedure, the patient is under the supervision of a specialist for 15-20 minutes, the “lying” position is mandatory. It is impossible to get up abruptly after the procedure: arrhythmia, fainting, a sharp decrease in pressure are possible;
  • oral intake. For internal use, the doctor prescribes a solution of a concentration of 5 or 10%. Take the drug only after meals. Important point- adherence to the dosage: children - 0.3 ml of the drug per 1 kg of body weight, maximum 10 ml per day. Daily dosage for adults - no more than 15 ml, for children under 12 months - no more than 0.5 ml per day. The optimal frequency of oral calcium chloride intake is two to three times during the day.

Side effects

Patients tolerate well the intake and intravenous administration of calcium chloride. A prerequisite for risk minimization negative reactions- compliance with the rules of application.

Discomfort during procedures is expressed in the following signs:

  • redness of the skin of the face, a feeling of heat;
  • low heart rate;
  • too fast a rate of drug administration causes ventricular fibrillation of the heart;
  • oral intake of calcium chloride sometimes causes heartburn, pain in the epigastrium;
  • some patients feel an unpleasant tingling along the vein into which the active solution is injected.

drug interaction

Useful information about the effect of calcium chloride:

  • combination with digoxin, antibiotics of the tetracycline group, iron preparations reduces the absorption of these drugs. The optimal interval between taking a solution of calcium chloride and these items is at least two hours;
  • simultaneous reception with thiazide diuretics provokes hypercalcemia, reduces the level of bioavailability of phenytoin.

Calcium chloride - inexpensive drug for complex therapy of allergic reactions. Depending on the volume of the ampoule (5 or 10 ml), package No. 10 costs from 30 to 105 rubles. The price of calcium chloride varies markedly depending on the manufacturer.

Find out the instructions for using Ketotifen tablets for children and adults.

For a list and description of drugs for urticaria in adults, see this page.

Go to http://allergiinet.com/zabolevaniya/u-vzroslyh/vaskulit.html and read about the symptoms and treatment of allergic vasculitis.

Additional Information

During treatment with calcium chloride, the attending physician should inform the patient about the effect of the drug on the body. It is forbidden to independently inject the drug solution: violation of the rules, excessive concentration active ingredient(5% or more), the rate of administration often causes tissue necrosis.

On a note:

  • it is forbidden to administer calcium chloride subcutaneously or intramuscularly: possible severe irritation, tissue death;
  • at intravenous administration the patient feels heat in the mouth, then the heat spreads to other parts of the body;
  • when injected into a vein, pain is possible along the vessels, redness of the tissues;
  • the drug is sold in pharmacies without a prescription, but doctors categorically do not advise taking the medicinal solution on their own. Non-compliance with the dosage often provokes severe side effects, a violation of the volume or concentration of the drug is dangerous for patients, especially children;
  • when there is a fever, discomfort, many people panic, get up from the couch, take pills for fever. Wrong actions are often harmful cardiovascular system. Health worker supervision reduces risk side effects: the specialist will tell the patient how to behave after a “hot injection” or oral intake, what sensations should not be frightening, and under what phenomena it will be necessary urgent help doctor.

The patient must observe the temperature regime for storing the medicinal solution: from +15 to 25 degrees. It is forbidden to freeze containers with the drug: the composition loses its active properties. Be sure to keep the drug ampoules away from sunlight and heating appliances. The solution for oral and intravenous administration is suitable for five years.

Analogues

Other names are suitable for resupplying Ca. Many medicines are more expensive than calcium chloride. Choice of funds and best method application is carried out by a doctor.

Ca preparations with a similar effect:

  • Latoxyl.
  • Glucosil.
  • Sodium chloride.
  • Reamberin.
  • Xylat.
  • Magnesium sulfate.

Reviews

Many patients notice a significant improvement in their condition after "hot injections" and internal reception medicinal solution. Therapeutic effect often noticeable after the first treatment.

Not a very pleasant moment - a feeling of heat in the whole body, discomfort, a rush of blood to the face during the procedure. If the rules for administering the composition are violated, temporary problems with cardiac activity often appear, indicators are violated blood pressure. If the instructions are followed exactly, the benefits of taking calcium chloride or "hot shot" are much greater than the discomfort during treatment.

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pharmachologic effect

Calcium chloride compensates for the lack of calcium in the body - important element, which takes part in the activity of the myocardium, the formation of bone tissue, blood coagulation, muscle contraction.

The drug reduces the permeability of the vascular wall, cells, prevents inflammation, increases resistance to infections, enhances the release of epinephrine by the adrenal glands.

There is good feedback o Calcium chloride, that when administered intravenously, the agent stimulates sympathetic department nervous vegetative system, has a moderate diuretic effect.

Release form

Calcium chloride is released in ampoules of 5 and 10 ml with a solution for internal use, intravenous administration.

Indications for use Calcium chloride

A solution of calcium chloride is prescribed in conditions characterized by an increased need for calcium - a period of increased growth, pregnancy, lactation.

Calcium chloride is effective for bleeding of various origins and localizations, with allergic diseases(urticaria, itching, serum sickness, angioedema, fever), bronchial asthma, alimentary dystrophic edema, tetany, spasmophilia, rickets, osteomalacia, lead colic, pulmonary tuberculosis, hypocalcemia, hypoparathyroidism, radiation sickness, hemorrhagic vasculitis, toxic and parenchymal hepatitis , nephritis, eclampsia, paroxysmal myoplegia, inflammatory and exudative processes, psoriasis, eczema.

There is positive reviews about calcium chloride used for weakness labor activity, poisoning with magnesium salts, fluoric, oxalic acids

Mode of application

Intravenous administration of the solution is carried out slowly (6-8 drops / min). Enter 1-3 ampoules of calcium chloride with a 10% solution, diluting it with 100-200 ml of sodium chloride solution or 5% dextrose solution.

Inside, the remedy is taken after meals two to three times a day. Usually drink 5-10% solution. Adults should take 10-15 ml at a time, children - 5-10 ml.

In cosmetology, calcium chloride is used for peeling. oily skin. For the procedure, apply twice to the face, wait for it to dry and wash off the solution with soap. Dead cells will roll off the face in lumps, and the face is washed until they are all washed off.

Side effects

The remedy for internal use can cause pain in the epigastric region, heartburn. With intravenous administration, there may be a feeling of heat, a decrease in heart contractions. Rapid administration of the drug can lead to non-rhythmic contractions of the heart ventricles.

Contraindications to the use of calcium chloride

Calcium chloride is not prescribed for severe atherosclerosis, with elevated content in the blood of calcium, with a predisposition to thrombosis.

You can not simultaneously take the drug with phosphates, salts, salicylates, carbonates, sulfates.

During treatment, it should be borne in mind that the drug reduces the absorption of tetracyclines, oral medications iron, digoxin. With simultaneous use with thiazide diuretics, hypercalcemia may increase, the effectiveness of calcitonin in this disease and the bioavailability of phenytoin may decrease.

After peeling with calcium chloride, you should not sunbathe for two to three days.

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The composition of the drug and the form of its release

Calcium chloride is available as a colorless clear liquid for intravenous administration. The solution contains 100 mg of calcium chloride per 1 ml.

Indications for use

Calcium chloride not only has a very beneficial effect on the functioning of all body systems, its intake is also able to prevent tissue inflammation and increase resistance to different kind infections, thereby minimizing the harm they can cause human body. So the possibilities of using this tool in medicine are very numerous.

Most often, calcium supplements are prescribed for the following indications:

  • Treatment of hepatitis and nephritis;
  • Various dermatological diseases;
  • Increased human need for calcium;
  • Poisoning with magnesium and fluorine salts, as well as oxalic acid;
  • Finding for a long time in an immobilized state;
  • Weakness of labor activity;
  • Allergies (eg. hay fever, urticaria, allergic dermatosis);
  • Acute blood loss with pulmonary, uterine, gastrointestinal and nasal bleeding;
  • postoperative period.

Calcium chloride is also used for washing at home wounds, mucous membranes of the eyes, and is part of the solvents for various pharmacological preparations.

Contraindications for use

  • Chronic renal failure;
  • Tendency to thrombosis;
  • Urolithiasis disease;
  • Severe atherosclerosis;
  • Simultaneous administration of cardiac glycosides with it (the use of a calcium chloride preparation is not recommended, since the cardiotoxic effect of the drugs is enhanced);
  • Hypersensitivity to the components of the drug;
  • Sarcoidosis;
  • Pregnancy, as well as lactation - breastfeeding (if calcium chloride is necessary during lactation, breast-feeding stops).

The ability to drive vehicles is not affected by the intake of calcium chloride.

Ways to use

Instructions for use of calcium chloride indicate that the drug can be used different ways. It can be administered intravenously (drip or jet) or taken orally, it is also possible to introduce it into the body using electrophoresis through the skin - a direct hit of the drug into the muscle or subcutaneous tissue can bring significant harm to health - severe local irritation and even necrosis of surrounding tissues.

In cases where intravenous administration of the drug is prescribed, calcium chloride must be diluted in 100–200 ml with a 5% dextrose (glucose) solution or 0.9% sodium chloride solution.

The resulting solution is heated to body temperature before being injected into the blood. The injection is made slowly - no more than 0.75-1.5 ml (that is, a maximum of 8 drops) per minute. If you make an injection quickly, the state of cardio-vascular system tangible harm can be done, up to cardiac arrest.

With intravenous administration of calcium chloride, the patient feels heat throughout the body (popularly called a "hot injection") and a taste of chalk in the mouth. Also, it is possible to lower blood pressure, nausea, arrhythmia and fainting.

If during the procedure there is redness at the injection site or the patient feels pain, the drug should be stopped.

After the injection is made, the patient should remain for some time (no more than 20 minutes) under the supervision of a doctor in the supine position. Usually up to 3 ampoules are administered per injection.

As a rule, intravenous calcium chloride is prescribed only for adults. The child should take a solution of calcium chloride exclusively inside.

Calcium chloride solution should be drunk after meals, maximum daily dose, which in no case should be exceeded, for children - 15 milliliters (0.3 ml per 1 kg of weight), so as not to harm an overdose of the drug, and for adults - 10-15 milliliters of the drug. As a rule, a five or ten percent solution of the drug is prescribed for internal use.

Storage conditions and expiration dates

The shelf life of the calcium chloride preparation is 5 years at proper storage, including at home, - in a dark place at an air temperature of no more than 25 degrees.

Although calcium chloride is freely sold in pharmacies, and in each package with the drug there is an instruction that indicates all doses, contraindications, composition, is described possible harm if used incorrectly, it is still strongly not recommended to take it for treatment at home on your own. At home, you can use a solution of calcium chloride only for external use, so as not to harm your health.

Antihistamines of the latest generation

We all know how many different chemical elements in nature, not to mention the different compounds of them. Take, for example, calcium chloride. A substance with a modest name has quite a lot options applications. Below we will give examples of its use, and now we will focus on general idea about what is calcium chloride. The instructions for using this substance each time, of course, are different. We will also pay attention to this.

General description and some characteristics of calcium chloride

The chemical formula of the substance under discussion is CaCl 2. It represents rhombic crystals with the following lattice parameters: a = 6.24 Å, b = 6.43 Å, c = 4.20 Å. The boiling point is 1600 ° C, the melting point is 772 °, the density is 2.512 g / cm3. Calcium chloride strongly absorbs water vapor and is very hygroscopic. First, it forms solid hydrates, and subsequently it spreads into a liquid. In an anhydrous form, it dissolves in water with significant heat release. It dissolves in acetone, as well as in liquid ammonia and lower alcohols, forming solvates with them. Get this stuff like by-product during the production of soda using the ammonia method or in the production of KClO 3 - Bartolet's salt.

Calcium chloride: instructions for use in medicine

One of the important applications of calcium chloride is its use in medicine. It is prescribed intravenously for hypochloremia, hyponatremia, dehydration, manifested as a result of toxic dyspepsia, in shock, acute blood loss, indomitable vomiting, in the period after surgery.

It is also used externally: for washing mucous membranes, eyes, wounds. Used as a solvent for various medical preparations. Calcium chloride is produced in the form of a solution for injection, in 1 ml - 100 mg. Thanks to calcium ions, the effect of the drug is ensured. Calcium plays in the body important role in the reduction of smooth and skeletal muscle, the transmission of nerve impulses, the formation of bone tissue, blood coagulation, etc. CaCl 2 solution is used as an antidote due to the formation of insoluble compounds. In allergic diseases such as hay fever, angioedema, urticaria, serum sickness and others, this drug is also used as aid. In case of poisoning with oxalic acid, magnesium salts and fluoric acid - as an antidote. With gastrointestinal, pulmonary, uterine and nasal bleeding - as a hemostatic agent. Calcium chloride in medicine is administered intravenously slowly, in a stream, for 3-5 minutes. Dose - 5 ml. The second option is drip. In this case, dilute 5-10 ml of the drug in 5% glucose solution or in 100-200 ml isotonic solution sodium chloride. It is necessary to observe the rate of administration - 6 drops per minute. Possible side effect- with rapid administration, bradycardia may occur. It can not be used with a person's tendency to thrombosis, hypercalcemia and atherosclerosis.

Where else is calcium chloride used: detailed information

If you ask a hundred people about the uses of this substance, approximately 10% will answer that it is a winter de-icing agent used for treating roads and sidewalks. There will be those who do not know the other purpose of CaCl 2, except for waterproofing liquid rubber. Others will argue that this substance is used as important component flushing fluids for drilling or when constructing oil wells - as a component of the cement slurry. Where else is calcium chloride needed? Instructions for use may surprise you. It is widely used in the construction industry. For example, it minimizes the hardening time of concrete by several times, and is a good accelerator of the cement hydration process. In addition, it enhances the wear resistance and strength of concrete even when it is poured in winter. These same abilities make it possible to increase the frost resistance and strength of silicate bricks.

A little-known application of CaCl 2

Due to the fact that this compound has the ability to dissolve well in water, a solution of such a substance as calcium chloride has also become widespread.

Its application has spread to many other industries. It is used:

  1. in metallurgy.
  2. In the manufacture of reagents - in the chemical industry.
  3. In the production of pulp and paper.
  4. in the mining industry.
  5. In the production of automobile tires and rubber.

used as food supplement E509, in the production of cheese, cottage cheese, jelly, jams, canning fruits and vegetables, freezing products calcium chloride. Instructions for use can tell you about food with his "participation". Finally, we note the use of calcium chloride for peeling in cosmetology and as an anti-allergic, anti-inflammatory and

Name:

Calcium chloride (Calcii chloridum)

Pharmacological
action:

Calcium - macronutrient, involved in the formation of bone tissue, the process of blood coagulation, is necessary to maintain stable cardiac activity, the processes of transmission of nerve impulses.
Improves muscle contraction in muscular dystrophy, myasthenia gravis, reduces vascular permeability.
When administered intravenously, calcium causes excitation of the sympathetic nervous system and increased release of adrenaline by the adrenal glands; has a moderate diuretic effect.
When a calcium chloride solution interacts with magnesium salts, oxalic and fluoric acids, insoluble compounds are formed, which makes it possible to use a calcium chloride solution as an antidote.

Indications for
application:

With insufficient function of the parathyroid glands, accompanied by tetany or spasmophilia (a disease in children associated with a decrease in the content of calcium ions in the blood and scaling of the blood);
- with increased excretion of calcium from the body, which can occur with prolonged immobilization of patients;
- with allergic diseases (serum sickness, urticaria, angioedema, hay fever, etc.) and allergic complications associated with medication. The mechanism of anti-allergic action is unclear, however, it should be noted that intravenous administration of calcium salts causes excitation of the sympathetic nervous system and increased release of adrenaline by the adrenal glands;
- as a means of reducing vascular permeability, with hemorrhagic vasculitis(hemorrhage due to inflammation of the walls blood vessels), phenomena of radiation sickness, inflammatory and exudative processes (discharge from small vessels tissue rich in protein fluid) - pneumonia (inflammation of the lungs), pleurisy (inflammation of the membrane covering the lungs and lining the walls chest cavity), adnexitis (inflammation of the uterine appendages), endometritis (inflammation inner surface uterus), etc.;
- at skin diseases(itching, eczema, psoriasis, etc.). With parenchymal hepatitis (inflammation of the liver tissue), toxic lesions liver (liver damage) harmful substances), nephritis (inflammation of the kidney), eclampsia (severe form of late toxicosis of pregnant women), hyperkalemic form of paroxysmal myoplegia (paroxysmal / periodically occurring / paralysis, occurring with an increase in the content of potassium in the blood);
- as a hemostatic agent for pulmonary, gastrointestinal, nasal, uterine bleeding; in surgical practice, sometimes administered before surgical intervention to increase blood clotting. However, there are no sufficiently reliable data on the hemostatic (hemostatic) effect of calcium salts introduced into the body from the outside; calcium ions are necessary for blood clotting, but the amount of calcium usually contained in blood plasma exceeds the amount needed to convert prothrombin to thrombin (one of the blood clotting factors);
- as an antidote for poisoning with magnesium salts (see magnesium sulfate), oxalic acid and its soluble salts, as well as soluble salts of fluoric acid (when interacting with calcium chloride, non-dissociating / non-decomposing / and non-toxic oxalate and calcium fluoride are formed);
- the drug is also used in combination with other methods and means to stimulate labor.
When taken orally (8-10 g) has a diuretic (diuretic) effect; According to the mechanism of action, it belongs to acid-forming diuretics.

Mode of application:

Prescribe calcium chloride inside, intravenous drip(slowly), intravenous bolus(very slow!) and administered by electrophoresis(percutaneous route of administration) medicinal substances through electric current).
Inside take after meals in the form of a 5-10% solution 2-3 times a day.
Adults are prescribed 10-15 ml per reception (dessert or tablespoon of solution); children - 5-10 ml (tea or dessert spoon).
6 drops per minute are dripped into a vein, diluting 5-10 ml of a 10% solution in 100-200 ml of isotonic sodium chloride solution or 5% glucose solution before administration.
Intravenous jet injected slowly (within 3-5 minutes) 5 ml of a 10% solution. Recommended for the treatment of allergic diseases joint application calcium chloride and antihistamines.

Side effects:

When taking calcium chloride inside, pain in the epigastric region, heartburn are possible;
- when injected into a vein - bradycardia (decreased heart rate);
- with rapid administration, ventricular fibrillation of the heart (chaotic contractions of the heart muscle) may occur;
- with intravenous administration of calcium chloride, a feeling of heat appears first in the oral cavity, and then throughout the body. This feature of the drug was previously used in determining the rate of blood flow; the time between the moment of its introduction into the vein and the appearance of a sensation of heat was determined.

Contraindications:

Solutions of calcium chloride should not be administered subcutaneously or intramuscularly, as they cause severe irritation and necrosis (necrosis) of tissues.
Calcium chloride is contraindicated in case of a tendency to thrombosis (blockage of a vessel with a blood clot), advanced atherosclerosis, and an increased content of calcium in the blood.

Interaction
other medicinal
by other means:

Calcium chloride is incompatible with salts of lead, silver, monovalent mercury due to the formation of insoluble chlorides of heavy metals and with sodium barbital, tk. in this case, a sparingly soluble calcium salt of barbital is formed.
Calcium chloride with simultaneous use reduces the effect of calcium channel blockers. Under the influence of cholestyramine, calcium absorption from the gastrointestinal tract is reduced.
With simultaneous use with quinidine, it is possible to slow intraventricular conduction and increase the toxicity of quinidine.
During treatment with cardiac glycosides, parenteral use of calcium chloride is not recommended, due to increased cardiotoxicity.


A drug calcium chloride- anti-allergic, anti-inflammatory, hemostatic, detoxifying, reducing capillary permeability, agent.
The drug eliminates the deficiency of calcium ions. Calcium ions are involved in the transmission of nerve impulses, the reduction of smooth and skeletal muscles, in functional activities myocardium, blood coagulation; necessary for the formation of bone tissue, the functioning of other systems and organs. The concentration of calcium ions in the blood decreases with many pathological processes, severe hypocalcemia contributes to the occurrence of tetany. Calcium chloride, in addition to eliminating hypocalcemia, reduces vascular permeability, exhibits anti-allergic, anti-inflammatory and hemostatic effects.

Pharmacokinetics

.
In the blood it is in an ionized and bound state.
Physiological activity is inherent ionized calcium. deposited in bone tissue. It is excreted from the body with urine, but mainly with feces.

Indications for use

Function deficiency parathyroid glands(spasmophilia, tetany), increased excretion of calcium from the body (in particular, with prolonged immobility), allergic diseases (angioneurotic edema, urticaria, hay fever, serum sickness), including those caused by the drug; to reduce the permeability of the vascular wall ( radiation sickness, hemorrhagic vasculitis), with pleurisy, pneumonia, endometritis, adnexitis; skin diseases (psoriasis, eczema, itching); with toxic liver damage, parenchymal hepatitis, nephritis; eclampsia; paroxysmal myoplegia (hyperkalemic form).
A drug calcium chloride used for external and internal bleeding, administered as an antidote for poisoning with oxalic acid and its salts, soluble salts of fluoric acid, magnesium salts.
It is also prescribed for complex stimulation of labor, complex treatment (in combination with antiallergic drugs) of allergic diseases.

Mode of application

calcium chloride appoint intravenously stream (very slowly) and intravenously drip (slowly). Intravenous drip: 5-15 ml of the drug is diluted in 100-200 ml of sodium chloride, injection 0.9% or
glucose, injection 5%; administered at a rate of 6 drops per minute 1-3 times a day. Intravenous administration by bolus: 5 ml of the drug is administered over 3-5 minutes.
The duration of the course is determined by the nature, course of the disease, the achieved therapeutic effect.

Side effects:
calcium chloride when administered intravenously, it can cause bradycardia, and when administered rapidly, it can cause ventricular fibrillation.

Contraindications

:
Contraindications to the use of the drug calcium chloride are: thrombosis and a tendency to them, thrombophlebitis, severe atherosclerosis, hypercalcemia, childhood.

Interaction with other drugs

Not compatible with tetracyclines. With simultaneous use reduces the effect of calcium channel blockers, with quinidine - it is possible to slow down intraventricular conduction and increase the toxicity of quinidine. During treatment with cardiac glycosides, parenteral use of calcium chloride is not recommended, due to increased cardiotoxicity.

Overdose

:
drug overdose calcium chloride can cause depression of cardiac activity and the appearance of tachycardia.

Storage conditions

Keep out of the reach of children at a temperature of 15-25°C. Shelf life -5 years.

Release form

Calcium chloride - solution for injection.
5 ml or 10 ml in an ampoule; 10 ampoules in a box;
5 ml or 10 ml in an ampoule; 5 ampoules in a blister; 2 blisters in a pack.

Compound:
1 ml of the drug calcium chloride contains calcium chloride 0.1 g.
Excipients: water for injections.

Additionally

calcium chloride should not be injected under the skin or into the muscles, due to its pronounced irritant and necrotizing effect. With intravenous administration of the drug, the usual reaction to it appears - a feeling of heat in the mouth, and then throughout the body.
If the drug solution gets under the skin or into the muscles, if possible, suck out calcium chloride with a syringe and inject 10 ml of sodium sulfate, 25% injection solution or 5-10 ml of magnesium sulfate, 25% injection solution at the injection site. To eliminate the resorptive effect, diphenhydramine is prescribed, with hypercalcemia - EDTA.
When prescribing the drug during pregnancy and lactation, it is necessary to weigh the expected benefit to the mother and the potential risk to the child.

main parameters

Name: CALCIUM CHLORIDE