Suprastin instructions for the use of tablets for children. Suprastin for children: instructions, indications and contraindications

Suprastin- a popular antihistamine drug that has anti-allergic, anti-edematous and antipruritic effects. It is widely used for therapy allergic conditions and treatment inflammatory diseases respiratory tract in adults and children. The drug is included in the list of vital drugs.

Suprastin is a prominent representative of the first generation antihistamines, the mechanism of application of which is aimed at blocking histamine receptors and providing an antispasmodic effect. Numerous studies that have been conducted on chloropyramine have shown that Suprastin is very effective in treating hay fever and other allergic pathologies.

Despite the advent of drugs latest generations with a limited list side effects, Suprastin is still used when an immediate effect is needed. 15 minutes pass - and the first signs of the action of an anti-allergic agent are already noticeable. However, do not forget that self-treatment can lead to undesirable results. Self appointment Suprastin can be a single dose before the doctor arrives, only in emergency. Or if there is confidence that the child really has an allergy attack and there have already been such signs before and the drug has already been prescribed.

Description of the drug Suprastin is not intended for prescribing treatment without the participation of a doctor.

Instructions for use:

How suprastin works

In the treatment of allergic reactions, drugs are used that affect the metabolism of histamine (antihistamines). The action of suprastin in allergies is primarily aimed at suppressing the activity of histamine. Suprastin blocks histamine receptors (H1), thus preventing the appearance of signs and symptoms of allergies. In addition, suprastin has a pronounced antipruritic effect.

After taking suprastin inside, the drug is quickly and completely absorbed into the blood from the intestine. Maximum concentration the drug is reached 2 hours after application. As a rule, suprastin is well distributed in the human body (penetrates the brain). Excretion of the drug is carried out through the kidneys (with kidney failure dose should be reduced).

Pharmacodynamics

Chloropyramine is a chlorinated analogue of tripelenamine (pyribenzamine) - a classic antihistamine drug belonging to the group of ethylenediamine antihistamines. Blocker of H1-histamine receptors, has an antihistamine and m-anticholinergic effect, has an antiemetic effect, moderate antispasmodic and peripheral anticholinergic activity.

Pharmacokinetics

When taken orally, it is almost completely absorbed from gastrointestinal tract(GIT). Therapeutic effect Chloropyramine develops within 15–30 minutes after ingestion, peaks within the first hour after ingestion, and lasts at least 3–6 hours. It is well distributed in the body, including the central nervous system(CNS). Intensively metabolized in the liver. It is excreted mainly by the kidneys. In children, the excretion of the drug is faster than in adult patients.

Indications suprastin

• hives;
• angioedema(Quincke's edema);
• serum sickness;
• seasonal and year-round allergic rhinitis;
• conjunctivitis;
• contact dermatitis;
• pruritus;
• acute and chronic eczema;
• atopic dermatitis;
• food and drug allergy;
• allergic reactions to insect bites.

Contraindications

• hypersensitivity to the components of the drug;
• acute attack bronchial asthma;
• newborn children (term and premature);
• pregnancy;
• lactation period.

Carefully:

• angle-closure glaucoma;
• urinary retention;
• prostatic hyperplasia;
• abnormal liver and / or kidney function;
• cardiovascular diseases;
• elderly patients.

Method of application and dosage of suprastin

Tablets are taken orally during meals, without chewing and drinking enough water.

Adults

Assign 1 tablet 3-4 times a day (75-100 mg per day).

children

The dose can be gradually increased in the absence of side effects in the patient, but maximum dose should never exceed 2 mg/kg body weight.

Special patient groups

Elderly, malnourished patients: the use of the drug Suprastin requires special care, because. in these patients, antihistamines often cause side effects (dizziness, drowsiness).

Patients with impaired liver function: a dose reduction may be required due to a decrease in the metabolism of the active component of the drug in liver diseases.

Patients with impaired renal function: it may be necessary to change the regimen of the drug and reduce the dose due to the fact that active ingredient mainly excreted through the kidneys.

How long can suprastin be taken

The course of treatment with Suprastin is prescribed by a doctor and is selected individually for each patient, depending on the course of the disease and its complexity.

The use of suprastin during pregnancy

There have been no adequate and well-controlled studies of the use of antihistamines in pregnancy. Therefore, the use of the drug in pregnant women (especially in the first trimester and in the last month of pregnancy) is possible only if the potential benefit to the mother exceeds possible risk for the fetus.

If necessary, the use of the drug during lactation should stop breastfeeding.

The use of suprastin in childhood

It can be used according to indications and in doses that take into account the age of the patient. The drug is not prescribed to newborns (including premature babies). The medicine is recommended for children from 1 month of age. The course and frequency of application directly depend on pathological process. With mild manifestations of an allergic reaction, the drug can be given to the child no more than 1 time per day. What if the allergy is complex form, then you can take the drug 3 times a day.

Parents should remember that a child may have a completely atypical reaction to the drug Suprastin in the form of hyperexcitability, anxiety and insomnia. The course of treatment of children with Suprastin can not be more than 7 days, if during this period of time the signs of allergy have not disappeared, then you need to seek help from a doctor.

Side effects

Side effects, as a rule, occur extremely rarely, are temporary, disappear after the drug is discontinued.

Other: Difficulty urinating, muscle weakness, increased internal eye pressure, photosensitivity.

If any of the above effects occur, you should stop taking the drug and consult a doctor immediately.

Overdose

Symptoms

• hallucinations;
• anxiety;
• ataxia;
• impaired coordination of movements;
• athetosis;
• convulsions.

In children early age agitation, anxiety, dry mouth, fixed dilated pupils, redness of the face, sinus tachycardia, urinary retention, fever, coma.

In adults, fever and flushing of the face are observed inconsistently, after a period of excitement, convulsions and postconvulsive depression, coma follow.

Treatment

In the period up to 12 hours after taking the drug inside, gastric lavage is necessary (it should be borne in mind that the emptying of the stomach is prevented by the anticholinergic effect of the drug). Also shown is the use activated carbon. Parameter control required blood pressure and breathing. Symptomatic therapy. resuscitation activities. The specific antidote is not known.

Interaction with other drugs

The drug should be used with caution sedatives, tranquilizers, analgesics, MAO inhibitors, tricyclic antidepressants, atropine and / or sympatholytics, as with simultaneous application the effects of these funds may be enhanced.

Interaction of suprastin with alcohol

Suprastin tends to enhance the effect ethyl alcohol on the CNS. For the duration of course therapy from any alcohol (including medicinal tinctures) should be avoided.

Special instructions for use

Each tablet contains 116 mg lactose monohydrate. This amount may cause adverse reactions in patients with lactose deficiency or rare metabolic disorders - galactosemia or glucose / galactose malabsorption syndrome.

When combined with ototoxic drugs, Suprastin may mask early signs ototoxicity.

Diseases of the liver and kidneys may require a change (reduction) in the dose of the drug, and therefore the patient should inform the doctor about the presence of

Transport and mechanisms management

The drug, especially in the initial period of treatment, can cause drowsiness, fatigue and dizziness. Therefore, in the initial period, the duration of which is determined individually, driving is prohibited. Vehicle or performing work associated with an increased risk of accidents. After that, the degree of restriction on driving vehicles and working with mechanisms, the doctor must determine for each patient individually.

Release form

Tablets 25 mg. 20 tablets in brown glass bottles with PE caps. The bottle is packed in a cardboard box along with instructions for use. medical use. Or 10 tablets in a blister. 2 blisters are packed in a cardboard box along with instructions for medical use.

In addition to the standard pack in pharmacies, there is a variety in the form of ampoules containing 20 mg of chloropyramine hydrochloride. It is sold in packs of 5 ampoules and contains, in addition to the active substance, water for injection.

Solution for intravenous and intramuscular injection it is used when it is urgent to relieve allergy symptoms - Quincke's edema, suffocation or convulsions. In such cases, the solution is administered intravenously for instant action. To use at home, you need to have skills intravenous injections children.

Storage conditions

At a temperature of 15–25 °C, out of the reach of children.

Best before date

5 years. Do not use after the date indicated on the package.

Terms of dispensing from pharmacies

Without recipe.

The price of suprastin

• tablets of 20 pcs. in a package - from 110 rubles;
• solution of 10 ampoules per pack - from 150 rubles.

Suprastin analogs

Today there is a large number of antihistamines, which help to effectively deal with allergic reactions of the body to any of the existing allergens, the most common:

• Suprastinex;
• Cetrin;
• Zyrtec;
• Loratadin-Hemofarm;
• Erius;
• Tavegil;
• Chlorpyramine-Perein;
• Disolin;
• Zodak;
• Claritin;
• Fenistil;
• Aleron.

Suprastin or tavegil

What is better to take during the allergy period - Suprastin or Tavegil? These drugs belong to the same group of drugs - antihistamines. The main indication for both Suprastin and Tavegil are allergic diseases of various nature.

But what is better - Tavegil or Suprastin? The main difference between these drugs is the manufacturer: Suprastin - domestic medicine, Tavegil - foreign. Unlike Suprastin, Tavegil is prescribed for children over the age of six.

The effectiveness of both drugs is quite high. Both drugs belong to the first generation of antiallergic drugs. The basis of Tavegil is the substance clemastine, and Suprastin is chloropyramine.

In Suprastin, a pronounced side effect is severe drowsiness. Tavegil of this side effects deprived, which distinguishes him from Suprastin. However, Tavegil has a much wider range of contraindications and side effects.

Suprastin or Cetrine

Cetrin (cetirizine hydrochloride) is a 2nd generation agent that is a highly selective H1-type histamine prescription antagonist. The drug has 2 forms of release - tablets, which are used in patients older than 6 years, and syrup, which is prescribed from 2 years of age.

Cetirizine hydrochloride is practically not biotransformed in the body, the rate of its excretion is associated with functional state kidneys. A feature of the drug is the ability to penetrate well into the skin, which makes Cetrin especially effective in skin manifestations allergies.

The drug does not have a proarrhythmic effect, which has been proven in the course of preclinical and clinical research. This means that the use of Cetrin is much less often accompanied by the development adverse reactions than the use of 1st generation products. At the same time, the degree of severity of the latter is also less than that of Suprastin.

If we talk about anti-allergic activity, then Suprastin is considered a slightly stronger remedy.

Questions and answers on the topic "Suprastin"

Question:Hello! My son (4 years old) has bronchial asthma, mild degree, at the end of May there was an exacerbation, for 10 days they drank suprastinex 10 drops once a day. Allergy symptoms are showing up again today. Is it possible to start a course of suprastinex again? At what time intervals can suprastinex be given?

Answer: Treatment with the drug can be stopped when the symptoms disappear and resumed when they appear.

Question:Hello. Today we were vaccinated (hepatitis B, poliomyelitis, diphtheria, whooping cough and tetanus), they told us to drink suprastin 1/4 before meals at home, but they didn’t tell us how many times a day to give and how long to take it either. Son is 4 months old. Do I need to give suprastin and how many times?

Answer: Hello! Usually, antihistamines are prescribed for children with manifestations of an allergic mood (diathesis, rashes, true eczema). In this case, they can be prescribed 3 days before vaccination - and with pronounced changes in the skin, they are given within 5-7 days after it. Suprastin is dosed at 1-2 mg / kg per day. If, for example, your baby weighs 7 kg, he needs 7-14 mg of suprastin per day. In 1 tablet - 25 mg. That is, with unsharply expressed allergic manifestations(and you would certainly report about pronounced ones) 1/4 tablet is enough 1 time per day.

*registered by the Ministry of Health of the Russian Federation (according to grls.rosminzdrav.ru)

Registration number:

Tradename:

International non-proprietary name:

Dosage form:

Compound:

Description

White or greyish-white, beveled disc-shaped tablets, debossed with "SUPRASTIN" on one side of the tablet and scored on the other side, odorless or almost odorless.

Pharmacotherapeutic group:

ATC Code: R06AC03

Pharmacological properties

Pharmacodynamics

Chloropyramine, a chlorinated analogue of tripelenamine (pyribenzamine), is a classic antihistamine belonging to the group of ethylenediamine antihistamines.
Blocker of H1-histamine receptors, has an antihistamine and m-anticholinergic effect, has an antiemetic effect, moderate antispasmodic and peripheral anticholinergic activity.

Pharmacokinetics

When taken orally, it is almost completely absorbed from the gastrointestinal tract (GIT).
The therapeutic effect of chlorpyramine develops within 15-30 minutes after ingestion, reaches a maximum within the first hour after ingestion and lasts at least 3-6 hours. It is well distributed in the body, including the central nervous system (CNS). Intensively metabolized in the liver. It is excreted mainly by the kidneys. In children, the excretion of the drug is faster than in adult patients.

Indications

Urticaria, angioedema (Quincke's edema), serum sickness, seasonal and perennial allergic rhinitis, conjunctivitis, contact dermatitis, pruritus, acute and chronic eczema, atopic dermatitis, food and drug allergies, allergic reactions to insect bites.- hypersensitivity to the components of the drug

Contraindications

Carefully

Angle-closure glaucoma, urinary retention, prostatic hyperplasia, abnormal liver and/or kidney function, cardiovascular disease, elderly patients.

Pregnancy and lactation

Dosage and administration:

Adults: appoint 1 tablet 3-4 times a day (75-100 mg per day).

Children:
Aged from 1 to 12 months: 1/4 tablet (6.5 mg) 2-3 times a day (in powdered form along with baby food);
Aged from 1 to 6 years: 1/4 tablet 3 times a day or 1/2 tablet 2 times a day;
Aged from 6 to 14 years: 1/2 tablet (12.5 mg) 2-3 times a day.
The dose can be gradually increased in the absence of side effects in the patient, but the maximum dose should never exceed 2 mg/kg of body weight.

Special groups patients

Elderly, debilitated patients
drugs often cause side effects (dizziness, drowsiness).

Patients with impaired liver function:
dose reduction may be required due to a decrease in the metabolism of the active component of the drug in liver diseases.

Patients with impaired renal function:
it may be necessary to change the regimen of the drug and reduce the dose due to the fact that the active ingredient is mainly excreted through the kidneys.

Side effects

From the side of the central nervous system:
drowsiness, fatigue, dizziness, nervous excitement, tremor, headache, euphoria.

From the gastrointestinal tract:
abdominal discomfort, dry mouth, nausea, vomiting, diarrhea, constipation, loss or increase in appetite, pain in the upper abdomen.

From the side of cardio-vascular system:
decrease in blood pressure, tachycardia, arrhythmia. A direct relationship of these side effects with taking the drug has not always been established.

From the hematopoietic system:
very rarely: leukopenia, agranulocytosis.

Other: difficulty urinating, muscle weakness, increased intraocular pressure, photosensitivity.

If any of the above effects occur, you should stop taking the drug and consult a doctor immediately.

Overdose

Symptoms: hallucinations, anxiety, ataxia, incoordination, athetosis, convulsions. In young children, agitation, anxiety, dry mouth, fixed dilated pupils, reddening of the face, sinus tachycardia, urinary retention, fever, coma. In adults, fever and flushing of the face are observed inconsistently, after a period of excitement, convulsions and postconvulsive depression, coma follow.

Treatment: in the period up to 12 hours after taking the drug, gastric lavage is necessary (it should be borne in mind that the anticholinergic effect of the drug prevents gastric emptying). The use of activated carbon is also shown. It is necessary to control the parameters of blood pressure and respiration. Symptomatic therapy. resuscitation activities. The specific antidote is not known.

Interaction with others medicines

The drug should be used with caution with: sedatives, tranquilizers, analgesics, MAO inhibitors, tricyclic antidepressants, atropine and / or sympatholytics, since the effects of these drugs may increase with simultaneous use.

special instructions

Each tablet contains 116 mg lactose monohydrate. This amount may cause adverse reactions in patients with lactose deficiency or rare metabolic disorders - galactosemia or glucose / galactose malabsorption syndrome. When combined with ototoxic drugs, Suprastin ® may mask early signs of ototoxicity.

Diseases of the liver and kidneys may require a change (reduction) in the dose of the drug, and therefore the patient should inform the doctor about the presence of liver or kidney disease. Taking the drug at night can increase the symptoms of reflux esophagitis. Suprastin can enhance the effect of alcohol on the central nervous system, and therefore, while taking the drug Suprastin, you should avoid drinking alcoholic beverages.

Transport and mechanisms management

The drug, especially in the initial period of treatment, can cause drowsiness, fatigue and dizziness. Therefore, in the initial period, the duration of which is determined individually, it is prohibited to drive vehicles or perform work associated with an increased risk of accidents. After that, the degree of restriction on driving vehicles and working with mechanisms, the doctor must determine for each patient individually.

Release form:

Tablets of 25 mg. 20 tablets in brown glass bottles with PE caps.
The bottle is packed in a cardboard box along with instructions for medical use. Or 10 tablets in a blister.
2 blisters are packed in a cardboard box along with instructions for medical use.
20 tablets in a blister. 1 blister is packed in a cardboard box along with instructions for medical use.

Storage conditions:

Best before date:

Conditions for dispensing from pharmacies:

Manufacturer

CJSC Pharmaceutical Plant EGIS
1106 Budapest, st. Keresturi, 30-38 HUNGARY
Representative Office of CJSC "Pharmaceutical Plant EGIS"
(Hungary) Moscow
121108, Moscow, st. Ivana Franko d. 8.

* In the case of packaging and packaging of the drug in Russia, the following is additionally indicated:

Packed, packaged:
SERDIKS LLC
Russia, 142150 Moscow region,
Podolsky district, Sofyino village, building 1/1.

From allergies, whether it's a reaction to New Product or the consequences of an insect bite, not a single child is insured. Antihistamines, such as suprastin - for children, should be in any first aid kit at home, in a car or on a hike. And when you can give suprastin and how to do it, we'll figure it out together.

Quickly and gently fights the first signs of allergies.

Is suprastin possible for children

Suprastin is tradename means, the active substance of which is chlorapyramine hydrochloride. This compound, entering the body, blocks the production of histamine, which is responsible for the characteristic manifestations of allergies: redness, swelling, itching. Don't let it develop local reaction, suprastin and other antihistamines relieve the child's condition and are recommended for the following indications:

• food allergies;
• hypersensitivity reactions with insect bites;
• angioedema;

In acute forms of urticaria, the child should immediately be given an antihistamine.

• contact dermatitis;
• contact dermatitis;
• drug allergy;
• eczema.

Pay attention to the fact that suprastin does not cure allergies!

Antiallergic drugs relieve the symptoms of a hypersensitivity reaction, but do not give systemic relief from the disease. Allergy treatment prescribed by a doctor, it is complex and includes both the removal of the allergen that affects the child and the raising of the baby's immunity.

Complex treatment of allergies can only be prescribed by the attending physician.

Suprastin can be given to children from the age of 1 month. Previously not recommended, this applies to both premature babies and babies born at term.

How to give suprastin to a child

The drug "Suprastin" is available in two forms: tablets and injections (ampoules for intravenous and intramuscular injection). Injectables are used when an allergic reaction is urgently needed., which may threaten the life of the baby (for example, with Quincke's edema). Common allergy to food product or another irritant, it is enough to remove suprastin in tablets.

The injection is done only as a last resort.

Tablets are best crushed into a fine powder, it is convenient to do this in a special mortar or two spoons. AT last case the tablet is placed in one of the spoons, and the bottom of the second tablet is covered on top and crushed until a fine powder is formed.

Mix crushed tablet into powder with baby food.

Mix this powder with liquid baby food that your child usually eats. Of course, for children up to 6 months it is breast milk. In this case, it is recommended to drink the medicine from a spoon or from a syringe, pouring a little by the baby's cheek.

Attention, keep the child in an upright position (“column”) so that he does not choke!

The cost of suprastin tablets is an average of 130 rubles for 20 pieces in a blister, injection form drugs can be purchased for 130 rubles(5 ampoules).

Additional information on suprastin

Before using suprastin, also read the following information:

• contraindication is age younger than 1 month;
• suprastin is not recommended for individual intolerance;
• the drug should not be given acute attack asthma;

With asthma, antihistamines should not be given!

• suprastin contains lactose, it can cause an undesirable effect;
• used with caution in diseases of the liver, kidneys, cardiovascular system.

There is a wide range of medications that are designed to combat allergy symptoms. These include the medication in tablets and ampoules Suprastin - instructions for use allow the use of an adult and a child. The tool has long been included in the register of vital antihistamine drugs. Suprastin has a mild effect on the body, coping with allergies "perfectly".

What is Suprastin

The antihistamine medication Suprastin is used to treat allergies. Official international generic name(INN) drugs: Chloropyramine (Chloropyramine). Pharmacological group- blocker of histamine receptors. Suprastin is sold without a prescription, this remedy is moderately priced. Before taking Suprastin for allergies, it is recommended to consult a doctor and carefully study the instructions. List of analogues of the drug in Russian cities: Tavegil, Suprostilin, Tsetrin, Suprastinex.

Compound

The main active "link" of the antiallergic drug is chloropyramine (25 mg - one tablet). Even according to the instructions, the composition of Suprastin includes the following auxiliary elements:

• stearic acid;
• gelatin;
• potato starch;
• sodium carboxymethyl starch;
• lactose monohydrate;
• talc.

Release form

An antihistamine medication can be bought at any pharmacy or ordered from an online pharmacy (the medicine comes by mail). Suprastin release form - tablets and ampoules. pills white color have no smell, they are easy to recognize by the engraving "Suprastin" (photo). This dosage form is produced in packs (10-20 tablets). Suprastin in ampoules is a colorless liquid for injection intramuscularly and intravenously. As a rule, one package contains 5 ampoules.

What helps Suprastin

The relief of a variety of allergic reactions in adults and children is an indication for the use of the drug. Before drinking Suprastin, it is recommended to study the annotation in detail and find out if the medicine will help with a specific manifestation of an allergy. The use of an antihistamine can save a person from the following problems:

1. Itching, rashes on the skin.
2. allergic rhinitis(runny nose, which occurs with a special inflammatory process nasal mucosa). Runs seasonally or all year round.
3. Appointment and use of Suprastin is an excellent chance to cope with urticaria.
4. Serum disease accompanied by chills and occurring after immunobiological injections.
5. Conjunctivitis allergic type (specific inflammation ocular conjunctiva).
6. The use of the drug Suprastin effectively eliminates Quincke's edema with a volume increase in soft tissues.
7. Removal of chronic or acute eczema with characteristic symptoms on the skin.
8. Reducing the severity of allergies provoked by the ingestion of foreign proteins through insect bites.
9. Allergic reaction varying degrees severity on food or medicines (for example, antibiotics) is also perfectly eliminated by the use of Suprastin.
10. Contact type dermatitis, which appeared due to local contact skin with different allergens.

Mechanism of action

Slowing down histamine production is the main pharmachologic effect Suprastin. Histamine is a biologically active compound. It is released into the body when cells are damaged by allergens. According to the instructions, the drug Suprastin can block histamine receptors, preventing the development allergic symptoms and eliminating discomfort (scabies, pruritus). In addition to this, the drug has sedative effect relieves spasms.

Main active substance Chloropyramine begins a healing effect on the body in 15-20 minutes. Maximum effect Suprastin appears approximately 60 minutes after ingestion and lasts 3-6 hours in a row. As a rule, the medicine "works" faster in the children's body, in adults the reaction is a little slower. The shelf life of the drug is 5 years.

Instructions for use Suprastin

In order for the elimination of allergy symptoms to be successful, the use of Suprastin must be correct. To do this, you must carefully study the instructions for using the drug. It is also worth consulting with a doctor who will draw up a treatment regimen and help you choose the right dosage of the medicine. The required dose of Suprastin depends on the severity of the signs of the disease, the age of the patient and his weight, the presence of concomitant diseases.

For kids

Doctors often prescribe Suprastin to children; even infants are allowed to use it. There is only one contraindication according to the instructions: the drug should not be given to a newborn in the first month. The tool copes well with children's allergies different types. The dosage of Suprastin for a child is prescribed exclusively by a doctor. If a small patient tolerates the effect of the drug well, then its amount increases (no more than 100 mg per day). The duration of therapy depends on the individual characteristics of the child, but, as a rule, treatment lasts about a week.

For adults

If a man or woman has allergy symptoms, then Suprastin for adults will cope with them perfectly. The duration of the treatment process is determined by the doctor, it is due to the severity of the symptoms and the patient's sensitivity to the medication. Average duration course - 7 days, if the disease has severe form the therapy continues. According to the instructions for use, Suprastin in tablets or injections has a sedative (hypnotic) effect - treatment of elderly or malnourished people should be started carefully.

How to take Suprastin

The most optimal treatment algorithm and required doses medicines, as mentioned above, are prescribed by the doctor. The dosage of Suprastin is determined by the specificity and severity of allergy symptoms, the presence of current ailments, body weight and age category sick. The following describes the features of the use of Suprastin in various dosage forms that are in the instructions.

In ampoules

If a person has severe allergic reaction acute form who needs urgent medical care, then Suprastin is used in injections. Injections are given into a vein or muscle. An adult is administered intramuscularly 1-2 ampoules per day. Dose for a child:

• from one month old up to a year - the fourth part of the ampoule (0.25 ml);
• from 1 to 6 years - half the contents of the ampoule;
• from 6 to 14 years old - an ampoule of medicine per day.

When an anaphylactic life-threatening reaction is observed, according to the instructions, the Suprastin solution is administered intravenously. This procedure is performed as slowly as possible, because a rapid infusion of the drug can provoke sharp drop blood pressure. The dose for an adult is 2 ml, the child is administered 0.5 ml. When the attack is stopped, put intramuscular injections(can be replaced with tablets).

Tablets

detailed and clear instructions Suprastin in tablets helps to find out the required dosage antihistamine medication. Children over 14 and adults are allowed to drink one pill 4 times a day. The maximum dose is 100 mg. The drug is taken in the process of eating, it is swallowed whole and washed down large quantity liquids. Child Therapy Scheme:

1. Small children from a month to a year - ¼ part three times a day. The drug can be crushed to a powder state and given to the baby with water, baby food.
2. From 1 to 6 years of age - the third part of the anti-allergic pill three times in 24 hours.
3. According to the instructions, the dosage for children from 6 to 14 years old is half a tablet three times a day.

Price

Buying an anti-allergic agent in Moscow or St. Petersburg is very simple. You can make a purchase at any pharmacy, place an order via the Internet (such pharmaceutical stores often have promotions, discounts, and there is free delivery). To find out how much Suprastin costs, below is a convenient table with the price of the drug. The cost of an antihistamine depends on the form of release of the drug, the manufacturer and the pharmacy margin.

Suprastin ( active substance- chloropyramine) is an original antiallergic drug, an antagonist of H1-histamine receptors from the group of first-generation antihistamines. Life does not stand still, as does the progress of pharmaceutical science, and for last years there are enough second-generation antihistamines. However, the relative "oldies" are by no means going to give up their positions, especially since they have a number of exclusive and useful under certain clinical setting properties (sedative and anticholinergic effects, antiserotonin activity). Although the same sedative effect of first-generation antihistamines should not be exaggerated. Over the past 10 years, a number of comparative studies have been conducted, as a result of which the estimated difference in the degree of sedation between first and second generation antihistamines is not so significant. Moreover, in some cases it was not observed at all.

Suprastin is a classic first-generation antihistamine that exhibits pronounced antihistamine and M-anticholinergic properties. The main purpose of this drug is to treat allergic diseases, including urticaria, hay fever, contact dermatitis, insect bites, etc. However, this is not an exhaustive list that limits the scope of suprastin. Publications appeared in medical periodicals about the successful use of this drug in ARVI. Unlike blockers of H1-histamine receptors of the second generation, which do not have anticholinergic activity (for example, the same phencarol or diazolin), the mechanism of action of suprastin develops in two directions: it is capable of both blocking H1-histamine receptors and exhibiting competitive antagonism against muscarinic receptors, through which stimulation of the secretion of the nasal glands and expansion blood vessels.

However, that's not all: penetrating the blood-brain barrier, suprastin interacts with the receptors of the hypothalamus and medulla oblongata, blocking the parasympathetic flow of the nasal glands and blood vessels, as well as inactivating the sneezing center. Clinically, this is manifested by a decrease in swelling of the mucous membrane and a decrease in nasal congestion and rhinorrhea, a decrease in itching, and suppression of sneezing. Thus, thanks to long period the use of suprastin in medical practice to date, sufficient information has been accumulated on this preparation allowing its use in a wide clinical range. At the same time, it remains a reliable remedy for the treatment of allergies and infectious and inflammatory diseases of the respiratory tract.

Suprastin is available in two dosage forms: tablets and injection. Tablets should be taken with food: 25 mg (1 tablet) 3-4 times a day. In children, depending on age, other dosages: 6.5 mg 2-3 times a day in the form of crushed and mixed with baby food (up to 1 year), 12.5 mg 2 times a day (up to 6 years), 12 .5 mg 2-3 times a day (up to 14 years). As for the solution, the recommended daily dose for adult patients is 1-2 ml, for children - 0.25 ml (up to 1 year), 0.5 ml (up to 6 years), 0.5 - 1 ml (up to 14 years).

Pharmacology

Antiallergic drug. Blocker of histamine H 1 receptors.

Chloropyramine hydrochloride, a chlorinated analog of tripelenamine (pyribenzamine), is a classic antihistamine belonging to the group of ethylenediamine antihistamines.

It has an antihistamine and m-anticholinergic effect, has an antiemetic effect, moderate antispasmodic and peripheral anticholinergic activity.

The therapeutic effect of chlorpyramine develops within 15-30 minutes after ingestion, reaches a maximum within the first hour after ingestion and lasts at least 3-6 hours.

Pharmacokinetics

Suction

After oral administration, chloropyramine hydrochloride is almost completely absorbed from the gastrointestinal tract.

Distribution and metabolism

It is well distributed in the body, including the central nervous system. Intensively metabolized in the liver.

breeding

It is excreted mainly by the kidneys.

Pharmacokinetics in special clinical situations

In children, the excretion of the drug is faster than in adults.

Release form

White or greyish-white, beveled disc-shaped tablets, debossed with "SUPRASTIN" on one side and a notch on the other, odorless or almost odorless.

Excipients: stearic acid, gelatin, sodium carboxymethyl starch (type A), talc, potato starch, lactose monohydrate - 116 mg.

10 pieces. - blisters (2) - packs of cardboard.
20 pcs. - blisters (1) - packs of cardboard.
20 pcs. - brown glass bottles with PE caps (1) - cardboard packs.

Dosage

Tablets

Tablets should be taken orally with meals, without chewing and drinking plenty of water.

Adults are prescribed 25 mg (1 tab.) 3-4 times / day (75-100 mg / day).

For children, the drug is prescribed in the following doses:

The dose can be gradually increased in the absence of side effects in the patient, but the maximum dose should not exceed 2 mg/kg of body weight.

Solution for i / m and / in the introduction

In / in the introduction is used only in acute severe cases under the supervision of a physician.

The dose can be carefully increased depending on the response of the patient and the observed side effects. However, the dose should never exceed 2 mg/kg body weight.

At severe course Allergy treatment should begin with a cautious slow intravenous injection, and then continue with an intramuscular injection or oral administration of the drug.

Special patient groups

Elderly, malnourished patients: the use of the drug Suprastin ® requires special care, because. in these patients, antihistamines often cause side effects (dizziness, drowsiness).

Patients with impaired liver function: a dose reduction may be required due to a decrease in the metabolism of the active component of the drug in liver diseases.

Patients with impaired renal function: it may be necessary to change the regimen of the drug and reduce the dose due to the fact that the active ingredient is mainly excreted by the kidneys.

Overdose

Symptoms: hallucinations, anxiety, ataxia, incoordination, athetosis, convulsions; in young children - agitation, anxiety, dry mouth, fixed dilated pupils, reddening of the face, sinus tachycardia, urinary retention, fever, coma; in adults - fever and redness of the face are observed intermittently, after a period of excitement, convulsions and postconvulsive depression, coma follow.

Treatment: up to 12 hours after taking the drug - gastric lavage (it should be borne in mind that the anticholinergic effect of the drug prevents gastric emptying), administration of activated charcoal, control of blood pressure and respiration parameters, symptomatic therapy, if necessary - resuscitation. The specific antidote is unknown.

Interaction

The drug should be used with caution with sedatives, tranquilizers, analgesics, MAO inhibitors, tricyclic antidepressants, atropine and / or sympatholytics, because. with the simultaneous use of the effects of these drugs may increase.

Side effects

Side effects occur, as a rule, extremely rarely, are temporary and disappear after discontinuation of the drug.

From the side of the central nervous system: drowsiness, fatigue, dizziness, nervous excitement, tremor, headache, euphoria.

From the side digestive system: abdominal discomfort, dry mouth, nausea, vomiting, diarrhea, constipation, loss or increase in appetite, epigastric pain.

From the side of the cardiovascular system: a decrease in blood pressure, tachycardia, arrhythmia (the direct relationship of these side effects with the drug has not always been established).

From the hematopoietic system: very rarely - leukopenia, agranulocytosis.

Others: difficulty urinating, muscle weakness, increased intraocular pressure, photosensitivity.

If any of the above effects occur, you should stop taking the drug and consult a doctor immediately.

Indications

• hives;
• angioedema (Quincke's edema);
• serum sickness;
• seasonal and year-round allergic rhinitis;
• conjunctivitis;
• contact dermatitis;
• skin itching;
• acute and chronic eczema;
• atopic dermatitis;
• food and drug allergies;
• allergic reactions to insect bites.

Contraindications

• acute attack of bronchial asthma;
• pregnancy;
• lactation (breastfeeding);
• newborn children (term and premature);
• hypersensitivity to the components of the drug.

With caution, the drug should be used for angle-closure glaucoma, in patients with urinary retention and prostatic hyperplasia, with impaired liver and / or kidney function, cardiovascular diseases, in elderly patients.

Application features

Use during pregnancy and lactation

There have been no adequate and well-controlled studies of the use of antihistamines in pregnancy. Therefore, the use of the drug in pregnant women (especially in the first trimester and in the last month of pregnancy) is possible only if the potential benefit to the mother outweighs the possible risk to the fetus.

If necessary, the use of the drug during lactation should stop breastfeeding.

Application for violations of liver function

With caution, the drug should be used for violations of liver function.

Patients with impaired liver function: a dose reduction may be required due to a decrease in the metabolism of the active component of the drug in liver diseases.

Application for violations of kidney function

The drug should be used with caution in case of impaired renal function.

Patients with impaired renal function: it may be necessary to change the regimen of the drug and reduce the dose due to the fact that the active ingredient is mainly excreted through the kidneys.

Use in children

The drug is contraindicated for use in newborns (including preterm infants).

special instructions

When combined with ototoxic drugs, Suprastin ® may mask early signs of ototoxicity.

Diseases of the liver and kidneys may require a change (reduction) in the dose of the drug, and therefore the patient should inform the doctor about the presence of liver or kidney disease.

Taking the drug at night can increase the symptoms of reflux esophagitis.

Suprastin ® can enhance the effect of ethanol on the central nervous system, and therefore, while taking the drug Suprastin ®, you should avoid drinking alcoholic beverages.

Each tablet contains 116 mg lactose monohydrate. This amount may cause adverse reactions in patients with lactase deficiency or rare metabolic disorders - galactosemia or glucose / galactose malabsorption syndrome.

Influence on the ability to drive vehicles and control mechanisms

The drug, especially in the initial period of treatment, can cause drowsiness, fatigue and dizziness. Therefore, in the initial period, the duration of which is determined individually, it is prohibited to drive vehicles or perform work associated with an increased risk of accidents. After that, the degree of restriction on driving vehicles and working with mechanisms, the doctor must determine for each patient individually.