Candles "genferon light" for children. Instructions for use of vaginal and rectal suppositories geneferon - composition, side effects and analogues

Genferon: instructions for use and reviews

Latin name: Genferone

ATX code: L03AB05

Active substance: interferon human recombinant alpha-2b (interferon alfa-2b) + taurine (taurine) + benzocaine (benzocaine)

Producer: CJSC "Biocad" (Russia)

Description and photo update: 03.11.2017

It is often quite difficult to choose the right drug. In order to make your choice, it is recommended that you familiarize yourself with the basic information about the properties of each medication, take into account the available side effects and contraindications. Below, drugs such as Viferon and Genferon will be analyzed.

With rectal use, interferon is absorbed into the blood, which has a systemic effect on the body: immunomodulatory and antiviral.

Let's figure out which is better - "Viferon" or "Genferon".

Antiviral suppositories "Viferon"

This tool has been produced since 1998 by Feron LLC.

Candles contain, in addition to recombinant interferon alpha-2b, vitamins C and E, which are cell membrane stabilizers and enhance the effect of interferon. The basis of the candle is cocoa butter (it can cause allergic reactions), as well as confectionery fat. The drug is produced in the form of rectal suppositories (150,000, 500,000, 1,000,000, 3,000,000 units), in the form of a gel and ointment. Candles are administered exclusively rectally. If the patient has genitourinary infections, then it is best to use Viferon in the form of a gel for injection into the uterine cervix or into the vagina.

The drug is allowed to be used from birth for the treatment of children.

Dosage

Dosage: children from birth to seven years of age are prescribed suppositories 150,000 IU, patients older than seven and adults - 500,000 IU.

As a prophylactic against influenza and SARS: one suppository once a day for ten to thirty days.

Therapeutic scheme: twice a day, one candle for five to ten days. Then a break is made for five days and, if necessary, a second course can be taken.

Which is better - "Viferon" or "Genferon"? The question is very relevant.

Antiviral suppositories "Genferon"

The drug has been produced since 2005 by JSC "Biocad" in Moscow.

It is produced in the form of suppositories intended for both rectal and vaginal use (this distinguishes them from the drug "Viferon", which is administered exclusively rectally), as well as in the form of a nasal spray. The action of a systemic nature is noted only with rectal use of the agent, since with a similar method of administration, its absorption is carried out by eighty percent. With endonasal and intravaginal application, it is characterized by local influence (in the nose or in the vagina at the site of application, on mucous membranes).

What is better for children - "Genferon" or "Viferon", you can check with your doctor.

What's in the composition?

The preparation contains recombinant interferon alpha-2b, as well as benzocaine and taurine. The latter activates the recovery processes, has an immunostimulating effect and stabilizes the membranes. Benzocaine provides local anesthesia, with intravaginal use it helps to eliminate discomfort and itching, with rectal use, the presence of this component is not important. At the heart of the candle is solid fat.

Which is better - candles "Viferon" or "Genferon light", interesting to many.

"Genferon Light"

There is also a form of release of the drug specifically for children - "Genferon Light" in the form of suppositories that contain interferon in the amount of 125,000 and 250,000 IU. It can be used from birth. If there is no light additive, then Genferon contains interferon in a higher dosage, which is intended for adult patients.

For the prevention and treatment of influenza and SARS, the drug "Genferon Light" is used rectally.

Dosage features: up to the age of seven, suppositories of 125,000 IU are shown, from seven years and adult patients - 250,000 IU.

Scheme for prevention: once a day, one candle for a period of ten to thirty days.

As a remedy: twice a day, one candle for five to ten days.

"Viferon" and "Genferon" - which is better?

These drugs are almost identical preparations, differing only in additional components in their composition and some other properties. In general, both drugs have a similar mechanism of influence, since the main active ingredient in them is recombinant human interferon alpha 2B.

These drugs can be used to treat young patients because they are completely safe. There is only one contraindication to their use - this is the presence of intolerance to any component of suppositories in a person. In practice, it turned out that the manifestation of allergic reactions occurs in rare cases. In principle, the use of the drug is quite easily tolerated by patients. "Genferon" has a slightly larger number of side effects, but they are mild, and therefore most patients simply do not notice the manifestation of negative reactions. But which is better?

Candles "Viferon" and "Genferon" differ from other antiviral agents based on interferon in that they are often used to treat acute respiratory viral infections in children. This is explained by the fact that these drugs have a low dosage, they are easy to use and well tolerated.

"Genferon" is used more often in the treatment of inflammatory processes and infections in the genitourinary tract, because it contains a local anesthetic that quickly eliminates itching and pain.

Pharmacies are often interested in what is better "Kipferon", "Viferon", "Genferon".

These drugs are very rarely used as a remedy that eliminates infections that affect digestion. Viruses in this area are recommended to be treated by other means.

"Viferon" differs from "Genferon" in that it is produced not only in the form of candles, but also in the form of an ointment and gel. Candles "Viferon" are prohibited for vaginal use by women who suffer from urinary tract infections, for these purposes an ointment or gel is usually prescribed. In turn, suppositories "Genferon" can be used not only rectally, but also vaginally.

Consider reviews about what is better for a child "Viferon" or "Genferon Light".

Among the drugs that affect the child's immune system, Genferon Light is quite popular. From what age is this medicine prescribed in candles, how exactly does it affect the immunity of babies and is it used for prevention?

Release form

One package of Genferon Light includes 5 or 10 rectal/vaginal suppositories. They have a cylindrical shape and a pointed end. The color of the candles is white, but the preparation may also have a yellow tint. Usually the structure of the drug is homogeneous, but inside there may be a recess in the form of a funnel or an air rod.

The drug is also available in liquid form, which is a nasal spray. One dose of this medicine contains 50,000 IU of the active ingredient, and the vial contains 100 doses. There is also a medicine Genferon, but it differs from Genferon Light preparations both in composition (it contains benzocaine) and in the concentration of interferon, therefore it is not used in children under 7 years of age.

Compound

The composition of candles includes two active components at once. One of them is alpha-2B interferon. One suppository can contain both 125,000 IU and 250,000 IU. The second ingredient is taurine. It, regardless of the dosage of interferon, is presented in the medicine in the amount of 5 mg per candle.

Among the excipients of the drug, you can see purified water, solid fats, citric acid and T2 emulsifier. There are also substances such as polysorbate 80, macrogol 1500 and dextran 60000 in the composition of the drug. All these components are added during manufacture to obtain suppositories weighing 0.8 g.

Operating principle

The drug refers to drugs with an immunomodulatory effect. In this case, the drug affects both locally and systemically, since more than 80% of interferon from suppositories is absorbed and enters the bloodstream. The maximum concentration of this substance in the serum is determined approximately 5 hours after the administration of the drug rectally, and its half-life occurs in 12 hours.

Let's listen to the doctor's opinion about the candles "Genferon Light".

Due to the presence of interferon in the composition, suppositories have antiviral and antibacterial effects. Their use activates some enzymes inside the cells, resulting in inhibition of virus reproduction.

The use of suppositories also affects the activity of phagocytosis and macrophages. In addition, leukocytes activated under the influence of interferon quickly eliminate pathological foci in the mucous membrane, and the production of IgA is restored.

The second component of the drug - taurine - normalizes metabolic processes and promotes tissue repair. Such a substance has the ability to stabilize membranes and antioxidant action. In addition, it supports the biological activity of interferon, due to which the therapeutic effect of suppositories is further enhanced.

Indications

Genferon Light is prescribed to a child:

• For the treatment of infections of the genitourinary system.
• As one of the drugs for the complex treatment of acute respiratory viral infections, as well as other viral or bacterial infections, such as meningitis, pneumonia, pyelonephritis, herpes.

At what age is it allowed to take?

The use of suppositories Genferon Light in children is possible from birth, even with prematurity. At the same time, for the smallest patients, the drug is prescribed at a dosage of 125,000 IU, which is often called children's. A medication with 250,000 IU, like Genferon suppositories with the same dosage, can be used from the age of 7. The spray form is not prescribed for children under 14 years of age. In addition, at the age of 14 years, vaginal administration of the drug in suppositories is not recommended.

Contraindications

The medicine should not be used if an intolerance to taurine, interferon or other ingredients of suppositories is found in a small patient. The manufacturer does not indicate other contraindications to the use of the drug, however, in case of autoimmune diseases or allergies, the use of Genferon Light requires caution and specialist advice.

Side effects

The use of Genferon Light can provoke an allergic reaction, such as burning or itching. Such negative symptoms are usually reversible, and as soon as treatment is stopped, they completely disappear within a few days.

Rarely, treatment can cause fatigue, chills, headaches, sweating, fever, and other symptoms. If they occur, the introduction of suppositories is advised to stop and consult a doctor regarding the reduction of a single dosage or replacement with another medication. If the child has a fever after the introduction of the suppository, a single dose of 250 mg of paracetamol is prescribed.

Instructions for use

According to the annotation, the suppository can be both inserted into the rectum and used vaginally. The dosage, method of administration and duration of therapy in each case, the doctor determines individually. In this case, the following schemes are most often used:

• Children under 7 years of age are usually prescribed suppositories with a dosage of 125,000 IU of interferon in one piece. This is a single dose of the drug.
• At the age of over 7 years, a drug with a higher concentration of interferon is used - 250,000 IU in 1 suppository.
• If the child has ARVI or another acute viral disease, the medicine is injected into the rectum twice a day (there should be an interval of 12 hours between applications). Treatment is prescribed for 5 days, and if the symptoms of the disease still persist, the course can be repeated after a five-day break.
• If suppositories are prescribed to a child with chronic viral pathology, as an addition to other medicines, then they are used twice a day for a 10-day course, after which they switch to a single use (the suppository is administered rectally at bedtime) every other day.
• Babies with urogenital infections Genferon Light are prescribed a course of 10 days. In this case, the candle is injected into the rectum twice a day with a pause of 12 hours.

Interaction with other drugs

Candles are often prescribed as one of the drugs for the complex treatment of the disease, so Genferon Light can be combined with antiviral, antifungal and antibacterial drugs. It is noted that in such a combination, drugs enhance the effect of each other.

Terms of sale

To buy a pack of suppositories with a concentration of interferon 250000 IU in a pharmacy, you first need to get a prescription from a doctor. But a drug with a lower dosage, containing 125,000 IU of interferon in one candle, is an over-the-counter drug. The average price of a pack of 10 suppositories of 125,000 IU of the active compound is 270-340 rubles, and a drug with a higher concentration of interferon is 380-420 rubles.




Storage conditions and shelf life

The recommended temperature conditions for storing Genferon Light candles at home is the range from +2 to +8 degrees Celsius, that is, the medication should be kept in the refrigerator. If the drug has expired (it is 2 years), then it is unacceptable to use it to treat a child.

Instructions for use

Active ingredients

Release form

suppositories

Compound

In 1 suppository: Interferon human recombinant alpha-2 1 million IU. Taurine 10 mg. Benzocaine 55 mg. purified.

Pharmacological effect

Combined drug, the action of which is due to the components that make up its composition. It has a local and systemic immunomodulatory effect. Interferon alpha-2 has antiviral, antimicrobial and immunomodulatory effects. Under the influence of interferon alpha-2, the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes, increases. The activation of leukocytes contained in all layers of the mucous membrane ensures their active participation in the elimination of primary pathological foci and the restoration of the production of secretory immunoglobulin A. Interferon alpha-2 also directly inhibits the replication and transcription of viruses, chlamydia. Taurine has membrane and hepatoprotective, antioxidant and anti-inflammatory properties, enhances tissue regeneration. Benzocaine is a local anesthetic. Reduces the permeability of cell membranes for sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, blocks the conduction of nerve impulses. Prevents the occurrence of pain impulses in the endings of sensory nerves and their conduction along the nerve fibers.

Pharmacokinetics

With vaginal or rectal application, interferon alfa-2 is absorbed through the mucous membrane, enters the surrounding tissues, into the lymphatic system, providing a systemic effect. Also, due to partial fixation on the cells of the mucous membrane, it has a local effect. A decrease in the level of serum interferon 12 hours after the administration of the drug necessitates its repeated administration.

Indications

As part of complex therapy for infectious and inflammatory diseases of the urogenital tract: - genital herpes; - chlamydia; - ureaplasmosis; - mycoplasmosis; - recurrent vaginal candidiasis; - bacterial vaginosis; - trichomoniasis; - papillomavirus infections; - bacterial vaginosis; - cervical erosion; - cervicitis; - vulvovaginitis; - bartholinitis; - adnexitis; - prostatitis; - urethritis; - balanitis; - balanoposthitis.

Contraindications

Hypersensitivity to the components of the drug.

Use during pregnancy and lactation

If it is necessary to use the drug in the II and III trimesters of pregnancy, the expected benefit to the mother and the potential risk to the fetus should be correlated.

Dosage and administration

In infectious and inflammatory diseases of the urogenital tract in women, the drug is prescribed intravaginally, 1 supp. (250 thousand or 500 thousand IU, depending on the severity of the disease) 2 times / day for 10 days. In chronic diseases, the drug is prescribed 3 times a week (every other day), 1 supp. within 1-3 months. In case of infectious and inflammatory diseases of the urogenital tract in men, the drug is prescribed rectally, 1 supp. (500 thousand-1 million IU, depending on the severity of the disease) 2 times / day for 10 days.

Side effects

Allergic reactions: skin rash, itching. These phenomena are reversible and disappear 72 hours after the dose is reduced or the drug is discontinued. When the drug is administered at a dose of 10 million IU / day, the risk of developing the following side effects increases. From the side of the central nervous system: headache. From the hematopoietic system: leukopenia, thrombocytopenia. Others : fever, increased sweating, fatigue, myalgia, loss of appetite, arthralgia.

Overdose

To date, cases of overdose of the drug Genferon have not been reported.

Interaction with other drugs

When combined with antibiotics and other antimicrobial drugs used to treat urogenital infections, the effectiveness of Genferon increases. When used simultaneously with vitamins E and C, the effect of interferon is enhanced. When used together with NSAIDs and anticholinesterase drugs, the effect of benzocaine is potentiated. When used together, antibacterial activity decreases sulfonamides (due to the action of benzocaine).

special instructions

The drug should be used with caution in patients with allergic and autoimmune diseases in the acute stage.

Genferon is a combination drug that has an immunomodulatory, antimicrobial and antiviral effect on the body. Doctors will advise how to enter it correctly.

Candles Genferon - how to enter correctly?

Components of suppositories Genferon: taurine and anestezin have anti-inflammatory, antioxidant, membrane and hepatoprotective, reparative, regenerating and anesthetic effects. Genferon is used for infectious and inflammatory diseases of the urogenital tract: chlamydia, genital herpes, prostatitis, balanitis, urethritis, adnexitis, bartholinitis, vulvovaginitis, cervicitis, cervical erosion, bacterial vaginosis, papillomavirus infections, trichomoniasis, gardnerellosis and other similar diseases. It is important to know how to administer Genferon suppositories correctly in order to achieve the maximum effect - the doctor's advice will help.

How to administer Genferon suppositories correctly - doctor's advice

The method of application and the correct doses of Genferon suppositories depend on the severity of the disease and are prescribed by the attending physician. As a rule, for women with diseases of the urogenital tract, the doctor prescribes one suppository intravaginally twice a day. The course of treatment with candles Genferon is ten days. With protracted forms of diseases, it is recommended to administer Genferon correctly three times a week every other day, in the amount of one suppository, for one to three months. In infectious and inflammatory diseases in men, Genferon is administered rectally. Doctors advise taking one suppository twice a day for ten days.

For pregnant women, the administration of Genferon suppositories is allowed after the fifth month of pregnancy, but only if the benefit of the treatment is significantly higher than the likelihood of a harmful effect on the fetus.

Doctor's advice on the correct insertion of suppositories

Like many drugs, Genferon has many side effects. Allergic reactions, sweating, joint pain, muscle and headaches, loss of appetite, fatigue, fever and chills may occur.

Candles Genferon are contraindicated in case of intolerance to the components that make up the drug, such as taurine, anesthesin, citric acid, sodium citrate, emulsifier T 2, tween 80, polyethylene oxide 1500, dextran 60000, interferon human recombinant alpha-2.

In order not to disturb yourself and your loved ones with questions about how to administer Genferon correctly, use contraception and do not have dubious intimate relationships. If you find that your regular partner is sick, then the treatment should be carried out jointly, and in this case it is also necessary to protect yourself.