properties of acetylsalicylic acid. Acetylsalicylic acid - official * instructions for use

Such a familiar and safe drug as acetylsalicylic acid can cause significant harm to health if the rules of administration specified in the instructions are not followed. It is recommended that you carefully read the sections on the use of the remedy for various conditions and read the list of contraindications.

Composition of acetylsalicylic acid

The composition of one tablet of Aspirin (acetylsalicylic acid) includes:

Mechanism of action of acetylsalicylic acid

Non-steroidal anti-inflammatory drug has analgesic, antipyretic effects.

They are associated with the suppression of cyclooxygenases of the first and second types, which regulate the synthesis of prostaglandins. The drug reduces aggregation, adhesion of platelets, the formation of blood clots by suppressing the synthesis of thromboxane in platelets.

The mechanism of action of acetylsalicylic acid is associated with the inhibition of the enzyme metabolism of arachidonic acid, a precursor of prostaglandins, which are the main cause of inflammation, fever, and pain. By reducing the amount of prostaglandins, the temperature decreases, blood vessels dilate, sweating increases. The analgesic effect is manifested in the central and peripheral systems.

With unstable angina, taking acetylsalicylic acid reduces mortality, the risk of developing myocardial infarction. It is effective in the primary prevention of diseases of the vessels, the heart, and in the secondary prevention of a heart attack. A daily dose of more than 6 g increases the prothrombin time, inhibits the synthesis of prothrombin by the liver. The drug increases the fibrinolytic property of plasma, reduces the level of vitamin K-dependent coagulation factors (albumin).

Acid disrupts the reabsorption of uric acid in the renal tubules, stimulates its excretion. Blockade of cyclooxygenase in the gastric mucosa leads to inhibition of gastroprotective prostaglandins, which can lead to ulceration of the membrane and bleeding.

From what Acetylsalicylic acid in tablets

The use of acetylsalicylic acid has the following indications:

• moderate or mild pain syndrome (headache, toothache, neuralgia, menstrual pain, migraine, arthralgia, muscle spasm, fever);
• high body temperature with a cold or infectious and inflammatory diseases (in patients older than 5 years);
• rheumatism, rheumatoid arthritis;
• primary, secondary prevention of myocardial infarction, thrombosis, embolism, ischemic cerebrovascular accident;
• the need to develop stable tolerance to non-steroidal anti-inflammatory drugs in aspirin asthma or the triad.

Method of application and dosage

In adults, the dosage of acetylsalicylic acid is prescribed individually. A single dose is 40-1000 mg, daily - 150-8000 mg with a frequency of administration 2-6 times a day. Tablets are taken before meals, washed down with a glass of water. With heart disease, the duration of admission depends on the prescription of the doctor, it can last for years.

If a dosage is missed, it is taken as soon as possible, but on the condition that the next dose is 4 hours or more later.

Otherwise, the dose is abandoned.

In cardiology, you can start and stop taking acetylsalicylic acid abruptly, at any time. For the prevention of a heart attack, use 100-300 mg every other day, with angina pectoris - every day. If you suspect a heart attack, you need to take 100-300 mg of the drug once before an attack. Then take 200-300 mg daily for a month, visit a doctor in a month.

For the prevention of thrombosis, migraine attacks, take 100-200 mg every day or 300 mg every other day. With a high risk of thromboembolism of the cerebral arteries, 300 mg are prescribed daily, gradually increasing the dosage to 1000 mg every other month. To reduce blood clotting, take 0.3 g of Aspirin every day.

Acetylsalicylic acid from temperature

With pain syndrome Acetylsalicylic acid (acidum acetylsalicylicum) is taken at 500-1000 mg, the maximum daily dose will be 3 g. A maximum of 1 g of the drug can be taken at a time, four-hour intervals are maintained between doses. Tablets are drunk after meals, washed down with water, milk, mineral alkaline water. Pain relief with aspirin should not last more than a week, fever relief - three days.

For rheumatism

Acetylsalicylic acid for rheumatism, rheumatoid arthritis, infectious-allergic myocarditis is prescribed 2-3 g for adults and 0.2 g for children for each year of life. A single dose for children up to a year will be 50 mg, 2 years - 100 mg, 3 years - 150 mg, 4 years - 200 mg. From the age of five, you can give 250 mg of Aspirin. Up to 12 years, the remedy is prescribed with caution, because there is a risk of developing Reye's syndrome (vomiting, encephalopathy, liver enlargement).

Application in cosmetology

Acetylsalicylic acid tablets are used by dermatologists in cosmetology for the treatment of inflammation, acne, acne. They cleanse the skin, remove blackheads, reduce sebum production, tighten pores, relieve swelling, eliminate acne marks, exfoliate, and maintain skin elasticity. At home, you can make masks with the drug; in cosmetology, specialized powders and pastes are used. You can apply them no more than 2-3 times a week, then protect the skin from ultraviolet radiation.

special instructions

The instructions for use say about special instructions:

1. The acid reduces the excretion of uric acid, which can lead to an acute attack of gout.
2. Long-term use of the drug requires periodic blood and stool tests.
3. Only under strict indications is it possible to take the drug once in the second trimester of pregnancy. During lactation, tablets are prohibited.
4. The remedy is prescribed with caution in diseases of the liver, kidneys, erosions, ulcers, bleeding of the gastrointestinal tract, bronchial asthma, increased bleeding.
5. As an anti-inflammatory drug, you can use no more than 5-8 g per day.
6. Salicylates are canceled 5-7 days before the operation.

During pregnancy

Due to the teratogenic potential of Aspirin, the drug should not be used in the first trimester of pregnancy. Otherwise, there is a risk of cryptorchidism (a violation of the development of the reproductive system in boys). It also increases the chance of miscarriage. The use of the drug in the third trimester can provoke pulmonary hypertension in the fetus and increase the degree of bleeding in the mother during childbirth. Aspirin is allowed in exceptional cases during the second trimester, in minimal doses and under the supervision of a physician.

In childhood

Children under 15 years of age are contraindicated in the appointment of acetylsalicylic acid to reduce body temperature in acute respiratory diseases, influenza and other febrile conditions. There is medical evidence that taking in childhood can lead to the development of hepatogenic encephalopathy (Reye's syndrome, mortality up to 35%).

drug interaction

The instructions for use indicate the drug interaction of the drug:

1. Acetylsalicylic acid increases the toxicity of Methotrexate, enhances the effects of nonsteroidal anti-inflammatory drugs, narcotic analgesics, oral hypoglycemic drugs, indirect anticoagulants, Heparin, thrombolytics, sulfonamides, platelet aggregation inhibitors, Triiodothyronine, sulfonylurea, insulin, phenytoin, valproic acid, bicarbonates. It lowers the work of uricosuric drugs, antihypertensives, diuretics, Captopril, Enalapril.
2. The combination of the drug with glucocorticosteroids, calcium channel blockers increases the risk of developing gastric bleeding, ulcerogenic action.
3. The agent increases the concentration of barbiturates, lithium preparations, Digoxin in plasma, reduces the level of Indomethacin, Piroxicam.
4. Antacids based on magnesium or aluminum hydroxide can worsen the absorption of the drug, disrupt the absorption - Griseofulvin, increase the absorption rate - caffeine.
5. The combination of the drug with gold preparations induces liver damage, with sodium alendronate - severe esophagitis, ginkgo biloba extract - spontaneous hemorrhage in the iris of the eye, Pentazocine - disruption of the kidneys.
6. Dipyridamole, carbonic anhydrase inhibitors, metoprolol increase the concentration of salicylates in the blood, which can result in intoxication.
7. Phenylbutazone reduces uricosuria caused by Aspirin.

Alcohol compatibility

The combination of acetylsalicylic acid and alcohol leads to an increase in the irritating effect on the mucous membrane of the gastrointestinal tract, which increases the risk of bleeding. At the same time, taking an Aspirin tablet 5–10 hours before the intended use of alcohol reduces the severity of the hangover syndrome.

Side effects

During treatment with acetylsalicylic acid, side effects are possible. The instruction says the following:

• vomiting, anorexia, nausea, gastric bleeding, epigastric pain, diarrhea, gastralgia, beriberi;
• anemia (lack of hemoglobin), thrombocytopenia;
• blood in the urine;
• hemorrhagic syndrome;
• hyperthermia;
• hypocoagulation;
• nephrotic syndrome;
• skin rash, allergy, bronchospasm, angioedema, aspirin triad;
• Reye's syndrome.

Overdose

With a single dose of a large dose (more than 300 mg / kg) of Aspirin, acute poisoning occurs, characterized by convulsions, stupor, coma, non-cardiogenic pulmonary edema, rapid dehydration, renal failure and shock. To reduce toxicity, activated charcoal is taken, dialysis, intravenous infusions of normal saline, dextrose, and sodium bicarbonate are prescribed.

Chronic overdose (with long-term use of elevated doses) is characterized by symptoms:

• nausea;
• vomit;
• violation of visual function;
• noise in ears;
• dizziness;
• general weakness;
• Strong headache;
• fever (poor prognostic sign).

Contraindications

The use of the drug is contraindicated in the following diseases and conditions:

• exacerbation of ulcers, erosion of the stomach;
• aspirin triad;
• gastrointestinal bleeding;
• hemophilia;
• hypoprothrombinemia;
• hemorrhagic diathesis;
• portal hypertension;
• dissecting aortic aneurysm;
• deficiency of vitamin K, glucose-6-phosphate dehydrogenase;
• renal, hepatic insufficiency;
• Reye's syndrome;
• age up to 15 years;
• first, third trimesters of pregnancy, lactation;
• intolerance to the components of the composition.

Terms of sale and storage

Acetylsalicylic acid is stored at temperatures up to 25 degrees, in a dry place out of the reach of children. Shelf life - 4 years. Sold without a prescription.

Analogues

Drugs with acetylsalicylic acid in the composition may come to replace the remedy. These are the pills:

• Asprovit;
• Aspinate;
• Aspivatrin;
• Nextrim Fast;
• fluspirin;
• Taspir;
• Aspirin.

Price

The cost of the product depends on the manufacturer, form of release, place of sale. Approximate prices in Moscow.

Probably, acetylsalicylic acid tablets have been familiar to everyone since childhood. It is very important to know the instructions for using this drug, since the remedy, despite its seeming harmlessness, has its own contraindications and side effects. And although it is common and often used, it is still necessary to know some of the nuances in the process of its application.

What is remarkable about acetylsalicylic acid tablets, the instructions for use of which we will analyze in detail in this article? Are there any restrictions on their use? How to apply this remedy depending on the disease and circumstances? We will learn about all this below.

But first, let's figure out what kind of substance it is and what is the spectrum of its action.

Main component

Acetylsalicylic acid was synthesized in German laboratories in the second half of the nineteenth century. The discovery of such an important and effective substance belongs to the pharmacological company Bayer. The same German company was the first manufacturer and distributor of a new substance that went down in history under the short name “Aspirin”. Instructions for the use of acetylsalicylic acid of that time stated that the drug, obtained from willow tree bark, has an antipyretic effect.

In our time, this tool is produced exclusively by a chemical method. In addition, thanks to numerous medical studies conducted in the twentieth century, the spectrum of action of the active substance has expanded greatly, and now Aspirin is also used for other ailments. Numerous properties of the drug are set out in detailed instructions for the use of acetylsalicylic acid for adults and children.

There was a time when the drug was considered safe and was prescribed as a prophylaxis and prevention of various pain sensations. However, now health workers are no longer so freely prescribing the drug, while they always point out to patients about its negative manifestations.

Release form

"Aspirin" is available in a dosage of 250 and 500 milligrams of the active substance. Most often, these are white-colored tablets that do not differ in a certain smell, but have a peculiar taste, without an admixture of bitterness.

The composition of the tablets

According to the instructions for use, "Acetylsalicylic acid 500 mg" consists of the active substance (0.5 grams) and additional components such as potato starch, citric acid, talc. Due to this simple composition, the drug is an inexpensive drug that does not have an unpleasant taste and has a fast-acting effect.

How it works in the body

According to scientific research, the active substance begins to act when it enters the small intestine, to a lesser extent - when it enters the stomach. A large amount of food present there can adversely affect the absorption of acetylsalicylic acid.

Due to the fact that eighty percent of the substance has a close relationship with blood plasma, the acid easily penetrates into various tissues of the body. It also actively affects the cerebrospinal, synovial and peritoneal fluids. In small quantities, acid is found in the tissues of the brain, in single - in bile, sweat, feces. Some part (rather minimal) can penetrate into breast milk.

In the joint cavity "acetyl" quickly penetrates in the presence of swelling and hyperemia, when it enters the area of ​​inflammation, its action slows down.

The substance is excreted mainly through urine.

How does it affect the body

It has already been mentioned above that “acetyl” has antipyretic properties. Its other possibilities should also include pain relief, blood thinning, and inflammation relief. What is the reason for such a result? Let's take a closer look.

The decrease in body temperature occurs due to the influence of the drug on a certain center in the brain responsible for thermoregulation. In addition, the active substance is able to influence the walls of blood vessels, expanding them, thereby increasing sweating and helping to reduce fever. This explains why acetylsalicylic acid is so effective at temperature.

The instructions for use also shed light on what is achieved by the analgesic effect. The active substance has a direct effect on the central nervous system, as well as on individual mediators located in the zone of the inflammatory process.

In some cases, "acetyl" may be prescribed by doctors to thin the blood in the vessels. This effect is achieved due to the fact that the main component acts on platelets, preventing them from sticking together and preventing the occurrence of thrombosis.

How to explain the anti-inflammatory effect of "Acetylsalicylic acid 500"? Instructions for use of the drug states that the active substance can limit access to the energy resources of healthy cells and disrupt the synthesis of prostaglandins, which are responsible for the occurrence of unpleasant symptoms at the site of the inflammatory process. Due to this, inflammation does not develop, but decreases.

For what diseases is this effective drug prescribed?

Diseases and their conditions

In rare cases, the remedy is prescribed to small patients. Most often it is prescribed for adults. Instructions for use "Acetylsalicylic acid" assures customers that the drug is able to cope with such ailments as:

• fever, fever with colds, respiratory and infectious diseases;
• pains of various etiologies (tooth, headache, muscle, neuralgia, menstruation, and so on);
• diseases of the cardiovascular system (pericarditis and others);
• ailments associated with disorders in the spine (osteochondrosis, sciatica, lumbago);
• acute thrombophlebitis (the formation of a blood clot provoked by inflammation of the venous walls);
• lung infarction (clotting of a vessel leading to the lung by a blood clot);
• pulmonary embolism;
• rheumatism, arthritis of the rheumatoid type.

A word about disease prevention

Moreover, according to the instructions for use, Acetylsalicylic Acid tablets for adults (sometimes even for children) can be prescribed as not only a treatment, but also a prevention of any disease. Most often, this is the prevention of blood clots, myocardial infarction (if there is a history of ischemic disease), as well as protection of the heart muscle in case of prolapse (in other words, dysfunction) of the mitral valve, with atrial fibrillation (when the muscle fibers of both atria are not able to work simultaneously), with various vices and so on.

First of all, it should be said that it is necessary to take “acetyl” after a meal, carefully crushing the tablet and drinking plenty of water or milk (at least a glass of liquid).

How much and when

Of course, the necessary dosage and schedule of administration is determined by the attending physician. However, according to the instructions for use for Acetylsalicylic Acid tablets, adult patients are allowed to use the remedy from forty milligrams to one gram at a time. The daily norm should not exceed five to eight grams. The number of tablets we use should be calculated in accordance with the dosage.

Most often, the course of therapy does not exceed one week, a maximum of two. If the drug is used as an antipyretic, then the duration of administration should not exceed three days.

How to take depending on the disease

And although the attending physician prescribes a specific schedule, the instructions for “acetyl” still say the following:

• With frequent pain, neuralgia and elevated body temperature, you can take the medicine three or four times a day, 0.5 or 0.25 grams, less often - one gram per dose.
• With rheumatism and heart disease, the drug can be prescribed two or three grams per day, sometimes four. The daily dose must also be divided into several doses.
• To thin thick blood and prevent thrombosis, it is recommended to use half a tablet for a fairly long period (two or even three months).
• To prevent recurrent myocardial infarction, you need to take 250 milligrams of the drug every day.
• If we are talking about various circulatory disorders, then taking “acetyl” can also be long-term. It is necessary to start with half a tablet, gradually increasing the daily dose to two tablets.

This is general information indicated in the instructions for use of "Acetylsalicylic acid". Patient reviews show that most often the attending physicians adhere to the dosage established by the manufacturer, choosing the most effective and efficient method of treatment with this inexpensive but effective remedy. And although the drug does not work miracles, it is still able to provide the necessary assistance in the process of outpatient treatment of the serious diseases listed above.

But how to take "Acetylsalicylic acid" for children? The instruction manual answers this question as well.

Treatment of young patients

In short, the daily rate of the drug should not exceed one hundred milligrams for two-year-old babies, 150 milligrams for three-year-olds, two hundred milligrams for four-year-olds. For children from five to twelve years old, “acetyl” is prescribed no more than 250-300 milligrams. The indicated dose is recommended to be divided into several doses (three or four times a day). All this is indicated in the instructions for use.

How else can help, according to the instructions for use, tablets "Acetylsalicylic acid"? For children, the drug is prescribed in the treatment of serious diseases. With pain and fever, the drug is prescribed to children from one hundred to three hundred milligrams per day (depending on age). If we are talking about diseases of the heart, joints and polyarthritis, then in 24 hours a child can take from 200 to 250 milligrams.

You should know that when acetylsalicylic acid is used by newborns, the active substance displaces bilirubin, thereby provoking. In addition, the process of removing “acetyl” in babies takes much longer than in adults. If an adult patient needs only two or three hours to completely remove the acid from the body (at a minimum dose), then this process will take five or even six hours for a child.

As you can see, the drug has both certain advantages and disadvantages. Let's talk about the latter in more detail.

More about side effects

Let's face it, there are quite a few unpleasant manifestations, but they occur extremely rarely.

From the organs of the gastrointestinal tract, disorders in the form of vomiting, nausea, and abdominal pain are possible.

Less commonly, erosions or ulcers in the stomach, bleeding may occur.

The central nervous system of a person can also react unpredictably to the use of a seemingly harmless "acetyl". On this side, you may be disturbed by dizziness and headaches, tinnitus, visual impairment, less often - aseptic meningitis.

Due to prolonged use of the drug, pathological changes in the functioning of the kidneys may be observed.

Acetylsalicylic acid can also cause allergic reactions in the form of a skin rash, bronchial spasm, angioedema, and so on.

In rare cases, but still, anemia, hemorrhagic syndrome, increased heart failure with prolonged use of the drug can be diagnosed.

What about contraindications?

Naturally, especially considering all of the above, the Acetylsalicylic Acid tablets have their own contraindications. First of all, this is the presence of a history of peptic ulcer (especially if it is in the acute phase), bleeding of the digestive tract, hemophilia, aortic aneurysms, kidney or liver failure, and much more.

With extreme caution, it is necessary to prescribe the drug to patients suffering from various liver and kidney diseases, bronchial asthma, decompensated chronic heart failure, etc.

Long-term use of "Acetylsalicylic acid" should also be avoided in patients with gout (as the drug may interfere with the excretion of uric acid from the body), as well as those who have a history of healed ulcers.

Often, the remedy is not prescribed during planned preparation for operations and in the postoperative period, since the active substance can provoke increased hematopoiesis.

Can expectant and nursing mothers take it?

This question is very important, as many people still think that "acetyl" is a harmless and harmless pain reliever or antipyretic.

According to the recommendations of experts, the drug is not prescribed during pregnancy and lactation. In the first and third trimester, it is especially contraindicated, as it can cause pathologies in the development of the fetus and premature birth.

As mentioned above, acetylsalicylic acid is able to penetrate into breast milk, thereby having a negative effect on the baby, causing him to develop bleeding.

Interaction with other drugs

Using "Acetylsalicylic acid", it is important to know that its simultaneous use with magnesium and aluminum hydroxide preparations reduces the absorption of the substance itself.

Moreover, the drug can reduce the effect of some diuretics and uricosuric drugs.

It has been established that caffeine can enhance the effect of “acetyl”.

You can learn more about the interaction of the drug with other drugs at the appointment with your doctor.

"Acetyl" and alcohol

It is believed that “Acetylsalicylic acid” helps a lot with a hangover. Instructions for use indicate this feature of the drug. Since the active substance has a blood-thinning effect, it can reduce the absorption of alcohol into the blood, while improving the well-being and general condition of a person.

How to take the drug to achieve a positive result? It should be mentioned here that the use of acetylsalicylic acid together with alcoholic beverages can lead to the development of erosions and ulcers of the digestive tract, cause internal bleeding. Therefore, experts recommend taking "acetyl" two hours before the planned feast (and this is the minimum) and six hours after drinking alcohol. A single dose of the drug should not exceed five hundred milligrams (that is, one or two tablets, depending on the dosage).

Drugs with a similar spectrum of action

What can be said about the analogues of "Acetylsalicylic acid"? The instructions for use indicate what pharmacological capabilities the active substance has. What drugs have a similar sphere of influence?

First of all, it is:

• "Aspirin Cardio", which is a coated tablet;
• "Acetylsalicylic acid MS". Instructions for use of this tool are identical to the annotations to the drug discussed in the article.
• "Acetylsalicylic acid";
• "Anopyrin";
• "Reocard";
• "Kolfarit";
• "Zorex morning";
• "Acecardol";
• "Trombopol" and so on.

- a medicine with anti-inflammatory, antipyretic action, first aid for various diseases. It is also used to prevent the occurrence of serious pathologies; the medicine has also been used in home cosmetology.

Acetylsalicylic acid is used in various diseases

Is acetylsalicylic acid Aspirin or Analgin?

Aspirin is the patented name for Acetylsalicylic acid, the salicylic ester of acetic acid. It has a pronounced antipyretic effect, helps to cope with inflammatory processes, the analgesic effect is not very pronounced.

Analgin contains metamizole sodium, helps with various manifestations of pain syndrome of varying degrees of intensity.

Packaging of aspirin tablets

Recent studies have shown that with daily use of Aspirin for 5 years, the number of deaths from cancer of the stomach and intestines decreased by almost 50%.

Release form Acetylsalicylic acid

Acetylsalicylic acid (ASA), the Latin name is Acidum acetylsalicylicum, is produced in the form of tablets with various dosages.

Release form:

• tablets containing ASA 250 and 500 mg, packed in blisters of 10 pieces;
• film-coated tablets with an active substance content of 325 mg - in glass containers of 100 pills;
• tablets of 0.1 g in blisters;
• Aspirin C - effervescent tablets, containing 400 mg of ASA and 240 mg of ascorbic acid, packed in strips of 2 tablets, 5 strips in a cardboard box.

Packaging of Aspirin C tablets

Aspirin refers to over-the-counter drugs, the shelf life is 4 years, it must be stored in a dry, darkened room at a temperature of no more than 25 degrees.

Price and analogues

How much does acetylsalicylic acid cost? Ordinary tablets - 20-25 rubles. for 20 pieces, effervescent - 220-240 rubles, Aspirin-cardio - 230-250 rubles.

ASA is part of many cardiological, analgesic, antipyretic drugs. If there are contraindications for taking Aspirin, you can choose an analogue with a similar therapeutic effect.

Acetylsalicylic acid analogues

Acetylsalicylic acid indications

Aspirin belongs to the group of non-steroidal anti-inflammatory drugs, it is prescribed to reduce temperature, eliminate foci of inflammation and pain of mild to moderate intensity.

What does acetylsalicylic acid help with?

• fever and fever against the background of infectious, respiratory and viral diseases;
• arthritis, rheumatism, arthrosis;
• neuralgia, cephalgia, myalgia, especially effectively helps with headache, which is caused by increased intracranial pressure
• toothache;
• withdrawal syndrome;
• some lesions of the heart muscle of an inflammatory nature.

Acetylsalicylic acid helps with toothache

Aspirin helps with angina, heart attack, ischemia, thrombophlebitis. It is also prescribed to prevent shunt occlusion during coronary anastomosis.

pharmachologic effect

The drug purposefully affects the thermoregulation center, which allows you to quickly reduce the temperature in case of colds and infectious diseases. ASA inhibits the production of thromboxane in platelets, which allows it to be used to reduce blood clotting, prevent the appearance of blood clots, the development of heart attacks, and strokes.

Aspirin is almost completely absorbed in the body, the therapeutic effect occurs within 25 minutes after taking the drug. The process of drug metabolism occurs in the liver, excreted by the kidneys.

The rate of excretion of Aspirin is affected by the acid-base level of urine. If there are more alkaline elements in urine, then the process is accelerated, when it is acidified, it decreases.

Instructions for use Acetylsalicylic acid

1. Ordinary ASA tablets should be crushed before use, washed down with a sufficient amount of liquid, at least 250 ml.
2. Effervescent tablets should be dissolved in 200 ml of warm water, drink the medicine immediately after preparation, if the acidity of the gastric juice is increased, then you need to additionally drink a solution of 120-200 ml of water.
3. Pills in the shell do not need to be chewed, swallowed whole, washed down with 250 ml of water.

It is better to grind ASA tablets before use.

The description states that Aspirin is addictive, so the withdrawal of the drug is carried out gradually, the dosage is reduced over 7-14 days.

Should acetylsalicylic acid be taken before or after meals? All preparations containing ASA should be taken immediately after meals. It is better to drink it with milk, alkaline medicinal waters.

Raises or lowers blood pressure

The action of ASA does not apply to arterial parameters, the drug can be taken by hypotensive and hypertensive patients. But in the course of research, it was found that with daily intake of Aspirin 100 mg immediately before bedtime, the condition of patients even with chronic forms of hypertension improves significantly. It is necessary to drink the medicine in courses of 4-6 weeks.

Acetylsalicylic acid can be used for pressure problems

For the treatment of thrombosis and embolism, Acetylsalicylic acid is taken 0.5 g every 8-12 hours. To thin the blood, the drug can be taken up to six months at a dose of 0.15-0.25 g daily - the medicine does not change the physical viscosity of the blood, but only prevents platelets from sticking together.

It is necessary to take ASA only in the presence of cardiovascular pathologies, against which blood clots can form. You can not drink medicine for preventive purposes.

With myocardial infarction

With a severe attack of angina pectoris, which cannot be stopped with Nitroglycerin, severe pain in the region of the heart, 325-500 mg of ASA should be urgently taken, the drug is most effective at the first manifestations of a heart attack - it helps prevent blood clots, cerebrovascular accident.

After a heart attack, you need to take 75 mg of ASA every evening. The minimum course duration is 4-5 weeks.

Acetylsalicylic acid helps in the early stages of myocardial infarction

To reduce the risk of developing a pre-infarction state, patients with angina pectoris are prescribed 75-300 mg / day of cardiac Aspirin - Asafen, Cardiomagnyl. The dosage and duration of the course depends on the functional class of the pathology.

How to take for a headache

ASA stop moderate and weak manifestation of cephalalgia, the medicine should be taken if the headache is associated with migraine, colds, inflammation in the nasopharynx, increased intracranial pressure, hangover.

Acetylsalicylic acid helps relieve headaches

The daily dose depends on the form and severity of the disease, the weight and age of the person, the presence of chronic diseases, but you can drink no more than 3 g of Aspirin per day, a single dosage is 40 mg–1 g.

Application for fever and colds

ASA quickly helps with elevated temperature, eliminates bone ache, cephalalgia, promotes intense sweating. A single dose is 0.25-1 g, the medicine should be taken every 4-6 hours. The last dose of the drug should be just before bedtime. Duration of therapy - no more than 14 days.

Acetylsalicylic acid is good for colds

With angina

Aspirin will help reduce the temperature, eliminate migraines with sore throat - you need to drink 0.5–1 g of the remedy 4 times a day. With the help of the drug, you can permanently get rid of discomfort in the throat. Dissolve 500 mg of ASA in 250 ml of warm water - gargle with the mixture every 6 hours.

To get rid of an unpleasant sensation in the mouth with angina, it is recommended to use Aspirin

Hangover

ASA helps to quickly eliminate the signs of withdrawal syndrome, it is better to take effervescent Aspirin.

After taking the medicine, the vessels expand, the pain syndrome disappears, the work of the kidneys improves, the remedy has a slight diuretic effect, which helps the body get rid of the toxic decomposition products of alcohol.

To get rid of a hangover, you need to take 2 effervescent tablets, but not earlier than 6 hours after drinking alcohol - improvement is observed within an hour. If necessary, another dose can be drunk after 6 hours.

Aspirin quickly eliminates the symptoms of a hangover

Many drink Aspirin to prevent the appearance of signs of alcohol intoxication - this should be done a day before the feast, take 0.5 g of ASA.

How to use for toothache

Acetylsalicylic acid disrupts the production of substances that cause fever and inflammation, reduces the sensitivity of the nerve roots, so it is often prescribed to relieve minor toothache. You need to take the drug at 500-100 mg twice a day, but not more than 2 thousand mg per day.

Because aspirin thins the blood, it should not be taken before or after a tooth extraction.

Acetylsalicylic acid relieves toothache

Acne masks

Masks with ASA help get rid of acne, puffiness, inflammation on the face - such home remedies have a whitening effect, gently eliminate dead cells, while not affecting healthy tissues. Cleansing procedures should not be carried out in the presence of scratches, excessively dry skin.

Effective aspirin masks:

1. To prepare a simple but effective mask for oily skin, you need 5 crushed Aspirin tablets, a little water to make a thick slurry. Apply the mixture to problem areas, rinse after 30 minutes.
2. Combine 10 ml of honey and 5 ml of water or jojoba oil, if the skin is dry, warm it up in a steam bath. Grind into powder 3 ASA tablets, you can take with any dosage, but not effervescent, add to the honey mixture. Steam the skin, apply the mixture, leave for 20 minutes.
3. A mask of 4 tablets of acetylsalicylic acid, 30 g of white clay and 10 g of crushed oatmeal will help get rid of blackheads and blackheads. Mix the components, add a little water to get a not very liquid mass. Apply to the skin with massage movements, remove after 20 minutes.

Aspirin mask will help improve skin condition

The effect after cleansing with Aspirin will be noticeable after 3-4 hours, masks can be used no more than twice a week. The course consists of 8-10 sessions.

Application of Aspirin for hair

ASA helps to strengthen hair, get rid of dandruff or seborrhea. Tablets can be added directly to the shampoo, or various masks can be prepared with them - with regular use, the hair becomes voluminous, the strands acquire radiance and strength, grow faster, skin itching disappears, and the sebaceous glands normalize.

For active growth and noticeable volume, you need to add acetylsalicylic acid to a portion of shampoo - 2 tablets per 10 ml. Apply the mixture on the strands, leave for 5 minutes, rinse with warm water. The procedure can be carried out once every 7 days.

Adding aspirin to shampoo will help improve hair

To eliminate dandruff, dissolve 5 tablets of Aspirin in 100 ml of water, add 30 ml of honey and aloe juice. Spread the mass evenly on the skin and root area, leave for 25 minutes.

Acetylsalicylic acid for children

Children under 15 years of age should not be given Aspirin, especially with viral infections - this often leads to the development of Reye's syndrome, a severe pathology that is accompanied by toxic damage to brain tissues, liver and kidney failure, and death.

With toothache, cephalalgia, adolescents can drink 250 mg of ASA twice a day, but more than 750 mg per day. The duration of therapy is not more than a week.

During pregnancy and lactation

Pregnant and lactating women should not take ASA-based drugs. In the early stages, the drug can provoke a miscarriage, it has a teratogenic effect - a child can be born with heart and kidney pathologies.

In the III trimester, the use of ASA can cause placental abruption, postmaturity or premature delivery, severe bleeding.

Do not take aspirin while breastfeeding

125 mg of ASA once a day can be taken in the II trimester as prescribed by a doctor - experts prescribe a medicine for increased blood clotting, varicose veins, late toxicosis, and rheumatic diseases.

Acetylsalicylic acid compatibility

Before starting treatment with Aspirin, it is necessary to carefully study the annotation, which indicates all the features of the simultaneous administration of the drug with other drugs, compatibility with alcoholic beverages.

With other drugs

ASA enhances the toxic effects on the body of barbiturates, valproic acid. Aspirin should not be taken during treatment with methotrexate if the weekly dose of the anticancer drug is more than 15 mg.

Methotrexate and Aspirin are incompatible

With the joint intake of Acetylsalicylic acid with Digoxin, narcotic painkillers, sulfonamides, hypoglycemic drugs, the therapeutic effect of drugs is enhanced. Aspirin reduces the effectiveness of diuretics, blood pressure lowering drugs, and the treatment of gout. With simultaneous use with thrombolytics, anticoagulants, the risk of bleeding increases. Glucocorticosteroids increase the negative impact of ASA on the mucous membranes of the digestive system.

With alcohol

ASA is strictly forbidden to be taken simultaneously with alcoholic beverages, drugs that contain ethanol. If this rule is not observed, irreversible changes in the liver cells, severe bleeding can begin, the likelihood of ulcers and erosions on the mucous membranes of the digestive column is high.

Do not take aspirin with alcohol

Contraindications and side effects

Taking ASA negatively affects the functioning of the digestive system, since the drug has an irritating effect on the gastric mucosa. The most common negative manifestations are nausea, cramping abdominal pain, upset stool, and allergic reactions. Sometimes patients are diagnosed with anorexia, kidney or liver failure, erosions and ulcers of the digestive tract, and the level of platelets in the blood decreases.

With long-term treatment with Aspirin, vision and hearing may temporarily deteriorate, migraine attacks and dizziness are common. Some patients experience reduced blood clotting, which can cause severe bleeding.

Contraindications:

• aspirin asthma;
• exacerbation of diseases of the digestive system, in which erosive and ulcerative lesions are observed;
• internal bleeding, hemophilia and other pathologies of blood clotting;
• vitamin K deficiency;
• increased blood pressure in the portal vein;
• aortic dissection;
• gout, gouty arthritis.

Do not take aspirin for asthma

During treatment with Aspirin, it is necessary to include in the diet foods that neutralize the negative effect of acid on the stomach - egg whites, sweet juices, meat, white flour bread, hard cheeses, marinated vegetables.

What foods contain acetyl?

Salicylates are found in various products, they have all the qualities of synthetic ASA, but at the same time they have a minimum number of contraindications and adverse reactions. Most salicylic acid, from 45 to 218 mg / 100 g, is found in spices - curry, paprika, thyme, saffron, turmeric, cumin and rosemary.

Foods High in Salicylic Acid (mg/100g)

Meat and fish do not contain salicylic acid, so they must be consumed with spices, but seasonings should be added in reasonable amounts, taking into account the state of health.

- an affordable medicine that is successfully used in cosmetology and conservation. Aspirin helps to cope with pain, inflammation, quickly lowers the temperature, prevents the development of serious cardiovascular diseases, as it thins the blood.

Instruction

Acetylsalicylic acid has analgesic, antipyretic and anti-inflammatory properties, so it can be used for migraine, rheumatism, neuralgia and fever. In addition, the drug is on platelets, and therefore is prescribed for the prevention of embolism and thrombosis. Acetylsalicylic acid is also indicated for the treatment and prevention of cardiovascular diseases such as heart attack, cerebrovascular accident, etc.

To reduce fever or reduce pain, take one tablet (500 mg) of acetylsalicylic acid. As a rule, improvement occurs within half an hour. Re-use of the drug is possible no earlier than after 4-6 hours, and the total daily dose cannot exceed 3 g.

For rheumatism, rheumatoid arthritis and infectious-allergic myocarditis, take 2 (500 mg each) acetylsalicylic acid 2-3 times a day. Drink plenty of fluids to avoid gastrointestinal side effects.

For the prevention of myocardial infarction (if there is a predisposition to an already transferred disease), drink 150-300 mg of acetylsalicylic acid daily. Duration of therapy in this case by a doctor, often lifelong continuous use of the drug is required.

Drink acetylsalicylic acid just after eating. Taking the medicine on an empty stomach can provoke the occurrence of peptic ulcer of the duodenum and stomach.

note

Refrain from drinking alcohol during treatment.

Do not use acetylsalicylic acid on a child under 15 years of age.

Sources:

• acetylsalicylic acid on temperature

Acetylsalicylic acid, better known as aspirin, is one of the most popular drugs in the world. For many decades of using aspirin in medical practice, the mechanism of action that it has on the body has been well studied, and its clinical effectiveness has been repeatedly proven. Today, acetylsalicylic acid is included in the WHO list of essential medicines and in the list of vital and essential medicines in Russia.

Acetylsalicylic acid was invented by the Alsatian chemist Charles Frederic Gerard in 1853. However, its first samples suitable for treating people were obtained only in 1897. These samples were synthesized by the German chemist Felix Hofmann in the laboratory of the pharmaceutical companies Bayer, who registered the new one under the trademark "Aspirin". The first aspirin in powder form went on sale in 1899, and in 1904 acetylsalicylic acid began to be produced in the form of tablets.

Currently, acetylsalicylic acid is produced under various trademarks: Upsarin Upsa, Aspirin Cardio, Nextrim Fast, Cardiopyrin, ASK-cardio, Taspir, Ascopirin, Therapin, Aspirin ”, “Fluspirin”, “Aspikor”, etc. Acetylsalicylic acid is also part of many popular combined painkillers, including Citramon-P, Askofen-P, Excedrin, Cofitsil-Plus, Citrapak , Citramarine, etc.

Pharmacological properties of acetylsalicylic acid

Initially, aspirin was used only as. After some time, it turned out that acetylsalicylic acid also has an analgesic and anti-inflammatory effect. Another important property of aspirin is its ability to thin the blood, which is used when there is a danger of occurrence.

Indications for taking acetylsalicylic acid are mild and moderate pain syndrome of various origins (headache, toothache, neuralgia, muscle pain, sore throat, painful, etc.); fever caused by infectious and inflammatory diseases; prevention of thrombosis, embolism, myocardial infarction and ischemic stroke.

Dosage of acetylsalicylic acid

Aspirin is intended for treatment and those who have reached 15 years of age. A single dose of acetylsalicylic acid is 500 mg, the maximum single dose is 1 g. You can drink no more than 3 g of aspirin per day. The interval between taking the tablets should be at least 4 hours.

Side effects of acetylsalicylic acid

Most often, aspirin is associated with the irritant effect that it has on. Therefore, taking acetylsalicylic acid can cause nausea, vomiting, diarrhea, and stomach bleeding. With aspirin, damage to the nervous system is possible, manifested by impaired coordination of movements, convulsions and clouding of consciousness. In severe cases, acetylsalicylic acid can cause toxic damage to the liver and kidneys. In addition, severe allergic reactions are possible, up to anaphylactic shock.

Acetylsalicylic acid is used as an antipyretic, anti-inflammatory and vasodilator. There are about 50 brands of drugs based on this substance. Aspirin is its pharmacy name. The annual consumption of medicines containing acetylsalicylic acid exceeds 40 billion tablets.

Instruction

Acetylsalicylic acid inhibits the action of enzymes responsible for the synthesis of inflammatory mediators - prostaglandins. As a result, the inflammatory response in the body is reduced. Aspirin is widely used in the treatment of rheumatic diseases, toothache and headache, migraine, neuralgia and some other pathological conditions accompanied by inflammation, pain and high fever.

Aspirin has an effect on, reduces the likelihood of blood clots. Due to

Aspirin is a widely used drug from the group of non-steroidal anti-inflammatory drugs (NSAIDs), which has analgesic, antipyretic, antiplatelet and weak anti-inflammatory effects. Aspirin is used to normalize elevated body temperature, relieve pain syndrome of various localization and origin (for example, headache, toothache, joint, menstrual pain, neuralgia, etc.), as well as an anti-inflammatory agent for chronic diseases with a sluggish inflammatory process (for example , rheumatism, arthritis, myocarditis, myositis, etc.). Separately, it is worth canceling the use of Aspirin in low dosages (2-5 times lower than the dosage for relieving pain and lowering temperature) in order to prevent thrombosis and embolism at a high risk of heart attacks, strokes, etc.

Varieties, names and forms of release of Aspirin

So, Aspirin is available in two dosage forms:
1. Tablets for oral administration;
2. Effervescent tablets for dissolution in water.

Effervescent tablets are produced under three commercial names - "Aspirin 1000", "Aspirin Express" and "Aspirin C", and are used to relieve pain. Aspirin effervescent tablets are currently available in two versions - containing only acetylsalicylic acid or acetylsalicylic acid + vitamin C. Accordingly, the drug with vitamin C is called "Aspirin C", and without it - just "Aspirin 1000" and "Aspirin Express".

Tablets for oral administration are available in two varieties - for the relief of pain, fever and for long-term use in order to prevent thrombosis. Tablets for the relief of pain and fever are called ordinary Aspirin, and tablets for the prevention of thrombosis are called Aspirin Cardio.

Compound

• Effervescent tablets Aspirin 1000 and Aspirin Express - 500 mg of acetylsalicylic acid;
• Effervescent tablets Aspirin C - 400 mg of acetylsalicylic acid and 240 mg of vitamin C;
• Tablets for oral administration Aspirin - 500 mg;
• Aspirin Cardio tablets - 100 mg and 300 mg.

• Effervescent tablets Aspirin 1000, Aspirin Express and Aspirin C-sodium citrate, sodium carbonate, sodium bicarbonate, citric acid;
• Tablets for oral administration Aspirin - microcrystalline cellulose, corn starch;
• Aspirin Cardio tablets - cellulose, corn starch, methacrylic acid and ethyl acrylate copolymer 1: 1, polysorbate, sodium lauryl sulfate, talc, triethyl citrate.

Aspirin - prescription

In the recipe after the letters "Rp." the form of release of the drug is indicated (in this case, tablets - Tab.) and its name in quotation marks. After the name, the dosage is indicated in mg or g. After the letters "D.t.d." the number of tablets that the pharmacist must give to the person upon presentation of this prescription is indicated. After the letter "S" indicates how to take the drug.

Therapeutic action

• analgesic action;
• Antipyretic action;
• Anti-inflammatory action;
• Antiplatelet action.

At low doses, Aspirin is able to reduce blood clotting and associated thrombosis, providing an antiplatelet effect. This effect is achieved by suppressing the production of thromboxane A2, a substance that causes platelets to adhere to each other.

In principle, even at higher dosages, Aspirin also has an antiplatelet effect, but in these cases, in addition to it, the drug also has an analgesic, anti-inflammatory and antipyretic effect, which turns out to be side and unnecessary if only suppression of thrombus formation is necessary.

Therefore, to achieve an isolated antiplatelet effect, Aspirin must be taken in small doses, 100-300 mg per day. And to lower the temperature, relieve pain and reduce the inflammatory process, Aspirin is taken in higher dosages, 300-1000 mg per day.

Indications for use

Aspirin tablets effervescent and for oral administration - indications for use

• Headache;
• menstrual pain;
• neuralgia;
• Lumbago, etc.

Aspirin effervescent tablets are indicated for use only in the treatment of headache or migraine attacks.

It should be remembered that effervescent and regular Aspirin tablets can only stop the symptoms, but not cure the disease. Therefore, they can be used to normalize the condition in parallel with drugs, the action of which is aimed at curing the disease.

Aspirin Cardio - indications for use

• Primary prevention of myocardial infarction in people at high risk of developing it (for example, with diabetes mellitus, hypertension, high blood cholesterol, obesity, smoking, old age over 65 years);
• Prevention of recurrent myocardial infarction;
• Prevention of strokes;
• Prevention of periodic disorders of cerebral circulation;
• Prevention of thromboembolism after surgical interventions on blood vessels (for example, coronary artery bypass grafting, arteriovenous bypass grafting, angioplasty, stenting and carotid endarterectomy);
• Prevention of deep vein thrombosis;
• Prevention of thromboembolism of the pulmonary artery and its branches;
• Prevention of thrombosis and thromboembolism during prolonged immobility;
• Unstable and stable angina;
• Non-atherosclerotic lesions of the coronary arteries (Kawasaki disease);
• Aortoarteritis (Takayasu's disease).

Instructions for use

Aspirin tablets for oral administration - instructions for use

Aspirin tablets should be taken orally after meals with plenty of water (minimum 200 ml). The tablet can be swallowed whole, divided into parts or chewed. Drinking Aspirin before meals is not recommended, as this can provoke discomfort and side effects from the digestive tract.

For pain of moderate and low intensity or elevated body temperature, Aspirin is recommended to be taken 500-100 mg (1-2 tablets) 2-3 times a day. The maximum allowable single dose is 1000 mg (2 tablets), and the daily dose is 3000 mg (6 tablets). For elderly people over 65 years of age, the maximum allowable daily dosage of Aspirin is 2000 mg (4 tablets). Between two consecutive doses of tablets, a break of at least 4 hours must be observed.

The duration of the course of using Aspirin for pain relief is a maximum of one week, and for lowering the temperature - three days. Aspirin cannot be used longer than the indicated periods, since in this case the drug masks the symptoms of the disease and, thus, does not allow it to be diagnosed in a timely manner and begin the necessary treatment.

Aspirin effervescent tablets - instructions for use

Effervescent tablets are allowed to be taken regardless of food, since they contain substances that protect the gastric mucosa from the negative effects of acetylsalicylic acid.

If a person has a deficiency of glucose-6-phosphate dehydrogenase, taking Aspirin can provoke hemolytic anemia. Therefore, in the presence of this pathology, care must be taken when taking Aspirin, avoiding its use in large doses, at temperature or acute infectious diseases.

The use of several painkillers in combination with Aspirin over a long period of time can provoke the development of kidney disease. In addition, aspirin can provoke gout attacks, because it reduces the rate of excretion of uric acid from the body.

With prolonged use for headaches, the development of the "addictive headache" syndrome is possible, when symptoms appear immediately after Aspirin is discontinued.

With prolonged use of Aspirin, it is necessary to periodically take a general blood test, fecal occult blood and monitor liver function.

Influence on the ability to control mechanisms

Overdose

For mild and moderate overdose of Aspirin, the following manifestations are characteristic:

• Hearing impairment;
• Increased sweating;
• Headache;
• confusion;
• Rapid breathing.

A severe overdose of Aspirin is manifested by the following symptoms:

• Very high body temperature;
• respiratory depression;
• Pulmonary edema;
• Drop in blood pressure;
• Depression of the work of the heart;
• Violation of water and electrolyte balance;
• Violation of the kidneys up to insufficiency;
• Increase or decrease in blood glucose levels;
• ketoacidosis;
• Noise in ears;
• gastrointestinal bleeding;
• Violation of blood clotting from prolongation of bleeding time to the complete absence of thrombus formation;
• encephalopathy;
• CNS depression (drowsiness, confusion, coma and convulsions).

Interaction with other drugs

• Heparin and indirect anticoagulants (for example, Warfarin, Thrombostop, etc.);
• Thrombolytics (drugs that dissolve blood clots), anticoagulants (drugs to reduce blood clotting) and antiplatelet agents (drugs that prevent blood clots by preventing platelets from sticking together);
• Selective serotonin reuptake inhibitors (for example, Fluoxetine, Sertraline, Paroxetine, Citalopram, Escitalopram, etc.);
• Digoxin;
• Drugs to lower blood glucose levels (hypoglycemic agents) for oral administration;
• Valproic acid;
• Drugs from the NSAID group (Ibuprofen, Nimesulide, Diclofenac, Ketonal, Indomethacin, etc.);
• Ethanol.

It should be remembered that when taking Aspirin with anticoagulants, thrombolytics, antiplatelet agents, selective serotonin reuptake inhibitors and alcoholic beverages, the risk of bleeding and ulceration of the gastric mucosa increases. Taking Aspirin with other drugs of the NSAID group increases the risk of side effects and bleeding from the gastrointestinal tract.

In addition, Aspirin may reduce the therapeutic effect of the following drugs:

• ACE inhibitors (Berlipril, Captopril, Lisinopril, Perindopril, etc.);
• Drugs that have the ability to remove uric acid from the body (Probenecid, Benzbromarone, etc.).

Aspirin for the prevention of cardiovascular and oncological diseases - video

Aspirin for children

In the developed countries of Europe and the USA, Aspirin has been banned for children under 15 years of age since the 80s of the last century, and in Russia there is no such ban. Therefore, the undesirability of the use of Aspirin in children under 15 years of age is reduced solely to recommendations.

In order to reduce body temperature, relieve pain and reduce the severity of the inflammatory process for children under 15 years of age, it is recommended to use preparations containing ibuprofen or paracetamol, since they are safer.

Application during pregnancy

During the second trimester of pregnancy, Aspirin should only be used when absolutely necessary, when it is not possible to replace it with another drug, and the benefits to the mother clearly outweigh the risks to the fetus. The maximum allowable dosage of Aspirin in the second trimester of pregnancy is 150 mg per day.

Aspirin passes into milk in a small amount, which does not cause any adverse reactions in the child. Therefore, when taking Aspirin in small doses for a short period of time, it is not necessary to stop breastfeeding and transfer the baby to formula. However, if Aspirin is taken in high doses or for a long period of time, then breastfeeding should be stopped.

Aspirin for the face from acne (mask with Aspirin)

• Cleanses the skin and removes blackheads;
• Reduces the production of fat by the skin glands;
• Narrows pores;
• Reduces inflammation on the skin;
• Prevents the formation of acne and pimples;
• Eliminates swelling;
• Eliminates acne marks;
• Exfoliates dead cells of the epidermis;
• Maintains skin elasticity.

Consider the various options for masks with Aspirin for different skin types:
1. For oily and very oily skin. The mask cleanses pores, soothes the skin and reduces inflammation. Grind 4 tablets of Aspirin into powder and mix it with a tablespoon of water, add a teaspoon of honey and vegetable oil (olive, sunflower, etc.). The resulting mixture is applied to the face and rubbed with massaging movements for 10 minutes, then rinse with warm water.
2. For normal and dry skin. The mask reduces inflammation and soothes the skin. Grind 3 Aspirin tablets and mix with a tablespoon of yogurt. Apply the mixture to your face, leave for 20 minutes and rinse with warm water.
3. For problematic skin with a lot of inflammation. The mask effectively reduces inflammation and prevents the appearance of new acne. To prepare the mask, several Aspirin tablets are crushed and poured with water until a thick slurry is formed, which is applied pointwise to acne or acne and left for 20 minutes, after which it is washed off.

Side effects

• Nausea;
• Vomit;
• Gastrointestinal bleeding (black stools, vomiting with blood, occult blood in the stool);
• Anemia due to bleeding;
• Erosive and ulcerative lesions of the digestive tract;
• Increased activity of liver enzymes (AsAT, AlAT, etc.).

• Dizziness;
• Noise in ears;
• Hearing impairment;
• Headache.

• Increased bleeding;
• Bleeding of various localization (nasal, gingival, uterine, etc.);
• Hemorrhagic purpura;
• Formation of hematomas.

• Skin rash and itching;
• Bronchospasm;
• swelling of the nasal mucosa;

The benefits and harms of aspirin - video

Contraindications for use

• Ulcer in the stomach, intestines, or esophagus;
• Hemorrhagic diathesis;
• Bronchial asthma provoked by taking other drugs of the NSAID group (Paracetamol, Indomethacin, Ibuprofen, Nimesulide, etc.);
• Thrombocytopenia (decreased level of platelets in the blood);
• Taking methotrexate at a dosage of more than 15 mg per week;
• severe renal or hepatic insufficiency;
• Heart failure in the stage of decompensation;
• I and III trimesters of pregnancy;
• The period of breastfeeding;
• Age under 15;
• Hypersensitivity to the components of Aspirin.

Aspirin's analogs

So, analogues (in the sense of synonyms) Aspirin in the form of effervescent tablets and tablets for oral administration are the following medicines:

• Aspivatrin effervescent tablets;
• Aspinat tablets and effervescent tablets;
• Aspitrin tablets;
• Asprovit effervescent tablets;
• Acetylsalicylic acid tablets;
• Acsbirin effervescent tablets;
• Nextrim Fast tablets;
• Taspir tablets are effervescent;
• Upsarin Upsa effervescent tablets;
• Fluspirin effervescent tablets.

• Aspivit effervescent tablets;
• Aspinat C effervescent tablets;
• Asprovit C effervescent tablets;
• Upsarin Upsa with vitamin C effervescent tablets.

• ASK-cardio;
• Aspicor;
• Aspinat Cardio;
• Acecardol;
• Acetylsalicylic acid Cardio;
• Cardiask;
• Cardiopyrin;
• Thrombo Ass;
• Trombogard;
• Trombopol.

Aspirin - reviews

Almost all reviews on the use of Aspirin as part of face masks are positive (more than 95%), due to the excellent cosmetic effects of the drug. Women who have used Aspirin in this way note that the masks dry out the skin, eliminate inflammation, completely remove small acne, reduce large acne, remove blackheads and narrow pores. After a course of several masks, the skin becomes much better, cleaner and more beautiful, which, of course, is liked by women who leave positive feedback on the use of Aspirin.

More than 95% of the reviews about Aspirin Cardio are also positive, which is due to a significant improvement in well-being while taking the drug, as well as normalization of the heart, which is felt not only subjectively, but is also confirmed by test and examination data. In the reviews, many people note that Aspirin Cardio is safe for the stomach and well tolerated, which is also an advantage of the drug.

Paracetamol or Aspirin?

If we are talking about an adult, then to reduce the temperature, it is recommended to first apply Paracetamol, and if it turns out to be ineffective, then take Aspirin. Aspirin is not recommended as a first-line treatment for fever as paracetamol is safer and in many cases equally effective.

For blood thinning and as part of the complex therapy of cardiovascular diseases and thrombosis, only Aspirin should be used. It is advisable to choose a specialized drug Aspirin Cardio, but if it is impossible to purchase it, you can take regular Aspirin in half or a quarter of a tablet.

Which antipyretic is better for a child: aspirin or paracetamol - video

Joint reception of Aspirin and Analgin for colds and flu

So, Analgin can cause anaphylactic shock or the almost complete disappearance of blood leukocytes, that is, conditions that quite often end in death. No less severe, but not so deadly complications of taking Analgin are persistent hypothermia (low body temperature) and collapse. Due to the rather high incidence of such side effects, Analgin has been banned for use as an antipyretic since the 60s in Europe and since the 70s in the USA. Routine use of Analgin at temperature has not been recommended by WHO since 1991.

Aspirin is able to enhance the negative effects of Analgin, which makes such a combination of drugs very dangerous. Therefore, at elevated body temperature, you should not take Aspirin and Analgin at the same time.

Cardiomagnyl and Aspirin Cardio - what's the difference?

Aspirin and Aspirin Cardio - price

Aspirin is a drug that has earned the recognition of millions of people today. This pharmaceutical agent has numerous healing properties. Influencing the human body, it has not only analgesic, but also anti-inflammatory, as well as antipyretic effect.

What are the indications for the use of aspirin?
This drug is used, as a rule, in the fight against various types of pain. It can be taken both for headaches and in case of pain in the throat, muscles, back, joints. Very often it is used by female representatives to combat pain during menstruation. Another indication for the use of this medication is considered to be elevated body temperature, which occurs against the background of colds or viral ailments. We immediately draw the attention of all readers to the fact that this remedy can be taken only if necessary, since it tends to be addictive.
hay fever, allergies, bronchial asthma, nasal polyposis. This is explained by the fact that in the presence of these ailments, the effect of this medication can be significantly enhanced. As a result, it is quite possible to develop bronchospasm or bronchial asthma. In some cases, the development of allergic reactions was also noted.

If the child has a viral infection, then he should not be given aspirin, since this medication in this particular case can cause development Reine's syndrome.

How is this syndrome diagnosed?
When present, the child has both vomiting and liver enlargement, as well as acute encephalopathy. With special attention, this medication is prescribed to patients after operations. The fact is that it tends to have an overwhelming effect directly on platelet aggregation. As a result, bleeding is quite possible, which will be very difficult to stop.

If the patient has a very low excretion of uric acid, then he should also stop using aspirin. The fact is that this medication tends to further reduce this process. Do not forget that this drug, or rather its frequent or prolonged use, can lead to addiction, so it should be used infrequently.

Aspirin (also called acetylsalicylic acid) is by far the most famous painkiller, antipyretic and anti-inflammatory drug. Acetylsalicylic acid and other chemical derivatives of salicylic acid are usually called by the common name - salicylates, which are one of the oldest medicines. Even in the distant past, in the treatment of infectious diseases, reducing pain, lowering body temperature, various infusions of willow bark were used. In 1838, scientists proved that its active ingredient is salicylic acid. In 1860, it was obtained synthetically for the first time.

For a long time, scientists have been searching for substances whose effectiveness is comparable to that of salicylic acid, but with less toxicity. A great discovery in the field of medicine and pharmacology was the preparation of acetylsalicylic acid by the French scientist S. Gerhardt. At the end of the 19th century, the German scientist F. Hoffmann developed a technology for the production of aspirin. The well-known name of acetylsalicylic acid - aspirin, consists of two parts: a- (acetyl) and -spir (Spirea - the Latin name of the plant from which salicylic acid was derived).
This drug immediately gained wide popularity. It and substances similar in composition are used in the manufacture of more than 400 drugs used for headaches and as an antipyretic. In the states, according to statistics, up to 20 tons of aspirin are consumed every year.

Aspirin is a combination drug, the effectiveness of which is achieved by a combination of the components that make up the drug. It has anti-inflammatory, antipyretic and analgesic effect, blocks platelet aggregation. Ascorbic acid stimulates redox chemical processes, carbohydrate metabolism, improves blood clotting, regenerating ability, increases the body's resistance to infectious diseases, reduces the need for certain vitamins (A, B). Satisfies the need for vitamin C in the body during fevers.
The drug is shown:
- with febrile syndrome,
- in infectious diseases,
- with inflammatory phenomena;
- with pain sensations of various origins (headache and toothache, migraine, neuralgia, etc.)
For internal use, the drug is prescribed in the following dosages:
- A moderate dose for a single dose for adults - 1-2 tablets 2-3 times a day, the maximum daily dose is 8-10 tablets; the interval for internal use should be at least 4 hours.
- For children from 10 to 14 years - no more than 1 tablet up to 3 times a day
- Children from 4 to 10 years old - 5-10 mg per kilogram of weight 3-4 times a day (with a child weighing up to 25 kg - a quarter of a tablet, with a weight of more than 25 kg - half a tablet).
Aspirin is an effective, inexpensive and affordable drug (available without a doctor's prescription), which is of great importance in the treatment of various diseases. The use of the drug should take place with strict observance of all precautions.