Vitamin B6 in ampoules and tablets: indications, instructions for use, daily allowance, signs of deficiency and excess, contraindications, side effects. Vitamin B6: what does the body need for men, women, children, during pregnancy, what products contain

Greetings, my inquisitive readers. Today we have a special guest with you - this is the “vitamin of life”. Yes, yes, you heard right. Without this element, the origin of life, its development and flow is unthinkable. What is this miracle cure? It is pyridoxine or vitamin B6.

I learned about the magical properties of this element when my son was 1 month old. And we planned to go to see a neurologist.

The fact is that during childbirth there was hypoxia. The first month for my husband and I was a real hell. Antoshka often shouted, slept very badly. I fell asleep and woke up 20 minutes later. They walked like zombies. I just wanted to sleep.

We were advised a good neurologist, and we went to see him. He examined the baby with such care. He asked about his son - about sleep, how he eats and so on. It turned out that there is a tremor and the neck mows to the left.

And then he prescribed glycine (a common amino acid) + magnesium B6 for half a tablet. Found that it is still sold in liquid form in ampoules. So we decided to give them to Antokha. After 4 days began to observe changes in behavior. Sonny after eating began to sleep for an hour, became more calm. A week later, he began to sleep through the night without waking up to eat. He wakes up on his own, examines toys, can play alone. And how he floundered in the water - he filled the whole bath.

And what impressed me was the effect of this miracle remedy. After the cancellation, the action continued anyway. I myself write and knock on wood so as not to jinx it. And then I brag to you 🙂

fell asleep while I was collecting it for a walk 🙂

Seeing such a magical effect of the vitamin on my son, I decided to find out more about B6. It turns out that this element is simply priceless - absolutely everyone needs it.

Why does the body need vitamin B6?

Pyridoxine belongs to the B vitamin family. These compounds play an important role in a number of physical and psychological functions. They are known to help maintain a healthy metabolism and the functioning of the nervous system. And such elements are also important for the health of the skin and eyes, the normal functioning of the liver.

Pyridoxine has several derivatives, including pyridoxal phosphate, pyridoxal-5-phosphate, and pyridoxamine. These important substances are involved in various biological functions of the body.

Vitamin b6 is involved in the following processes:

• supports the nervous system
• helps produce hemoglobin, which carries oxygen in red blood cells (erythrocytes) throughout the body
• balances blood sugar levels;
• helps to get energy from the food we eat;
• improves mood;
• creates antibodies that the immune system uses to protect us;
• important for hair - strengthens them and accelerates growth.

Deficiency symptoms

B6 deficiency is extremely rare in Western countries. Most people get enough calories and vitamins from food every day. Some experts even believe that some consume too high levels of pyridoxine altogether. Therefore, its excess is an even more common problem among the population than its deficiency.

With such an amount of an element, the body can easily replenish from its diet. But if you are over 50, then the dosage of b6 should be increased to 2.2 mg per day. Otherwise, the body will begin to experience a shortage.

As I said, friends, the deficiency of this vitamin is not very common. However, this problem still exists. The following symptoms help to judge the lack of element B6:

• mood changes (irritability, anxiety and depression);
• lethargy;
• muscle pain;
• chronic fatigue;
• exacerbation of PMS symptoms;
• worsening symptoms of anemia;
• insomnia;
• convulsions;
• dermatitis and yellow-lemon shade of the skin;
• deterioration of the cardiovascular system.

Most often, vitamin B6 deficiency is associated with neuropsychiatric disorders. Recent studies have shown that deficiency of this element is usually common among older people. They are at greater risk of developing Alzheimer's and other forms of dementia as B6 levels decrease.

Where is contained

This element is found in many foods that we eat. These are nuts and seeds, some types of meat and poultry, avocados, legumes.

Banana is the leader in pyridoxine content among fruits and vegetables. But there is one caveat - this is true only for those countries where it is grown. In our area, the championship is occupied by potatoes. However, in order to save b6 in it to the maximum extent, it must be properly prepared.

High levels of the vitamin are found in the following foods (at a daily intake of 2 mg for adults):

However, remember that heat treatment of food products reduces the content of this miracle element in them. For example, bread baked from white flour contains only 20% of vitamins. This is in comparison with the amount that was in wheat grains. And when boiling potatoes (if you drain the water in which vegetables were cooked), 93% of pyridoxine is lost.

Conservation also does not allow saving b6 in full. During this processing, the product loses from 57% to 77% of the vitamin. Yes, and freezing has a detrimental effect on him.

Instructions for use

For children:

For adults:

Vitamin B6 is water soluble, which means it will be excreted from the body in the urine. For this reason, as a rule, there is no particular concern in connection with an overdose. But you should not abuse this element either, because it can cause an undesirable reaction of the body.

I emphasize once again that pyridoxine is water-soluble. This means that the body is not able to store this element for future needs. Therefore, you should regularly eat foods rich in B6.

Indications for the use of an additional vitamin complex:

• anemia;
• seasickness;
• toxicosis in pregnant women;
• hepatitis;
• leukopenia;
• autism;
• dermatitis, psoriasis and other skin diseases;
• diseases of the nervous system, etc.

If you are going to buy pyridoxine supplements from a pharmacy, be sure to get a high quality product. Pyridoxine hydrochloride is sold in tablets and ampoules.

Just don't self-medicate. Everything can end up with the fact that later you will “solve the puzzle” - what is this happening to the body. And then you will definitely have to go to the doctor so that he can heal you. Agree, the price of such an experiment is too high.

Benefits of Vitamin B6

1. Supports vascular health. Pyridoxine is needed to regulate blood levels of a substance called homocysteine. It is a type of amino acid obtained from protein foods. Its high rates are associated with the development of diseases of the heart and blood vessels. Without enough vitamin B6, homocysteine ​​builds up in the body and damages blood vessels. As a result, it can provoke a heart attack or stroke. Recent studies have shown that this vitamin works best with folic acid. When patients take this "duet", the total concentration of homocysteine ​​is significantly reduced ( 2 ).
   
   
2. Supports brain function. Vitamin helps its proper development and functioning. Studies have shown that b6 deficiency can affect memory function and contribute to the development of cognitive impairment (Alzheimer's disease and age-related dementia) ( 3 ). Also, this element plays an important role in the creation of serotonin and norepinephrine. Known as “happiness hormones,” these two hormones help control mood, energy, and focus. Researchers believe that certain behavioral disorders in children are caused by low levels of serotonin. Thus, taking vitamin B6 may have a beneficial effect on children ( 4 ).
3. Improves mood. Some prescription antidepressants contain vitamin B6. It has a significant effect on the production of serotonin and the neurotransmitters GABA in the brain. These are very important hormones that control mood. They are also needed to prevent depression, pain, fatigue and anxiety ( 5 ).
4. Helps treat anemia. This element is necessary for the creation of hemoglobin in the blood. It also transports red blood cells throughout the body. This helps bring oxygen to the cells and mobilize iron. Anemia is accompanied by such symptoms: fatigue, dizziness, pain. Research shows that consuming pyridoxine may help reduce the symptoms of anemia. And in some cases, this element helps prevent this disease.
5. Protects eye health. In many cases, poor nutrition and nutritional deficiencies are the underlying causes of many eye diseases. Research has shown that taking vitamin B6 + folic acid can help prevent disease. It even helps prevent complete loss of vision.
6. Reduces symptoms of rheumatoid arthritis. Low levels of vitamin B6 are associated with increased symptoms of rheumatoid arthritis. Several studies have found that people with this condition need more B6 intake. This is because they experience constant muscle and joint pain due to chronic inflammation.
   
   
7. Helps in the treatment of hypertension. Some research suggests that taking this vitamin may help lower blood pressure in people with hypertension. This element increases blood flow and reduces its accumulation in the arteries.
8. Helps relieve symptoms of PMS. Consuming plenty of pyridoxine may help prevent painful period symptoms ( 6 ). Studies have shown that this element helps in the fight against chest pain, nausea, cramps, and fatigue. And even with acne, which is a harbinger of the menstrual cycle. For women who experience frequent PMS symptoms, it is recommended to take B vitamins regularly. It is especially important to do this 10 days before menstruation.
9. Helps reduce nausea during pregnancy. Studies have shown that taking this element is effective in reducing the severity of nausea and morning sickness. Patients were monitored for 6 weeks (24 hours a day). They noted how they felt before treatment and with vitamin B6. After this time, there was a significant reduction in nausea compared with the placebo group ( 7 ).
10. Helps in the treatment of asthma. Some studies have shown that this vitamin reduces the subsequent occurrence of asthma attacks and reduces their frequency.
11. Helps regulate sleep cycles. This wonder drug helps the body produce melatonin, which is an important hormone that helps us fall asleep. Melatonin is responsible for giving us the ability to regulate our internal clock. So we know when it's time to wake up and when it's time to sleep.
12. Prevents the formation of kidney stones. Some experience shows that taking pyridoxine along with other minerals (including magnesium) is very beneficial. It helps prevent or even cure kidney stones.

Interaction of vitamin B6 with other drugs

This item may interact with medications. Therefore, if you are already taking any medications, be sure to consult your doctor.

The list of medications that interact with vitamin B6 is huge. This list can include:

• any drugs used in chemotherapy;
• cycloserine or isoniazid - used in the treatment of tuberculosis;
• hydralazine (Apresoline) - to treat high blood pressure;
• penicillamine - prescribed in the fight against rheumatoid arthritis;
• theophylline - used to treat asthma;
• antibiotics, including tetracyclines;
• antidepressants including elavil, desipramine, imipramine and norparmin;
• some antidepressants called monoamine oxidase inhibitors (they lower blood levels of B6).

I am sure that today you have replenished your knowledge of the vital elements. And they made real discoveries for themselves in relation to pyridoxine. Don't lose your qualifications. And drop the link to the article to your friends - this info will come in handy for them. And I say goodbye to you - until we meet again.

Vitamin B6 (Pyridoxine) - physiological role, signs of deficiency, content in food. Instructions for use of vitamin B6

Thanks

Vitamin B 6 is a group name for three mutually transforming forms of the same bioorganic compound. Different forms of a single compound are called spatial conformations and have different names that are used to quickly and easily distinguish them in written and spoken language. However, the common name for vitamin B6 is pyridoxine.

Name of vitamin B 6

Figure 1 - Examples of hexane isomers.

Vitamin B 6 consists of three vitamers-isomers, each of which has the same vitamin activity. Vitamers are called differently - pyridoxol (pyridoxine), pyridoxal and pyridoxamine. All of these names can be used to refer to some form of vitamin B 6 . However, to avoid confusion, vitamin B 6, on the recommendation of the International Commission on the Nomenclature of Biological Chemistry, is called pyridoxine, meaning by this name all three structural forms that have the same activity - pyridoxine (pyridoxol), pyridoxal and pyridoxamine.

In addition, vitamin B 6 is sometimes called the old names - adermin or Y factor, which were given to matter several decades ago during their discovery and study of properties. Today, these names are rarely used in relation to vitamin B 6, but they can still be found in some scientific and popular science publications.

In the human body, all three vitamers of vitamin B 6 - pyridoxol, pyridoxal and pyridoxamine are converted into two active forms - pyridoxal phosphate and pyridoxamine phosphate. It is in the form of pyridoxal phosphate and pyridoxamine phosphate that vitamin B 6 has physiological and biological effects in the human body. These names are also sometimes used in the literature to indicate that we are talking about the active form of vitamin B 6 .

The physiological role of vitamin B 6

Vitamin B 6 has three listed physiological effects at the level of each cell. Then the effect is summed up and there is a general action at the level of the whole organism. Let us consider in detail what is the essence of each physiological effect of vitamin B 6, and what role they play in the maintenance and regulation of vital processes.

So, at the level of protein metabolism, pyridoxine is necessary for the mutual conversion and metabolism of amino acids that occur during the reactions of transamination, transamination, deamination and decarboxylation. It is the course of these reactions that triggers and maintains vitamin B 6 at the required level. The mutual transformation of amino acids occurs in the body constantly, when it is necessary from one compound, which at the moment is quite a lot, to get another - available in insufficient quantities. Thanks to this mechanism, one amino acid can turn into another - the one that is needed right now for various processes of protein synthesis. The process of converting amino acids into each other allows you to maintain a dynamic balance and prevent the occurrence of deficiency due to the conversion of another substance that is available in excess. In addition, vitamin B 6 improves the absorption of amino acids from the intestines into the bloodstream and their subsequent transportation to various organs and tissues.

In addition, vitamin B 6 supports, activates and accelerates the conversion of dopamine to norepinephrine and glutamic and aspartic acid to succinic acid, which significantly increase the rate of energy processes in cells. This means that under the influence of vitamin B 6, metabolism is accelerated, metabolism is faster, and, consequently, all cells are renewed in a shorter period of time, maintaining youth and activity of the whole organism.

In the course of deamination reactions, the formation of acetyl coenzyme A, which is a key substance for the course of Krebs cycle. And the Krebs cycle is necessary for the synthesis of a universal energy molecule ATP (adenosine triphosphoric acid) from carbohydrates. The importance of the ATP molecule cannot be overestimated - after all, each cell uses energy in this form, and not in the form of proteins, fats and carbohydrates that come with food. Thus, in order to obtain a universal energy substrate, the cell needs to process carbohydrates, proteins and fats into ATP molecules. And vitamin B 6 ensures the flow of a cascade of reactions (the Krebs cycle), during which carbohydrates are processed into ATP.

During decarboxylation reactions, gamma-aminobutyric acid (GABA) is formed from glutamic acid and serotonin from tryptophan. And gamma-aminobutyric acid and serotonin, in turn, are the main inhibitory mediators in the central nervous system. That is, under the influence of GABA and serotonin, inhibition and damping of excitation in the central nervous system occurs. And since the decarboxylation reaction, during which the formation of GABA and serotonin occurs, is regulated and triggered by vitamin B 6, in this way pyridoxine regulates the excitability of the central nervous system, preventing it from becoming excessively increased. That is why, with a deficiency of vitamin B 6, signs of excessive excitation of the central nervous system appear, such as a tendency to convulsions, exaltation, etc.

Finally, vitamin B 6 increases the amount of synthesized protein siderophilin, which carries out the transfer of iron from the intestine to tissues, including the bone marrow. Thus, pyridoxine provides the bone marrow with enough iron for hematopoiesis. And therefore, with a deficiency of vitamin B 6, anemia can develop, because it is simply impossible to deliver iron to the bone marrow, where hemoglobin is formed from it, due to a lack of siderophilin protein.

Vitamin B 6 for children - features of biological function

In children, the ability of vitamin B 6 to ensure the conversion of amino acids into each other is of great importance, since they are necessary for protein synthesis and building muscles, bones, connective tissue, blood vessels, nerves, etc. Summarizing, we can say that active protein synthesis is necessary for a child for normal growth and harmonious physical development. And at any particular moment in time, there may be a deficiency of one or another amino acid, without which it is impossible to build a protein. And then, in the literal sense of the word, vitamin B 6 comes to the rescue, which starts the process of converting one amino acid in excess into another - the one that is now lacking. That is, pyridoxine in children ensures normal physical development and full growth.

The function of maintaining protein synthesis is important not only for growth, but also for normal immunity. After all, antibodies or immunoglobulins are protein structures that are constantly synthesized in the body to destroy various pathogenic bacteria, viruses, fungi, etc. And against the background of a deficiency of vitamin B 6, the synthesis of immunoglobulins can occur with insufficient intensity, which will manifest itself as a decrease in immunity in a child.

Also, vitamin B 6 is involved in the synthesis of insulin, a protein that is very important for the utilization of glucose, with an insufficient amount of which a person develops a severe, chronic metabolic disease - diabetes mellitus.

In addition, vitamin B 6 is necessary for the synthesis of a sufficient amount of hemoglobin, since it stimulates the formation of a protein that delivers iron to the bone marrow, where hemoglobin is assembled. For children, this is especially important because they grow rapidly, and their blood volume is constantly increasing. If the volume of blood increases without a proportional increase in the amount of hemoglobin, then the child will develop anemia.

Also, for children, the ability of vitamin B 6 to suppress excitation and activate inhibition in the central nervous system is very important. Given the prevalence of excitation over inhibition in the brain in children, it becomes clear that vitamin B 6 is very important for maintaining balance and preventing convulsive activity, irritability and excitability.

Pyridoxine is also very important for skin health, since the vitamin prevents dermatitis of any origin, including allergic, seborrheic, fungal, psoriatic and diathesis. Given that children often develop inflammatory and itchy rashes on the skin, the role of vitamin B 6 as a substance that prevents these phenomena is very important.

Absorption and excretion of vitamin B 6

Vitamin B 6 deficiency - symptoms

Separately, it is worth mentioning the use of drugs that prevent the absorption of pyridoxine into the blood from the intestine as the reasons for the development of vitamin B6 deficiency. These drugs include anti-tuberculosis (isoniazid, ftivazid, tubazid, cycloserine) and some other antibiotics (penicillamine, chloramphenicol), as well as Ethionamide, Levodopa, estrogens and immunosuppressants.

Symptoms of Vitamin B6 Deficiency in Adults

• Deterioration of appetite up to its complete loss;
• Irritability;
• lethargy;
• Depression;
• Strong anxiety;
• Convulsions and high convulsive activity;
• Seborrheic dermatitis;
• Hair loss;
• Formation of kidney stones;
• The appearance of abnormal waves on the electroencephalogram (EEG);
• Neuritis and polyneuritis of peripheral nerves;
• Inflammation of the tongue (glossitis);
• Dryness and roughness of the skin on the face, especially around the eyes and lips;
• Vertical and deep cracks on the lips;
• Cracks in the corners of the mouth;
• Numbness of the limbs;
• muscle weakness;
• Reduced immunity by reducing the number of T-lymphocytes.

Symptoms of vitamin B6 deficiency in children

• Delayed growth and physical development;
• convulsive attacks;
• High convulsive readiness and convulsions;
• Increased excitability;
• Disorders of the digestive tract (flatulence, diarrhea, etc.);
• Dermatitis with a pronounced inflammatory reaction.

Vitamin B 6 in foods

• Walnuts;
• Hazelnut;
• Potato;
• White cabbage;
• Cherries;
• Horseradish;
• Yeast;
• Sweet bell pepper;

The products listed above contain the maximum amount of vitamin B 6. Pyridoxine is found in somewhat smaller but also sufficient amounts in legumes (beans, beans, peas, nahut, lentils), fish, meat, dairy products, liver of animals and birds, as well as cereals and eggs.

Foods rich in vitamin B 6 - video

Daily intake of vitamin B 6 people of different ages

• Children from birth to six months - 0.1 mg per day;
• Children 7 - 12 months - 0.3 mg;
• Children 1 - 3 years old - 0.5 mg;
• Children 4 - 8 years old - 0.6 mg;
• Children 9 - 13 years old - 1.0 mg.

The above are indicative average vitamin intake per day, which should be tried to be observed daily. However, if during a week a person receives less vitamin B 6 from food for several days, and on other days, on the contrary, consumes it in excess, then the dynamic balance will not be disturbed due to overlap, and in general the body will not experience a lack of pyridoxine.

These norms are calculated for healthy people leading a moderately active lifestyle. However, with nerve tension, physical exertion, staying in the cold, working with chemicals and radionuclides, the need for vitamin B 6 increases.

It is recommended to calculate the individual intake of pyridoxine based on the amount of protein in the diet, based on the ratio: 0.032 mg of vitamin B 6 for every 1 g of protein. With dietary nutrition, the minimum sufficient intake of pyridoxine is 1 mg, and the maximum allowable is 6 mg.

In the treatment of various diseases, the dosage of vitamin B 6 by some clinicians is brought up to 600 mg per day. Usually this dose is tolerated without any negative consequences. However, scientists recommend not to exceed the daily dosage of pyridoxine more than 50 mg.

Forms of vitamin B 6 for medical use

Accordingly, vitamin B 6 tablets are taken orally, and the solution is administered intramuscularly, intravenously or subcutaneously. With acne, a solution of vitamin B 6 is applied externally in the form of lotions and applications to the affected areas.

In addition to the two dosage forms, the vitamin B 6 preparation for medical use may contain various vitamers as the active substance, such as pyridoxine hydrochloride or pyridoxal phosphate. The preparation of vitamin B 6 containing pyridoxal phosphate as an active substance has a faster therapeutic effect compared to pyridoxine hydrochloride. Otherwise, the properties of preparations with pyridoxine hydrochloride and pyridoxal phosphate are the same.

Vitamin B 6 - indications for use

A separate article of the use of vitamin B 6 is the prevention of the development of hypovitaminosis in the treatment of tuberculosis with antibiotics. The fact is that anti-tuberculosis antibiotics consume vitamin B 6 in large quantities, therefore, even against the background of its normal intake with food, a deficient state (hypovitaminosis or beriberi) may form after a while. Therefore, when using anti-tuberculosis antibiotics, it is necessary to additionally take vitamin B 6. Currently, many new anti-tuberculosis drugs are produced in a combined form that includes an antibiotic and vitamin B 6 . This combined form allows only one drug to be taken and eliminates the need for additional and separate use of pyridoxine.

Today, the general indications for the use of vitamin B 6 are the following conditions:

• Early toxemia of pregnancy with nausea and frequent vomiting;
• Newborns on artificial feeding, produced not by balanced specialized infant formulas, but by donor milk or milk of farm animals;
• Formula-fed newborns suffering from dryness, swelling and peeling of the skin;
• Newborns with low body weight (hypotrophy);
• Newborns with pyridoxine-dependent convulsive syndrome (hereditary disease);
• Anemia, combined with a high concentration of iron in the blood (hypochromic microcytic anemia);
• People with low resistance to various infectious diseases;
• People with increased excitability;
• People of any age, including children, suffering from febrile seizures (convulsions that develop in response to high body temperature);
• heart failure;
• As part of the complex therapy of hepatitis and cholecystitis;
• As part of the complex therapy of parkinsonism;
• As part of the complex therapy of sciatica;
• Peripheral neuritis;
• Neuralgia;
• Prevention of seizures during the course of Ftivazid;
• Prevention of hypovitaminosis during the course of treatment with anti-tuberculosis antibiotics;
• Malnutrition;
• Long-term infectious diseases;
• To replenish the loss of vitamin B 6 with diarrhea;
• Enteritis (for the prevention of hypovitaminosis against the background of impaired absorption of pyridoxine through the inflamed intestinal wall);
• Prolonged stress;
• Malabsorption syndrome;
• Conditions after removal of the stomach or part of the intestine;
• Little's disease;
• Alcoholism;
• Dermatitis (atopic, seborrheic, acne, pimples, etc.);
• Herpetic infections (herpes simplex, chickenpox, etc.);

Vitamin B 6 in ampoules - characteristics and names of drugs

A solution of vitamin B 6 in ampoules is produced and sold under the following commercial names:

• Pyridoxine (vitamin B 6);
• Pyridoxine Bufus (Vitamin B 6);
• Pyridoxine-Vial (Vitamin B 6).

Vitamin B 6 tablets - characteristics and names of drugs

• Pyridoxine hydrochloride;
• Pyridoxine (vitamin B 6).

These drugs are monocomponent, that is, they contain only one active substance - vitamin B 6. In addition to these monocomponent preparations, there is a wide range of complex products containing several vitamins, including B 6 . The list of complex products containing vitamin B 6 in the composition will be reflected in a separate section.

Complex preparations with vitamin B 6

Therapeutic preparations of vitamins contain several components - from two to five. Moreover, these components are selected for compatibility with each other and ease of use. For example, complexes of vitamins B 6 + B 12, which are very convenient to use, since they allow you to enter both compounds at once in one injection. Such complexes contain vitamins in rather large, therapeutic dosages and are used as part of the complex therapy of various diseases. That is why they are called therapeutic drugs. Below is a list of complex therapeutic drugs containing vitamin B 6:

• Angiovit (B 6, B 12 + folic acid);
• Binavit (B 6, B 1 and B 12 + lidocaine);
• Biotredin (B 6 + amino acid threonine);
• Vitagamma (B 6, B 1 and B 12 + lidocaine);
• Vitaxon (B 6 , B 1 and B 12 + lidocaine);
• Combilipen (B 6 , B 1 and B 12 + lidocaine);
• Compligam B (B 6 , B 1 and B 12 + lidocaine);
• Lysobact (B 6 + lysozyme);
• Magvit (magnesium citrate + B 6);
• Magne B6 (magnesium + B 6);
• Magnelis B6 (magnesium lactate + B 6);
• Magnesium plus B6 (magnesium lactate + B 6);
• Medivitan (B 6 , B 12 and folic acid);
• Mexi B6 (B 6 + ethylmethylhydroxypyridine succinate);
• Milgamma (B 6, B 1 and B 12);
• Milgamma compositum (B 6 and B 1);
• Multi-Tabs B-complex (B 1, B 2, B 3, B 5, B 6, B 12 + folic acid);
• Neurogamma (B 1 and B 6);
• Neurobion (B 6 , B 1 and B 12);
• Neuromultivit (B 6 , B 1 and B 12);
• Pentovit (B 1, B3, B 6, B 12 + folic acid);
• Pitzian (B 6 and B 12);
• Polyneurin (B 6 and B 1);
• Trigamma (B 6, B 1 and B 12 + lidocaine).

Vitamin B 6 - instructions for use

The choice of method of administration of vitamin B 6 depends on what the drug is used for. So, for the treatment of moderate hypovitaminosis or its prevention, as well as to improve the condition of the skin, hair and nails, vitamin B 6 is recommended to be taken in the form of tablets. To eliminate severe hypovitaminosis or beriberi, as well as in the complex treatment of various diseases, vitamin B 6 is recommended to be used in the form of injections. Also, vitamin B 6 must be injected if a person suffers from inflammatory or ulcerative diseases of the digestive tract, in which normal absorption of the drug from the intestine is impossible.

The choice of injection route (intravenous, intramuscular or subcutaneous) is based on the capabilities of healthcare professionals and patients. The drug begins to act most quickly when administered intravenously, which must be used in acute conditions. In the treatment of chronic pathologies, if a person cannot attend a medical facility for intravenous administration of vitamin B 6, he needs to switch to intramuscular or subcutaneous injections at home.

An injection of vitamin B 6 - how to administer the drug correctly

• Therapy with anti-tuberculosis antibiotics - administer vitamin B 6 at 5-10 mg per day during the entire course of treatment;
• Sideroblastic anemia - 100 mg per day, intramuscularly twice a week;
• Parkinsonism - 100 mg per day, intramuscularly twice a week. The course of treatment consists of 20-25 injections. Repeated courses are carried out after a break of 2 - 3 months.
• Depression - 200 mg per day, intramuscularly.

An intramuscular injection is recommended to be given to the lateral surface of the upper third of the thigh, and not to the buttock, since an injection into the muscles of the leg is much safer. To make an injection, it is necessary to free the outer surface of the upper third of the thigh from clothing, wipe the skin at the injection site with an antiseptic (alcohol, chlorhexidine, etc.), then gently break off the tip of the ampoule with the solution, insert the tip of the syringe needle into it and draw the right amount of the drug. Then turn the syringe upside down with the needle up and lightly tap on the surface of the tube in the direction from the piston to the needle so that air bubbles break away from the walls and collect on the surface of the solution. Then lightly press the plunger and release a few drops of the drug from the needle. After that, with a quick and gentle movement, insert the needle deep into the muscle, placing it perpendicular to the surface of the skin of the thigh. Slowly pressing the plunger, inject all the medicine into the muscle, then carefully withdraw the needle, keeping the syringe still perpendicular to the skin surface. Wipe the injection site with an antiseptic.

Subcutaneous injection is best done on the forearms of the hands. Before the injection, wipe the skin with an antiseptic and draw the medicine into the syringe. Release a drop of solution from the syringe to remove air, and close the needle with a cap. Put the finished syringe on a clean surface so that it can be reached by hand. Then, with your left hand, fold a skin area of ​​1-1.5 cm into a fold and hold it in this way until the end of the injection. Take the syringe with your right hand, remove the cap and insert the needle under the skin fold, holding it parallel to the forearm bone. Slowly inject the entire volume of the solution and remove the syringe, continuing to hold the skin fold with your left hand. After the needle is removed, you can let go of the skin and wipe the injection site with an antiseptic.

It is not recommended to do intravenous injections on your own, because without the proper skill it is dangerous and painful. For intravenous administration of vitamin B 6, you should use the services of a professional nurse.

Instructions for the use of vitamin B 6 inside

Vitamin B 6 - use for various purposes

Vitamin B 6 for hair

Mask with vitamin B 6 for hair

Vitamin B6 (pyridoxine) has long been in the shadow of other biologically active substances, until it turned out that its deficiency causes about 100 diseases. Consider what is its value for a person, in what form it is sold in pharmacies, what is the drug in ampoules, instructions for its use, use in facial skin and hair care.

What is vitamin B6

Pyridoxine (P) is the name of a group of three substances that are equivalent in properties and action. All of them are water-soluble, therefore they do not linger in the internal environment of the body and must constantly come from outside with food. Resistant to heat and the presence of oxygen, but destroyed in the light.

They play an important role in metabolic processes:

• necessary for the synthesis of serotonin (happiness hormone) and other neurotransmitters;
• help the normal functioning of the liver;
• ensure the absorption of lipids and proteins;
• regulate myocardial contractility;
• participate in amino acid metabolism;
• affect immunity and hematopoiesis;
• remove homocysteine, a high level of which provokes strokes and heart attacks;
• have diuretic properties;
• reduce blood pressure.

In addition, P ensures the correct synthesis of DNA, which prevents the aging of the body.

Pyridoxine is not an independent medicine, but complex medical care is impossible without it for a number of conditions:

• Treatment of hypovitaminosis b6 that occurs with malnutrition. Pyridoxine deficiency is accompanied by dermatitis, depression, insomnia, polyneuritis of the extremities, conjunctivitis. Its deficiency occurs with ongoing infections, diarrhea, prolonged stress, hemodialysis, after surgery to remove fragments of the digestive canal.
• As part of the treatment of parkinsonism, anemia, sciatica, neuritis, convulsions in newborns, alcoholism, hepatitis.
• It is indicated for diagnoses of "dermatitis, herpes, diathesis, scaly lichen".

Vitamin b6:

• quickly restore damaged tissue;
• normalizes the functioning of the nervous system;
• lower cholesterol levels and positively affect the functionality of the myocardium, which is the prevention of pathologies of the heart and blood vessels;
• provide better absorption of magnesium;
• help with syndromes leading to skin diseases;
• normalizes the mechanisms of hematopoiesis.

Pyridoxine is necessary in the treatment of childhood autism, epilepsy, and brings a person out of a state of binge. At the same time, it is only an auxiliary compound that improves the course of therapeutic measures.

As the main substance, it serves as an antidote for poisoning with hydrazine and isoniazid. The latter is the most commonly prescribed medication for infection with a tuberculosis bacillus, but its use is accompanied by multiple side effects. Vitamin B6 reduces the intensity of toxicity. The doctor prescribes tablets P in the amount of 5-10 mg / day during the entire treatment course.

Pyridoxine is contraindicated in patients with individual intolerance. Caution is required when taking it with ischemia of the heart, gastric and duodenal ulcers, and liver pathologies.

Instructions for use

Pyridoxine tablets (2, 5 and 10 mg) can be bought without a prescription. With toxicosis of pregnant women take pills (10-20 mg). If you are concerned about vomiting, a course is indicated for 10-20 days with a daily dose of 50 mg.

Vitamin B6 in ampoules is taken only on prescription, which takes into account the type of pathology. Preparations for injection with a volume of 1 or 2 ml contain 50 mg of the active ingredient in 1 ml of solution.

To prevent a lack of b6, the introduction of P into the skin or vein is practiced. The daily dose is 50-100 mg in 2 divided doses. With the diagnosis of sideroblastic anemia, 100 mg of the drug is administered intramuscularly 2 times a week. For the treatment of parkinsonism, you will need a course of 20-25 injections with daily intramuscular injection of 2 ml of a solution (5%) of pyridoxine chloride.

The use of vitamin B6 in ampoules

P injections are indicated when the patient has problems with swallowing or alimentary canal function. As a rule, these are difficult cases:

• fainting, mental disorders, nausea and vomiting;
• malabsorption, intestinal pathology, enteritis, acute form of diarrhea, postoperative period;
• toxicosis of pregnancy;
• the need for shock dosages P. They are used for leukopenia, as they help to synthesize proteins, without which the formation of white blood cells is impossible. Indicated in Meniere's disease, because they slow down the filling of the middle ear cavity with fluid.

If anemia is the result of magnesium deficiency, then the doctor prescribes a complex drug, such as Magnelis B6. Pyridoxine from their composition is designed to improve the absorption of Mg as an essential trace element. Dosages are determined by the doctor after receiving the results of laboratory tests. On average: 6-8 tablets for adults and 4-6 for children weighing 20 kg. Scheme of administration: 3 times a day after meals for a month.

Pharmacies offer to buy vitamin B6 in ampoules under different names. They are identical in action, they contain, as a rule, lidocaine, for pain relief when administered intramuscularly. The injection site is the gluteal muscle, namely its upper outer region. Doctors prefer infusions at different rates, at which the active substance is practically not lost.

Compatibility

Pyridoxine is not administered simultaneously with vitamins B1 and B12. Its effectiveness drops when combined with ascorbic and nicotinic acid. Incompatible with anti-tuberculosis compounds, penicillamine, cycloserine and cuprimine. The concentrations of phenytoin and phenobarbital are reduced when taken together with it. P enhances the effectiveness of glycosides in the treatment of heart pathologies. Hypoxia weakens if P is combined with asparkam and glutamic acid.

Overdose

Pyridoxine belongs to low-toxic compounds. High doses of it rarely lead to poisoning, but sometimes this does happen. This condition is accompanied by pronounced side effects, including:

• allergies with skin rashes;
• convulsions (with rapid introduction);
• numbness;
• fainting, dizziness;
• increased acidity of gastric juice.

If at least one of these signs appears, taking drugs with vitamin B6 is canceled. After a while, all the symptoms of an overdose disappear on their own. If the patient's condition does not improve, he is hospitalized.

Pharmacy price

Pyridoxine is one of the most affordable drugs. The price of vitamin B6 in ampoules (10 pieces of 1 ml of a 5% solution) is about 30 rubles.

Vitamin B6 in cosmetology

Pyridoxine is not always used for its intended purpose. Women experiment with it, caring for their skin. There are many options for nourishing and moisturizing formulations based on it. The most popular include mixtures that include grated banana, 1 tbsp. l. sour cream, 1 ampoule B6. Multiplicity of application: 2 times a week. For the second option, which will get rid of acne, you will need: natural honey, kefir, lemon juice and pyridoxine.

Vitamin b6 in hair ampoules

The inclusion of P in the composition of shampoos and masks heals and strengthens curls. With it, the state of the sebaceous glands is normalized, the skin retains moisture, and dandruff disappears. Tablets are not suitable for the preparation of such formulations.

It is better that the vitamin gets inside with food. Using it for external influence provides an auxiliary, but weak effect. In other words, with a deficit in the intake of pyridoxine with food, masks and shampoos with it are not able to compensate for such a deficiency.

The best option is the parallel use of the vitamin both through the gastrointestinal tract and for external exposure. For the latest version, you can prepare different concentrations of the main component. Pour the contents of 3 ampoules into a 250 ml container with herbal shampoo or conditioner, then use as usual when washing your hair.

For a disposable mask, respectively, you will need 1 ampoule with the drug. Its contents can be combined with various berries, fruits, lemon juice, honey, beaten egg, infusions of linden, chamomile, burdock, almond or sea buckthorn oil. Warm the head with a film and a towel. Exposure time is about 1 hour. There are no specific dosages. Everything is individual. If urticaria or itching appears, cancel the procedure.

Before preparing and taking pyridoxine-based cosmetics, you should visit a doctor to find out what is causing the poor condition of the hair. The reason may be an excess of biologically active substances or other disorders. Be sure to read the instructions for vitamin B6 in ampoules. When a deficiency is identified, it is better to start with a diet correction.

If there is a need for the use of IUDs, then their choice should also be entrusted to a specialist. The optimal composition of useful elements for hair is offered by preparations:

• Fitoval;
• Sheviton;
• Nutrical.

To support the skin, special formulations have been developed:

• Vitrum Beauty;
• Complivit Radiance;
• Beautician;
• Alphabet.

They are often more beneficial than vitamin B6 masks and shampoos.

The source of natural pyridoxine are some foods:

• a fish;
• meat by-products;
• potato;
• unrefined cereals;
• nuts;
• bananas;
• green vegetables.

The daily dose for adults is 1-1.3 mg of pyridoxine. A balanced diet fully meets the needs of the body. In severe shortages, injections may be an additional source.

Vitamin B6 is a drug that requires a responsible attitude. Self-medication or experimentation with its use can seriously harm. To avoid trouble, pyridoxine should be taken as directed and under the supervision of a physician.

According to scientists, which is based on their numerous studies, a modern person does not receive the necessary norm of useful substances (vitamins, minerals). We usually get these substances from food. But few modern people follow the principles of a healthy, balanced diet, preferring snacks, convenience foods and mono-diets. Hence the appearance of a deficiency of vitamins, minerals, and other essential substances.

Very often the body lacks vitamin B6. It is one of the vital elements needed for health. His daily requirement is 2.0 mg per day and no less. Vitamin B6 is involved in the synthesis of serotonin, known as the hormone of happiness. Therefore, it is often referred to as a vitamin - an antidepressant. In the presence of the required amount of B6 in the blood, a person does not lose mental balance, he often experiences joyful emotions, being in a good psycho-emotional state.

With its deficiency, a person suffers from insomnia, dermatitis develops on the skin, and bouts of irritability increasingly occur. Also, the deficiency of this substance has a negative effect on the liver.

Any modern pharmacy offers vitamin B6 ampoules or tablets. Each package contains instructions for this drug. But you can additionally take vitamin B6 only as prescribed by a doctor, after an appropriate medical examination. Remember that an excess of it is no less dangerous than a deficiency. But to treat the consequences of such an overabundance is much more difficult.

What are the indications for the use of vitamin B6?

First of all, the drug is prescribed in the presence of hypo- and vitamin deficiency of this particular substance. This often happens with various diets, poor nutrition. It is also indicated in the treatment of long-term infectious diseases.

The drug is effective in diarrhea, enteritis, malabsorption syndrome. It is prescribed for stressful conditions, as well as a condition after resection of the stomach, intestines. Recommended for hemodialysis.

Vitamin is prescribed as part of the complex therapy of hypochromic or microcytic anemia. Included in the treatment of Parkinson's disease, sciatica, Little's disease, neuritis and neuralgia.

Applied in the treatment of congenital pyridoxine-dependent convulsive syndrome, sometimes observed in newborns. It is prescribed as a means of preventing convulsive conditions in patients while taking ftivazid.

Assign in the complex therapy of preeclampsia, alcoholism. With liver pathologies that appeared against the background of the use of ethanol or anti-tuberculosis drugs. Often it is recommended to take it to patients with hepatitis, in order to enhance diuresis, enhance the action of diuretic drugs.

Vitamin B6 is often prescribed to cores to regulate pressure. It is advised to take in the treatment of depression.

Often, preparations with this vitamin are prescribed for skin diseases - lichen dermatitis, with frequent exacerbations of herpes and psoriasis. Assign with neurodermatitis, in the treatment of seborrhea, exudative diathesis.

Assign in the treatment of autism, epilepsy. The drug is indicated for patients with generalized anxiety.

What is the vitamin B6 medication dosage and use?

Tablets:

The drug in tablets is taken after meals. For prophylactic purposes, take 0.002-0.005 g per day for adults.

What is the use of vitamin B6 in injection solution?

Vitamin is administered intramuscularly:

In the treatment of sideroblastic anemia - 100 mg twice a week. At the same time, folic acid, cyanocobalamin and riboflavin are usually prescribed.

In the treatment of parkinsonism - 100 mg per day. The course of conduction is 20-25 injections. If necessary, the treatment is repeated after 2-3 months.

In the treatment of depressive conditions of involutionary age - 200 mg per day with intramuscular injection.

During the treatment of convulsive syndrome (pyridoxine-dependent):

Adults: in / in or in / m - 30-600 mg per day.
Children: 10-100 mg per day.

What are the contraindications for vitamin B6?

Do not prescribe an additional dose, or treatment using B6 in patients with hypersensitivity. For strict restrictions on the preparation of vitamin B6, the instructions for use call patients with peptic ulcer disease, as well as those suffering from cardiac ischemia.

What are the side effects of vitamin b6?

When using drugs - sources of this substance, allergic manifestations are possible, such as skin rashes, swelling, redness of the skin, itching. Hypersecretion of HCl may be observed. Sometimes the patient complains of a feeling of squeezing in the arms and legs. In lactating women, there is a decrease in lactation. With the rapid administration of the drug, convulsions may occur.

You will learn even more detailed information about the properties and use of vitamin B6 from the original paper instructions, which you will find in the package with the drug.

Do not self-prescribe medications. Do not risk your own health, always ask your doctor for a prescription. Be healthy!

• Processing of amino acids.
• Participation in the formation of red blood cells.
• Assimilation of glucose by nerve cells.
• Regulates fat metabolism.
• It has a lipotropic effect (improves liver activity).
• It has an immunostimulating effect.
• Promotes the removal of cholesterol.
• Normalizes cardiovascular activity.

Indications and contraindications

The main factor in the loss of B6 is nervous tension, stress. Constant replenishment of the vitamin is required for people whose life activity is associated with sports and physical activity.

B6 deficiency in women during pregnancy and lactation - 100% (for comparison: deficiency of ascorbic acid in a pregnant woman - 64%). Less often, there is a lack of vitamin B6 in children, it increases with age, the highest is in men and women over 50.

Indications for use

1. Avitaminosis.
2. Blood diseases - leukopenia, etc.
3. Toxicosis during pregnancy.
4. Diseases of the nervous system: sciatica, neuralgia, neuritis, etc.
5. Parkinson's disease.
6. Diabetes. (about vitamins for diabetics)
7. Nausea during motion sickness, manifestations of sea and air sickness.
8. Atherosclerosis.
9. Meniere's disease.
10. Fungal skin lesions, dermatitis.
11. Cardiovascular disorders.
12. Non-severe diseases of the liver and gastrointestinal tract.

Contraindications:

1. Severe diseases of the gastrointestinal tract (ulcers in the acute stage, etc.), biliary tract, liver.
2. Ischemic disease.

Deficiency and its symptoms

Symptoms of vitamin B6 deficiency: fatigue, drowsiness, depression, muscle weakness, circulatory disorders, hair loss.

Chronic vitamin deficiency in the body is the cause of nervous disorders, cardiovascular diseases, dermatitis, arthritis, liver and biliary tract diseases. In total, the lack of B6 is due to the development of more than 100 diseases.

How to make up the deficit?

Vitamin B6 is found in foods:

• germinated wheat;
• grain in the husk (buckwheat, rice);
• bran;
• yeast;
• dry beans, soybeans, beans;
• liver (beef liver, etc.)
• egg yolk;
• dairy products and molasses;
• seafood;
• cabbage, white and cauliflower;
• potatoes, sweet potato;
• carrot;
• spinach;
• bananas, avocados;
• citrus;
• nuts: hazelnuts, walnuts.

Of all the foods that contain vitamin B6, protein and grains are considered the richest. Medicinal herbs with a high content - plantain, catnip, alfalfa and oat stalks.

Pharmaceuticals:

1. Vitamin B6 (Pyridoxin) is sold in 1 mm ampoules (10 pcs.), Three dosages (0.05 g, 0.1 and 0.15), the average price is 20-25 rubles.
2. Vitamin B6 in tablets and powders (100 pcs.), Dosage 0.002 and 0.01, price 300 rubles.
3. Vitamin Magne B6: release form - ampoules. For breeding and oral administration, the average price is 300 rubles.

Overdose

An overdose of B6 is rare, because. it does not accumulate, it is excreted in the urine. With excessive use of the drug possible short-term nervous breakdown and numbness of the extremities(as with any vitamin intoxication). Diseases caused by an excess of B6 have not been identified.

Side effects: allergic reactions, itching, skin rashes. Increased acidity.

Combination with other substances

1. Incompatible with vitamins C, B1 - neutralize each other's action.
2. With B12 can only be taken at intervals of time.
3. Combines well with B2, K and B5.
4. It is prescribed together with cardiac glycosides in the treatment of vascular disorders, as well as with asparkam and glutamic acid to increase resistance to hypoxia. (More about)
5. It goes well with, as well as preparations of magnesium, calcium, zinc - it prevents the removal of these metals from the body.
6. Reduce the amount of B6 alcohol, oral contraceptives, anti-tuberculosis drugs, antibiotics.

Brief instructions for use and daily requirement

In tablets

The daily rate is divided in half, morning and evening. The course is from one to three months. A consultation with the attending physician is highly desirable, as well as a careful study of the instructions for use.

Daily value (approximately) in mcg:

• Children under 6 months - 0.1 per day;
• Up to a year - 0.3;
• Up to 3 years - 0.5;
• Up to 8 - 0.6;
• Up to 13 - 1;
• Boys under 18 - 1.3;
• Girls under 18 - 1.2;
• Women - 1.3;
• Pregnant women - 2.0;
• During lactation - 2.2;
• Men - 1.7;
• Athletes - 2.2;
• Elderly women - 1.5;
• Elderly men - 1.7.

In ampoules

How to inject vitamin B6? intramuscularly, in the gluteal muscle or upper thigh. Dial into the syringe, turn over, drive the air bubbles up, release the air.

Slightly pull the skin, wipe with a swab dipped in alcohol. Enter slowly, at the end of the injection site wipe with an alcohol swab.

Vitamin B6 injections are painful and should not be used without medical advice.

Vitamin Magne B6 in ampoules, application: adults and children older than a year (from 10 kilograms) recommended dose - no more than 4 ampoules per day. Divided into two or three doses. The contents of the ampoule should be mixed in ½ cup of water. Take with food.

From hair loss

The mask works great, which is made up of a beaten egg, three oils (sea buckthorn, almond, burdock) one spoon each and the contents of three ampoules: B6, B2, B12. Keep the mixture on the hair under the film for an hour, rinse with shampoo.

The second option: the same with the addition of honey, castor oil, lemon juice, vitamins A, E, D. Hold for forty minutes.

Vitamin is excreted from the body in eight hours. Needs regular replenishment. B6 contained in food is usually not enough for optimal vitamin balance.

But before prescribing treatment for yourself, you should consult a therapist, even if you definitely have no contraindications to use. The doctor will suggest the most appropriate regimen for taking B6 and tell you which drugs it should not be used with.

Look for all the details about B vitamins, their properties and daily allowance at.